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114843 results for "6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one"

114843 Results for: "6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one"

XPert™ Bulk Powder Enclosures, Labconco®

XPert™ Bulk Powder Enclosures, Labconco®

Supplier: Labconco

Bulk powder enclosures keep airborne particulates and fumes contained during powder transfer operations

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Axygen® Gel Documentation Systems, Corning

Axygen® Gel Documentation Systems, Corning

Supplier: Corning

Axygen® gel documentation systems easily capture publication quality, 16 bit TIFF images. The systems are quick to set up and have an intuitive user interface for image capture, annotation, and contrast adjustment. Images are easily saved and opened in common gel analysis software for more detailed analysis.

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Eppendorf® New Brunswick™ Innova® 44/44R Stackable Incubator Shakers

Eppendorf® New Brunswick™ Innova® 44/44R Stackable Incubator Shakers

Supplier: Eppendorf

The Innova 44 and 44R (refrigerated) are Eppendorf’s most popular shakers - they accommodate flasks up to 5 L, have the space-saving glide-up door, and the reliable Innova triple-eccentric drive. They just run forever to give you peace of mind.

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PHCbi MDF Series –30 and −40 °C Biomedical ECO Upright Freezers, PHC Corporation

PHCbi MDF Series –30 and −40 °C Biomedical ECO Upright Freezers, PHC Corporation

Supplier: PHC Corporation

PHCbi Biomedical ECO Freezers provide a stable and reliable environment for storage of enzymes, vaccines, pharmaceutical products and other biomedical materials with uniform temperatures.

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SeroCP RT C. pneumoniae IgG ELISA Assay Kit, Eagle Biosciences, Inc.

Supplier: Eagle Biosciences

SeroCP IgG (RT) ELISA is intended to detect IgG aB specific to C

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pNLCoI4[luc2-P2A-NlucP/PGK/Hygro] Vector, 20 µg, Promega

pNLCoI4[luc2-P2A-NlucP/PGK/Hygro] Vector, 20 µg, Promega

Supplier: Promega Corporation

The pNLCoI Vectors comprise a second-generation coincidence reporter vector system that allow expression of both firefly luciferase (luc2) and NanoLuc Luciferase fused to a PEST destabilization domain (NlucP) from the same mRNA transcript.

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pGL4.43[luc2P/XRE/Hygro] Vector, 20 µg, Promega

pGL4.43[luc2P/XRE/Hygro] Vector, 20 µg, Promega

Supplier: Promega Corporation

These seven reporter vectors contain response elements (ARE, p53 RE, AT6 RE, MRE, HSE, HRE and XRE) that are important in various stress signaling pathways, the firefly luciferase gene and hygromycin resistance for selection in cells.

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pGL4.41[luc2P/HSE/Hygro] Vector, 20 µg, Promega

pGL4.41[luc2P/HSE/Hygro] Vector, 20 µg, Promega

Supplier: Promega Corporation

These seven reporter vectors contain response elements (ARE, p53 RE, AT6 RE, MRE, HSE, HRE and XRE) that are important in various stress signaling pathways, the firefly luciferase gene and hygromycin resistance for selection in cells.

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L(-)-Proline, powder for SILAC

Supplier: Invitrogen

Thermo Scientific Heavy and Light Amino Acids are used to specifically analyze protein expression by mass spectrometry using stable isotope labeling with amino acids in cell culture (SILAC) quantification kits.

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Amersham QuickStain Protein Labeling Kit, Cytiva

Amersham QuickStain Protein Labeling Kit, Cytiva

Supplier: Cytiva

The Amersham™ QuickStain Kit contains a Cy™5 fluorophore and labeling buffer for easy detection of proteins in SDSPAGE gels and on Western blotting membranes. The ready to use Cy5 N-hydroxysuccinimide (NHS) ester and Tris labeling buffer ensure robust and consistent labeling for detection of proteins in diverse samples.

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Anti-ERK2 Rabbit Polyclonal Antibody

Supplier: Bioss

The protein encoded by this gene is a member of the MAPkinase family. MAP kinases, also known as extracellularsignal-regulated kinases (ERKs), act in a signaling cascade thatregulates various cellular processes such as proliferation,differentiation, and cell cycle progression in response to avariety of extracellular signals. This kinase is activated byupstream kinases, resulting in its translocation to the nucleuswhere it phosphorylates nuclear targets. Alternatively splicedtranscript variants encoding different protein isoforms have beendescribed. [provided by RefSeq, Jul 2008].

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Static Mouse Cages, 1144B

Static Mouse Cages, 1144B

Supplier: Tecniplast Usa

The 1144B Mouse Cage can comfortably house 3 mice of standard size, and is available in polycarbonate or polysulfone materials.

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Urine Collection Tubes and Kits, BD Medical

Urine Collection Tubes and Kits, BD Medical

Supplier: BD

Urine collection tubes and kits are easy-to-use, and ideal for microbiology and urinalysis applications

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Ettan™ IPGphor™ 3 Isoelectric Focusing System, Cytiva

Ettan™ IPGphor™ 3 Isoelectric Focusing System, Cytiva

Supplier: Cytiva

Ettan™ IPGphor™ 3 is a fully integrated isoelectric focusing (IEF) system optimized to deliver high throughput, speed, reproducibility and high protein-loading capacity.

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Anti-PGR Mouse Monoclonal Antibody [clone: 608]

Anti-PGR Mouse Monoclonal Antibody [clone: 608]

Supplier: Prosci

There is accumulating evidence to suggest that progesterone plays an essential role in the regulation of growth and differentiation of mammary glands and thus may play a key role in breast cancer. The biological response to progesterone is mediated by two distinct forms of the human progesterone receptor (A and B forms). In most cell contexts, the B form functions as a transcriptional activator, whereas the A form functions as a transcriptional inhibitor of steroid hormones. Recently it has been demonstrated that there is differential hormone dependent regulation of the phosphorylation of the A and B forms of the receptor. Treatment of T47D breast cancer cells with progestin agonist increases the phosphorylation of Ser190 and Ser294 with different kinetics. These phosphorylation events may differentially affect the transcriptional activity of the receptor.

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ApoTox-Glo Triplex Assay, Promega

ApoTox-Glo Triplex Assay, Promega

Supplier: Promega Corporation

The ApoTox-Glo Triplex Assay combines three assay chemistries to easily assess viability, cytotoxicity and apoptosis events in the same cell-based assay well.

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Static Mouse Cages, 1145T

Static Mouse Cages, 1145T

Supplier: Tecniplast Usa

The 1145T Mouse cage can comfortably house four mice of standard size, and is available in polycarbonate or polysulfone materials.

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Blood genomicPrep Mini Spin Kits, Cytiva

Blood genomicPrep Mini Spin Kits, Cytiva

Supplier: Cytiva

The blood genomicPrep Mini Spin Kit is designed for the rapid and reproducible isolation of high-quality genomic DNA from whole blood, buffy coat, bone marrow, and nucleated red blood cells.

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Grid-Stick Kit, Electron Microscopy Sciences

Grid-Stick Kit, Electron Microscopy Sciences

Supplier: Electron Microscopy Sciences

The grid stick is coated with a specially-formulated pressure- sensitive adhesive.

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Eppendorf® 5702/5702 R/5702 RH Benchtop Centrifuge

Eppendorf® 5702/5702 R/5702 RH Benchtop Centrifuge

Supplier: Eppendorf

The range of Eppendorf 5702 general purpose, low-speed centrifuges has been designed specifically to meet the needs of mid-throughput clinical research and cell culture laboratories. These centrifuges are very compact, so that they fit easily on the laboratory bench, as well as extremely quiet.

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Elizabethkingia meningoseptica Recombinant N-Glycanase (PNGase F) (from E. coli)

Elizabethkingia meningoseptica Recombinant N-Glycanase (PNGase F) (from E. coli)

Supplier: AGILENT TECHNOLOGIES, INC (CSD)

AdvanceBio N-Glycanase (PNGase F), ≥2.5 U/mL (formerly ProZyme). A recombinant form of PNGase F, releases intact N-glycans by cleaving between the innermost GlcNAc and Asn. Includes 5x N-glycanase reaction buffer, denaturation solution, detergent solution, 5x N-glycanase Tris reaction buffer (MS applications). Supplied at a concentration of ≥ 2.5 U/mL. For a more concentrated formulation of ≥ 10 U/mL, which may be useful for native digestions, see GKE-5010B or GKE-5020B (EDTA-free).

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Anti-VEGF-A Recombinant Antibody [clone: Abz5]

Anti-VEGF-A Recombinant Antibody [clone: Abz5]

Supplier: Rockland Immunochemical

Humanized Recombinant Anti-VEGFA ScFV fragment Antibody has been tested for use in Flow Cytometry, Western Blot, and ELISA. This antibody recognizes structured VEGF-A and will work in western blot when the protein has not been denatured with DTT or bMe. Although not tested, this antibody could be useful in in IHC and in in-vivo and other cellular assays. Specific conditions for reactivity should be optimized by the end user

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GoTaq 2-Step RT-qPCR System, 5ml, Promega®

GoTaq 2-Step RT-qPCR System, 5ml, Promega®

Supplier: Promega Corporation

GoTaq RT-qPCR Systems are reagent systems for quantitative analysis of RNA. GoTaq qPCR Master Mix is a ready-to-use, stabilized 2X formulation containing GoTaq(R) Hot Start Polymerase, MgCl2, dNTPs, BRYT Green(R) Dye and a proprietary reaction buffer.

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Anti-GRIN2B Rabbit Polyclonal Antibody

Anti-GRIN2B Rabbit Polyclonal Antibody

Supplier: Prosci

The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s, epilepsy and ischemic neuronal cell death. Overexpression of the NR2B subunit of the receptor has been associated with increases in learning and memory while aged, memory impaired animals have deficiencies in NR2B expression. Tyr1472 on NR2B is phosphorylated and this may lead to the increased expression of the NMDAR at the synapse that plays a role in synaptic plasticity.

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Pierce™ HA-Tag Magnetic IP/Co-IP Kit, Thermo Scientific

Supplier: Invitrogen

The Pierce™ HA-Tag Magnetic IP/Co-IP Kit contains specific immunoaffinity magnetic beads and reagents to perform immunoprecipitation assays of HA fusion proteins or co-IP experiments using HA-tagged bait proteins.

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CryoStar™ NX50 Cryostats

CryoStar™ NX50 Cryostats

Supplier: Epredia

The CryoStar™ NX50 Cryostat extends the benefits of the NX series by offering an innovative new look at cryosectioning. The NX series has been designed completely around the user to deliver optimal sectioning quality, unmatched ergonomics, and safety in an energy efficient package. With the NX series, users can deliver high quality results comfortably, safely, and efficiently.

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VWR® Advanced Dura-Shaker for Extreme Environments

VWR® Advanced Dura-Shaker for Extreme Environments

Supplier: VWR International

The VWR® Dura-Shakers are designed for a wide range of applications including cell cultures that require CO₂ and humidity for optimal cell growth. The remote control module is designed to sit outside of the incubator. The thin ribbon cable is 5.5 feet (168 cm) long and easily passes underneath incubator door or through incubators utility port (minimum diameter 1.2” (3 cm). Controller magnetically attaches to most incubator doors or can sit on a lab bench.

   Sustainable Options Available
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VWR® Advanced Dura-Shaker for Extreme Environments, 230 V

VWR® Advanced Dura-Shaker for Extreme Environments, 230 V

Supplier: VWR International

The VWR® Dura-Shakers are designed for a wide range of applications including cell cultures that require CO₂ and humidity for optimal cell growth. The remote control module is designed to sit outside of the incubator. The thin ribbon cable is 5.5 feet (168 cm) long and easily passes underneath incubator door or through incubators utility port (minimum diameter 1.2” (3 cm). Controller magnetically attaches to most incubator doors or can sit on a lab bench.

   Sustainable Options Available
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VWR® Advanced Mini Dry Block Heater and Mini Dry Block Heater with Heated Lid, 120 V

VWR® Advanced Mini Dry Block Heater and Mini Dry Block Heater with Heated Lid, 120 V

Supplier: VWR International

VWR® Advanced Mini Dry Block Heaters and Mini Dry Block Heaters with Heated Lid are ideal for a variety of applications that require accurate and repeatable results such as LAMP assays, immunoassays, enzyme reactions, and denaturations.

   Sustainable Options Available
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Q qPCR Instrument, Quantabio

Q qPCR Instrument, Quantabio

Supplier: Quantabio

A faster, smaller, better way to qPCR

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