12044 Results for: "3-[5-(Chloromethyl)-1,2,4-oxadiazol-3-yl]-4-methoxybenzoic acid"

Supplier: LGC Standards

TRC Direct Brown 95 (Technical Grade)

Supplier: BBA

These cheesecloth wipes have an ideal absorbent surface for applying a uniform, thin film of gum arabic to an offset plate.

Supplier: Novus Biologicals

The BNIP3 Antibody (ANa40) [DyLight 488] from Novus Biologicals is a mouse monoclonal antibody to BNIP3. This antibody reacts with human. The BNIP3 Antibody (ANa40) [DyLight 488] has been validated for the following applications: Western Blot, ELISA, Immunocytochemistry / Immunofluorescence.

Supplier: TCI America

CAS Number: 3056-17-5
MDL Number: MFCD00132921
Molecular Formula: C10H12N2O4
Molecular Weight: 224.22
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 166
Specific rotation [a]20/D: -46 deg (C=0.69, H2O)

Supplier: TCI America

CAS Number: 37839-81-9
MDL Number: MFCD00069736
Molecular Formula: C10H12N5O6P
Molecular Weight: 351.19
Purity/Analysis Method: >98.0% (HPLC)
Form: Crystal

Supplier: MP Biomedicals

Urea is the principal end product of nitrogen metabolism in most mammals, formed by the enzymatic reactions of the Kreb's cycle.
Urea is a mild agent usually used in the solubilization and denaturation of proteins. It is also useful for renaturing proteins from samples already denatured with 6 M guanidine hydrochloride such as inclusion bodies; and in the extraction of the mitochondrial complex. It is commonly used to solubilize and denature proteins for denaturing isoelectric focusing and two-dimensional electrophoresis and in acetic acid-urea PAGE gels. Urea is used in cell or tissue culture media to increase the osmolality. Urea has also been used as fertilizer because of the easy availability of nitrogen; in animal feeds; it is reacted with aldehydes to make resins and plastics; condensed with malonic ester to form barbituric acid; used in the paper industry to soften cellulose; used as a diuretic; enhances the action of sulfonamides; an antiseptic.
Urea in solution is in equilibrium with ammonium cyanate. The form that reacts with protein amino groups is isocyanic acid. Urea in the presence of heat and protein leads to carbamylation of the proteins. Carbamylation by isocyanic acid interferes with protein characterization because isocyanic acid reacts with the amino terminus of proteins, preventing N-terminal sequencing. Isocyanic acid also reacts with side chains of lysine and arginine residues resulting in a protein that is unsuitable for many enzymatic digests. In addition, carbamylation often leads to confusing results from peptides having unexpected retention times and masses. When performing enzymatic protein digests it is important to remove urea first. Even though some enzymes will tolerate small amounts of urea, the elevated temperature used for most reactions will lead to carbamylation during the course of the digest. The urea can be removed prior to digestion by fast reversed phase chromatography, spin columns, or dialysis.
Dissolve urea in deionized water to the desired concentration.For every 10 ml of solution, add 1 g of Amberlite® IRA-910.Stir for one hour at room temperature

Supplier: TCI America

CAS Number: 3094-09-5
MDL Number: MFCD00866530
Molecular Formula: C9H11FN2O5
Molecular Weight: 246.19
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 189
Specific rotation [a]20/D: 20 deg (C=1, H2O)

Supplier: Invitrogen

Thermo Scientific EZ-Link Hydrazide-Biotin is the shortest and simplest hydrazide-activated biotinylation reagent for labeling glycoproteins and other carbohydrate-containing compounds having oxidizable sugars or aldehydes.

Supplier: TCI America

CAS Number: 50-91-9
MDL Number: MFCD00006530
Molecular Formula: C9H11FN2O5
Molecular Weight: 246.19
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 150
Specific rotation [a]20/D: 38 deg (C=1, H2O)

Supplier: Ohaus

The Valor® 4000 water-resistant food scale sets a new industry standard with the winning combination of touchless operations, speed, and durability

Supplier: TCI America

CAS Number: 35895-70-6
MDL Number: MFCD00042585
Molecular Formula: C17H36F3NO3S
Molecular Weight: 391.53
Purity/Analysis Method: >97.0% (T)
Form: Crystal
Color: White
Melting point (°C): 113

Supplier: Rockland Immunochemical

Vinculin is a cytoskeletal protein that plays an important role in the regulation of focal adhesions and embryonic development (1). Three structural vinculin domains include an amino-terminal head, a short flexible proline-rich region and a carboxy-terminal tail (2). Expression of vinculin were shown to be affected by the level of actin expression (2,3). Vinculin deficiencies are associated with a decrease in cell adhesion and an increase in cell motility, suggesting a possible role in metastatic growth (4). Defects in VCL are the cause of cardiomyopathy dilated type 1W (CMD1W) (5).

Supplier: Rockland Immunochemical

Vinculin is a cytoskeletal protein that plays an important role in the regulation of focal adhesions and embryonic development (1). Three structural vinculin domains include an amino-terminal head, a short flexible proline-rich region and a carboxy-terminal tail (2). Expression of vinculin were shown to be affected by the level of actin expression (2,3). Vinculin deficiencies are associated with a decrease in cell adhesion and an increase in cell motility, suggesting a possible role in metastatic growth (4). Defects in VCL are the cause of cardiomyopathy dilated type 1W (CMD1W) (5).

Supplier: Rockland Immunochemical

Vinculin is a cytoskeletal protein that plays an important role in the regulation of focal adhesions and embryonic development (1). Three structural vinculin domains include an amino-terminal head, a short flexible proline-rich region and a carboxy-terminal tail (2). Expression of vinculin were shown to be affected by the level of actin expression (2,3). Vinculin deficiencies are associated with a decrease in cell adhesion and an increase in cell motility, suggesting a possible role in metastatic growth (4). Defects in VCL are the cause of cardiomyopathy dilated type 1W (CMD1W) (5).

Supplier: Rockland Immunochemical

The sterol regulatory element binding transcription factor 2 (SREBF2) is a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis (1,2). The related protein SREBF1 also binds SRE1 and activates transcription in an additive fashion to SREBF2 (2). SREBF2 has been more closely associated with cholesterol synthesis and accumulation, while the SREBF1 proteins are important in the regulation of genes involved in lipid metabolism (3).

Supplier: TCI America

(stabilized with MEHQ)
CAS Number: 17096-07-0
MDL Number: MFCD00053871
Molecular Formula: C16H38O5Si4
Molecular Weight: 422.82
Purity/Analysis Method: >98.0% (GC)
Form: Clear Liquid
Boiling point (°C): 115
Flash Point (°C): 200
Specific Gravity (20/20): 0.93

Supplier: TCI America

CAS Number: 2096-10-8
MDL Number: MFCD00053556
Molecular Formula: C10H14N6O4
Molecular Weight: 282.26
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 252
Specific rotation [a]20/D: -40 deg (C=1, 0.1mol/L HCl)

Supplier: TCI America

[Reagent for Ion-Pair Chromatography]
CAS Number: 1643-19-2
MDL Number: MFCD00011633
Molecular Formula: C16H36BrN
Molecular Weight: 322.38
Purity/Analysis Method: >99.0% (T)
Form: Crystal
Melting point (°C): 103

Supplier: Thermo Scientific Chemicals

A non-nutritive sweetener and dipeptide ester about 160 times sweeter than sucrose.

Supplier: TCI America

CAS Number: 1576-85-8
MDL Number: MFCD00008723
Molecular Formula: C7H12O2
Molecular Weight: 128.17
Purity/Analysis Method: >98.0% (GC)
Form: Clear Liquid
Boiling point (°C): 151
Flash Point (°C): 45
Specific Gravity (20/20): 0.91

Supplier: Prosci

TEM5 Antibody: Tumor endothelial markers (TEMs) are significantly up-regulated during angiogenesis and neoangiogensis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies. These include TEMs such as TEM1, TEM5, TEM7 and TEM8. TEM5 is a member of the adhesion family of G protein coupled receptors and is localized on the surface of endothelial cells. TEM5 is a seven-pass transmembrane receptor, unlike TEM1, TEM7 and TEM8 which span the membrane once. TEM5 is abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon. Proteolytically processed soluble TEM5 mediates endothelial cell survival during angiogenesis by linking integrin to glycosaminoglycans.

Supplier: Prosci

TEM5 Antibody: Tumor endothelial markers (TEMs) are significantly up-regulated during angiogenesis and neoangiogensis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies. These include TEMs such as TEM1, TEM5, TEM7 and TEM8. TEM5 is a member of the adhesion family of G protein coupled receptors and is localized on the surface of endothelial cells. TEM5 is a seven-pass transmembrane receptor, unlike TEM1, TEM7 and TEM8 which span the membrane once. TEM5 is abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon. Proteolytically processed soluble TEM5 mediates endothelial cell survival during angiogenesis by linking integrin to glycosaminoglycans.

Supplier: TCI America

CAS Number: 2353-33-5
MDL Number: MFCD00043011
Molecular Formula: C8H12N4O4
Molecular Weight: 228.21
Form: Crystal
Color: White
Melting point (°C): 191
Specific rotation [a]20/D: 68.5 deg (C=0.5, H2O)
Storage Temperature: 0-10°C

Supplier: Rockland Immunochemical

NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP14 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP14, it has been suggested that it may play a role in spermatogenesis and that mutations in the NALP14 gene might cause spermatogenic failure.

Supplier: TCI America

[Reagent for Ion-Pair Chromatography]
CAS Number: 1112-67-0
MDL Number: MFCD00011635
Molecular Formula: C16H36ClN
Molecular Weight: 277.92
Purity/Analysis Method: >98.0% (T)
Form: Crystal
Melting point (°C): 70
Flash Point (°C): 113

Supplier: Abcam

HRP Rat monoclonal [YL1/2] to Tubulin - Loading Control.

Supplier: CLOUD-CLONE CORP MS

This assay has high sensitivity and excellent specificity for detecting Human BAFF (B-Cell Activating Factor). The assay range is from 78 to 5000 pg/ml (Sandwich kit) with a sensitivity of 29 pg/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.

Supplier: Thermo Scientific Chemicals

Inhibits chemically induced carcinogenesis in mouse skin and kidney

Supplier: Invitrogen

Thermo Scientific EZ-Link Hydrazide-LC-Biotin is a mid-length, simple, hydrazide-activated biotinylation reagent for labeling glycoproteins and other carbohydrate-containing compounds having oxidizable sugars or aldehydes.

Supplier: Rockland Immunochemical

ZEB1, initially identified as the delta-crystallin enhancer binding protein delta EF1, is a DNA-binding protein that binds to a modified E-box sequence and has been implicated in postgastrulation embryogenesis. ZEB1 binds to the promoter of several hemapoietic genes, including interleukin-2, CD4, GATA-3, and alpha-integrin, and mice in which ZEB1 has been targeted show thymic atrophy, and severe defects in lymphocyte differentiation. Recent evidence suggests that ZEB1 also regulates the accumulation of adipose tissue and may play a role in obesity. Mutations in this gene have been associated with late-onset Fuchs endothelial corneal dystrophy.