Supplier: Rockland Immunochemical

Tissue factor pathway inhibitor (TFPI), also known as lipoprotein-associated coagulation inhibitor, is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation (1). TFPI is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop (1).

Supplier: MCR Safety

Whether working in the rugged oil and gas industry or spending the day working near electrical hazards, stay safe and comfortable in FR gear made with Max Comfort™ fabrics.

Supplier: Prosci

LMIR1, also termed CD300a, is a type I transmembrane glycoprotein with a single IgV-like extracellular domain and an extended membrane proximal region that links the immunoglobulin (Ig) and transmembrane domains and belongs to the immunoglobulin superfamily. The intracellular domain of LMIR1 contains several immunoreceptor tyrosine-based inhibition motifs (ITIMs). When cross-linked, it will be tyrosine phosphorylated and capable of recruiting tyrosine phosphatases (SHP-1, SHP-2) and inositol polyphosphate 5-phosphatase, SHIP. LMIR1 will regulate mast cell-mediated inflammatory responses. LMIR1 is broadly expressed on myeloid and lymphoid cells, and its expression is differentially regulated depending on the cell type.

Supplier: Invitrogen

The Thermo Scientific Pierce Conjugate Purification Kit is a gentle affinity chromatography system for purifying horseradish peroxidase (HRP) or alkaline phosphatase (AP) conjugated antibodies from unreacted enzyme after labeling.

Supplier: Rockland Immunochemical

LRRK2 is a large protein with multiple domains including several ankyrin, leucine-rich, and WD40 repeats, a Ras-like small GTPase family domain named Roc, and a kinase domain that is closely related to the RIP kinase domain. LRRK2 gene is expressed in brain as well as in other tissues such as lung, liver and heart. LRRK2 might be central to the pathogenesis of several major neurodegenerative diseases associated with parkinsonism. Several dominantly inherited missense mutations in the gene encoding LRRK2 have been identified in several families that exhibit a broad spectrum of neuropathological features. Anti-LRRK2 is ideal for researchers interested in Neuroscience, specifically parkinsonism, as well as pathways related to the Electron Transport Chain and Wnt Signaling.

Supplier: Thermo Fisher Scientific

Thermo Scientific™ TSX Series high-performance -20°C manual defrost freezers offer a sustainable choice for clinical and laboratory storage.

Supplier: Bioss

CLUAP1 (Clusterin associated protein 1) is a 413 amino acid nuclear protein that exists as two alternatively spliced isoforms that interact with Clusterin. CLUAP1 is suggested to play a role in apoptosis and cell proliferation, and is expressed in testis, thrachea and thyroid, with low levels found in adrenal gland and spinal cord. The gene encoding CLUAP1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

Supplier: DRG International

An enzyme immunoassay for the qualitative and semiquantitative determination of IgM-class antibodies to Epstein-Barr virus nuclear-1 antigen (EBV-EBNA-1) in serum.

Supplier: Eppendorf

Eppendorf epT.I.P.S.® Racks feature high-precision pipette tips in 'Eppendorf Quality', 'PCR clean', 'Biopur®', and 'Sterile' purity grades. All tips are supplied in disposible racks designed for optimal organization and user convenience in demanding laboratory environments.

Supplier: MCR Safety

Whether working in the rugged oil and gas industry or spending the day working near electrical hazards, stay safe and comfortable in FR gear made with Max Comfort™ fabrics.

Supplier: Leica Microsystems

The Leica Ivesta 3 stereo microscope offers precise optics and user-friendly features, enhancing sorting tasks in labs. With advanced capabilities, it streamlines processes, providing reliable and efficient results. Elevate your workflow with the convenience of the Leica Ivesta 3 microscope.

Supplier: ROEMER INDUSTRIES, INC.

PharmaRoam8 is a medical-grade, countertop refrigerator or freezer that has optional accessories such as battery power and data management. Designed to transport vaccines and pharmaceuticals, units function as refrigerators or freezers down to 1 °C (optional −20 °C with refrigerant change) and run on a battery while on the move. These units can be secured with a padlock, have handles on the side and can be stacked with stacking corners. Excellent for disaster preparedness to store temperature sensitive products when the electrical power supply is not reliable or dependable.

Supplier: ATM

Next-generation sonic sifter capable of quickly achieving dry particle separations ranging from 5.6 mm to 3 µm.

Supplier: Prosci

Slc35D1 Antibody: The solute carrier family Slc35 consists of at least 17 proteins that act as nucleotide sugar transporters localized to the Golgi apparatus and endoplasmic reticulum. The role of the ER-resident Slc family member Slc35D1 is to transport both UDP-glucuronic acid and UDP-N-acetylgalactosamine. These molecules can serve as substrates for chondroitin sulfate biosynthesis and mice lacking the Slc35D1 gene developed a lethal form of skeletal dysplasia with severe shortening of limbs and facial structures. Examination of epiphyseal cartilage in these mice revealed a decreased proliferating zone with round chrondrocytes, scarce matrices, and reduced proteoglycan aggregates. Loss of function mutations in human Slc35D1 cause Schneckenbecken dysplasia, a severe skeletal dysplasia.

Supplier: Greiner Bio-One

Tubes are designed for routine use in immunohematology testing and viral marker testing in screening and clinical laboratories.

Supplier: Eagle Biosciences

Vaspin ELISA is to be used in the determination of the Vaspin in the serum samples.

Supplier: Justrite

This Double Cylinder Hand Truck with Firewall and Hoist Ring provides safety when moving and storing of gas cylinders.

Supplier: POWERBLANKET LLC MS

Powerbanket IBC tote warmers offer cutting-edge technology for freeze protection, chemical storage, and viscosity control in a flexible, easy-to-install design that will effectively, evenly, and reliably heat your IBC tote. Our patented design eliminates hot and cold spots by applying uniform full-coverage heat across the entire surface of the container, allowing users to keep their materials at the proper viscosity while remaining at specified thermal levels. Each tote heater can be equipped with either an adjustable or an IoT smart thermostat. Tote heaters come in two voltages: 120 volts and 240 volts.

Supplier: Promega Corporation

FLT3 is a receptor tyrosine kinase that has been shown to play a role in proliferation and survival of hematopoietic progenitor cells as well as differentiation of early B lymphoid progenitors.

Supplier: Promega Corporation

The Heater Shaker Magnet Instrument (HSM 2.0) performs all the functions necessary for the processing of magnetic resin-based purification chemistries in large-volume formats.

Supplier: VWR International

This microscope is a live cell microscope platform for advanced microbiology. The instrument can be upgraded with Fluorescence for research tasks, while the 'Light memory' function and the Auto ON/OFF mode enables a fast and safe throughput of samples.

Supplier: MCR Safety

Whether working in the rugged oil and gas industry or spending the day working near electrical hazards, stay safe and comfortable in FR gear made with Max Comfort™ fabrics.

Supplier: MCR Safety

These coveralls are manufactured from a comfortable 88% cotton/12% nylon twill material.

Supplier: Siemens Healthineers

CLINITEK® Advantus® Urine Chemistry Analyzer from Siemens Healthcare Diagnostics provides automated reading of the Multistix® family of urinalysis tests.

Supplier: Promega Corporation

The HaloTag Technology enables covalent protein labeling and immobilization in vivo and in vitro.

Supplier: Air Science

Purair® PCR laminar flow cabinets employ the Air Science® Multiplex™ HEPA filtration technology to create a safe, energy-efficient contaminant-free environment. These PCR workstations are ideally suited for use with non-hazardous contaminants and when flexible access to the instrumentation in the cabinet is required.

Supplier: Rockland Immunochemical

The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT4 localizes to mitochondria, inhibits glutamate dehydrogenase, and is thought to be involved in the regulation of insulin secretion.

Supplier: YMC America,Inc

YMC-Triart C18, 3 µm is a novel, organic/inorganic hybrid silica particle derivatized with C18 (L1 USP designation).

Supplier: Labconco

Racks and supports hold test tubes, flasks and microwell plates for pre-freezing and freeze drying samples; clear canister holds chemical traps.

Supplier: BLICKMAN INDUSTRIES

Warming cabinets are constructed with quality 304 stainless steel, #4 polish and have a seamless welded face preventing dirt collection while providing long lasting durability through unparalleled strength and corrosion resistance. This line of warming cabinets includes single chamber, dual chamber, tabletop, under-counter, and recessed models (including a pass-through version with doors on the front and back).