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38712 results for "3,5-Dimethyl-4-methoxy-2-pyridinemethanol"

38712 Results for: "3,5-Dimethyl-4-methoxy-2-pyridinemethanol"

Anti-TSPY1 Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical

Testis-specific protein on Y chromosome (TSPY1) is an ampliconic gene on the Y chromosome that has been associated with gonadoblastoma. Recent experiments have shown that in androgen-dependent testicular germ-cell tumors, TSPY1 can repress the androgen-bound androgen receptor (AR), a member of the nuclear steroid hormone receptor family that acts as a ligand-inducible transcription factor, suggesting that TSPY1 is a repressor of cell proliferation in germ-cell tumors and potentially in normal gonadal cells during early development. Two distinct isoforms of TSPY1, TSPY1L and TSPY1S, are known to exist.

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Anti-TSPY1 Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical

Testis-specific protein on Y chromosome (TSPY1) is an ampliconic gene on the Y chromosome that has been associated with gonadoblastoma. Recent experiments have shown that in androgen-dependent testicular germ-cell tumors, TSPY1 can repress the androgen-bound androgen receptor (AR), a member of the nuclear steroid hormone receptor family that acts as a ligand-inducible transcription factor, suggesting that TSPY1 is a repressor of cell proliferation in germ-cell tumors and potentially in normal gonadal cells during early development. Two distinct isoforms of TSPY1, TSPY1L and TSPY1S, are known to exist.

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P450-Glo™ CYP2D6 Screening System, 1000 Assays, Promega

P450-Glo™ CYP2D6 Screening System, 1000 Assays, Promega

Supplier: Promega Corporation

The P450-Glo Screening Systems provide a complete set of reagents for performing luminescent cytochrome P450 assays

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Anti-SLC35D1 Rabbit Polyclonal Antibody

Anti-SLC35D1 Rabbit Polyclonal Antibody

Supplier: Prosci

Slc35D1 Antibody: The solute carrier family Slc35 consists of at least 17 proteins that act as nucleotide sugar transporters localized to the Golgi apparatus and endoplasmic reticulum. The role of the ER-resident Slc family member Slc35D1 is to transport both UDP-glucuronic acid and UDP-N-acetylgalactosamine. These molecules can serve as substrates for chondroitin sulfate biosynthesis and mice lacking the Slc35D1 gene developed a lethal form of skeletal dysplasia with severe shortening of limbs and facial structures. Examination of epiphyseal cartilage in these mice revealed a decreased proliferating zone with round chrondrocytes, scarce matrices, and reduced proteoglycan aggregates. Loss of function mutations in human Slc35D1 cause Schneckenbecken dysplasia, a severe skeletal dysplasia.

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Anti-SLC39A11 Rabbit Polyclonal Antibody

Anti-SLC39A11 Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical

ZIP11, also known as Slc39A11, is a member of the broader ZIP family of multi-transmembrane domain metal ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Members of the ZIP family generally transport metal ions from the cell exterior or lumen of intracellular organelles into the cytoplasm, as opposed to the ZnT (SLC30) family of zinc transporters that serve to reduce intracellular zinc availability by promoting zinc efflux from cells or into intracellular vesicles. At least three isoforms of ZIP11 are known to exist.

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Anti-SPP1 Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical

The secreted protein 1 (SPP1), also known as osteopontin, is a major noncollagenous protein of bone, but is also found in the extracellular matrix of other mineralized tissues and in bodily fluids. In bone, SPP1 is produced by osteoblasts, osteocytes, macrophages, and osteoclasts (1,2). SPP1 binds to cells through integrin and non-integrin receptors, as well as the adhesion receptor CD44 in an RGD-independent manner, enabling SPP1 to induce a number of functional effects including macrophage chemotaxis, cytoprotection, and regulation of T helper type 1 cells (2). SPP1 can regulate biomineralization by inhibiting the formation of hydroxyapatite (3) and the growth of calcium oxalate crystals (4).

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Anti-phospholamban Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Supplier: Bioss

The Sarco(endo)plasmic-reticulum (SER) regulatory protein, Phospholamban (PLB), is a small, plasma membrane-associated protein found in the SER of cardiac, smooth and slow-twitch muscle. Believed to assemble into a pentamer, PLB regulates cardiac contractility and Ca2+ affinity for cardiac SER Ca2+ ATPase (SERCA2a). Non-phosphorylated PLB associates with SERCA2a, and inhibits Ca2+ reuptake into the SER. PLB activation occurs when key Serine/Threonine residues in PLB (Ser-10, Ser-16, Thr-17) are phosphorylated by numerous effectors, which include PKC, PKA, PKG, and CaM kinase. Phosphorylation of PLB causes dissociation from SERCA2a and a subsequent increase in the rate of Ca2+ reuptake into the SER, which accelerates ventricular relaxation.

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YMC-Triart C18 Hybrid Silica HPLC Columns; C18, 5 µm, Analytical, YMC America

YMC-Triart C18 Hybrid Silica HPLC Columns; C18, 5 µm, Analytical, YMC America

Supplier: YMC America,Inc

YMC-Triart C18, 5 µm is a novel, organic/inorganic hybrid silica particle derivatized with C18 (L1 USP designation).

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Whatman™ Cellulose Chromatography Papers

Whatman™ Cellulose Chromatography Papers

Supplier: Cytiva

Whatman chromatography papers are widely used across the world, reflecting their purity, high quality and consistency. They are made from specially selected cotton cellulose and rigorously quality controlled to ensure uniformity within the grade.

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DRG® EBV-VCA IgM ELISA, DRG International, Inc.

DRG® EBV-VCA IgM ELISA, DRG International, Inc.

Supplier: DRG International

An enzyme immunoassay for the qualitative and semiquantitative determination of IgM-class antibodies to Epstein-Barr viral capsid antigen in human serum.

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AimStrip® Urine Analyzer II, Germaine Laboratories

AimStrip® Urine Analyzer II, Germaine Laboratories

Supplier: Germaine Laboratories

The AimStrip® Urine Analyzer 2 reads urine test strips, stores results and prints reports, all without the need for special training.

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Anti-TFPI Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical

Tissue factor pathway inhibitor (TFPI), also known as lipoprotein-associated coagulation inhibitor, is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation (1). TFPI is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop (1).

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Flame Resistant Insulated Bomber Jackets, MCR Safety

Supplier: MCR Safety

Whether working in the rugged oil and gas industry or spending the day working near electrical hazards, stay safe and comfortable in FR gear made with Max Comfort™ fabrics.

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Mouse Recombinant LMIR1

Supplier: Prosci

LMIR1, also termed CD300a, is a type I transmembrane glycoprotein with a single IgV-like extracellular domain and an extended membrane proximal region that links the immunoglobulin (Ig) and transmembrane domains and belongs to the immunoglobulin superfamily. The intracellular domain of LMIR1 contains several immunoreceptor tyrosine-based inhibition motifs (ITIMs). When cross-linked, it will be tyrosine phosphorylated and capable of recruiting tyrosine phosphatases (SHP-1, SHP-2) and inositol polyphosphate 5-phosphatase, SHIP. LMIR1 will regulate mast cell-mediated inflammatory responses. LMIR1 is broadly expressed on myeloid and lymphoid cells, and its expression is differentially regulated depending on the cell type.

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VWR® Microscopes with Camera Bundle, Inverted Trinocular Microscopes with 4K built-in 11.6" LCD Screen HDMI Camera

VWR® Microscopes with Camera Bundle, Inverted Trinocular Microscopes with 4K built-in 11.6" LCD Screen HDMI Camera

Supplier: VWR International

This microscope is a live cell microscope platform for advanced microbiology. The instrument can be upgraded with Fluorescence for research tasks, while the 'Light memory' function and the Auto ON/OFF mode enables a fast and safe throughput of samples.

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P450-Glo CYP1A2 Induction/Inhibition Assay, Promega

P450-Glo CYP1A2 Induction/Inhibition Assay, Promega

Supplier: Promega Corporation

The P450-Glo CYP1A2 Assay and Screening Systems provide a complete set of reagents for performing luminescent cytochrome P450 assays

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P450-Glo CYP2C19 Screening System, Promega

P450-Glo CYP2C19 Screening System, Promega

Supplier: Promega Corporation

The P450-Glo Screening Systems provide a complete set of reagents for performing luminescent cytochrome P450 assays

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P450-Glo CYP2B6 Screening System, Promega

P450-Glo CYP2B6 Screening System, Promega

Supplier: Promega Corporation

The P450-Glo Screening Systems provide a complete set of reagents for performing luminescent cytochrome P450 assays

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Double Cylinder Hand Truck with Firewall and Hoist Ring, Justrite®

Double Cylinder Hand Truck with Firewall and Hoist Ring, Justrite®

Supplier: Justrite

This Double Cylinder Hand Truck with Firewall and Hoist Ring provides safety when moving and storing of gas cylinders.

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Powerblanket® IBC Tote Heaters

Supplier: POWERBLANKET LLC MS

Powerbanket IBC tote warmers offer cutting-edge technology for freeze protection, chemical storage, and viscosity control in a flexible, easy-to-install design that will effectively, evenly, and reliably heat your IBC tote. Our patented design eliminates hot and cold spots by applying uniform full-coverage heat across the entire surface of the container, allowing users to keep their materials at the proper viscosity while remaining at specified thermal levels. Each tote heater can be equipped with either an adjustable or an IoT smart thermostat. Tote heaters come in two voltages: 120 volts and 240 volts.

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ADP-Glo Kinase Assay + FLT3 Kinase Enzyme System, 1 each, Promega

ADP-Glo Kinase Assay + FLT3 Kinase Enzyme System, 1 each, Promega

Supplier: Promega Corporation

FLT3 is a receptor tyrosine kinase that has been shown to play a role in proliferation and survival of hematopoietic progenitor cells as well as differentiation of early B lymphoid progenitors.

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HSM 2.0 Instrument, Promega

HSM 2.0 Instrument, Promega

Supplier: Promega Corporation

The Heater Shaker Magnet Instrument (HSM 2.0) performs all the functions necessary for the processing of magnetic resin-based purification chemistries in large-volume formats.

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MB120 Halogen Moisture Analyzer, OHAUS

MB120 Halogen Moisture Analyzer, OHAUS

Supplier: Ohaus

The MB120 delivers functionality and precision that you can rely on, and is easy to operate and clean—you can test more samples in less time! Advanced features such as a temperature guide help to analyze optimum drying temperature, and methods and results storage allows statistical analysis of measurements. Three levels of user management ensure data safety—set up and lock temperature settings and method parameters with administrator access.

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Pierce™ Conjugate Purification Kit, Thermo Scientific

Pierce™ Conjugate Purification Kit, Thermo Scientific

Supplier: Invitrogen

The Thermo Scientific Pierce Conjugate Purification Kit is a gentle affinity chromatography system for purifying horseradish peroxidase (HRP) or alkaline phosphatase (AP) conjugated antibodies from unreacted enzyme after labeling.

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Anti-LRRK2 Mouse Monoclonal Antibody [Clone: S138-6]

Supplier: Rockland Immunochemical

LRRK2 is a large protein with multiple domains including several ankyrin, leucine-rich, and WD40 repeats, a Ras-like small GTPase family domain named Roc, and a kinase domain that is closely related to the RIP kinase domain. LRRK2 gene is expressed in brain as well as in other tissues such as lung, liver and heart. LRRK2 might be central to the pathogenesis of several major neurodegenerative diseases associated with parkinsonism. Several dominantly inherited missense mutations in the gene encoding LRRK2 have been identified in several families that exhibit a broad spectrum of neuropathological features. Anti-LRRK2 is ideal for researchers interested in Neuroscience, specifically parkinsonism, as well as pathways related to the Electron Transport Chain and Wnt Signaling.

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TSK-Gel® Reversed Phase Columns, Tosoh Bioscience

TSK-Gel® Reversed Phase Columns, Tosoh Bioscience

Supplier: Tosoh Bioscience

These silica- and polymer-based columns are ideal for reversed-phase applications such as pharmaceutical drugs, forensic compounds, derivatised amino acids, carbohydrates, steroids, lipids and fatty acids. Depending on their molecular weight, peptides may be analysed with the 80 to 140 Å silica-based columns, while proteins require a larger pore size column (200 to 300 Å).

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BioFit® MVMT™ Tech Series Critical Performance Seating, Technical Performance Package, BioFit

BioFit® MVMT™ Tech Series Critical Performance Seating, Technical Performance Package, BioFit

Supplier: BioFit

Represents a revolutionary advancement in technical ergonomic seating and is changing the user experience dynamic in today’s workplace. This seating combines a forward-looking European perspective with the tradition of technological precision and proven durability.

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Anti-APE Rabbit Polyclonal Antibody

Supplier: Genetex

Mammalian apurinic/apyrimidinic endonuclease (APE/ref-1) is a multifunctional, bipartite enzyme that plays an important role in numerous, cellular functions. APE is responsible for repairing abasic sites in DNA and in regulating the redox state of other proteins that play roles in oxidative signaling, transcription factor regulation (Fos, Jun, NFkB, Myb, HIF1 alpha, CREB, Pax), cell cycle control (p53), and apoptosis. Altered levels of APE have also been found in some cancers. The most common form of DNA damage is the creation of abasic sites which are brought about through spontaneous loss or oxidative DNA damage, through chemically initiated hydrolysis (chemotherapy), ionizing radiation, UV irradiation, oxidizing agents, and removal of modified bases by DNA glycosylases.

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VACUETTE® Serum Clot Activator Tubes, Greiner Bio-One

VACUETTE® Serum Clot Activator Tubes, Greiner Bio-One

Supplier: Greiner Bio-One

Tubes are designed for routine use in immunohematology testing and viral marker testing in screening and clinical laboratories.

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VASPIN ELISA, Eagle Biosciences

Supplier: Eagle Biosciences

Vaspin ELISA is to be used in the determination of the Vaspin in the serum samples.

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