Supplier: Biotium

TRAcP (Tartarate Resistant Acid Phosphatase), Monoclonal antibody, Clone: ACP5/1070, Host: Mouse, Species reactivity: Mouse, Rat, Human, Isotype: IgG2b, kappa, Conjugate: CF488A, Immunogen: Recombinant full-length human ACP5 protein, Application: IF, Flow cytometry, Size: 100uL

Supplier: Desco

Statshield® Smock Jacket with Snaps are a groundable static control garment system.

Supplier: Antyila Scientific

Variable speed mixer designed for reliability and durability.

Supplier: Prosci

TRIM35 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. TRIM35 may play a role as a tumor suppressor, and is implicated in the cell death mechanism.The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this protein has not been identified.

Supplier: Promega Corporation

FLT3 is a receptor tyrosine kinase that has been shown to play a role in proliferation and survival of hematopoietic progenitor cells as well as differentiation of early B lymphoid progenitors.

Supplier: Electron Microscopy Sciences

Hot plates with rugged low profile cast aluminum body and ceramic or aluminum top plate.

Supplier: ANTIBODIES.COM LLC

Human CD134/OX40L receptor ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human CD134/OX40L receptor in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Biotium

TRAcP (Tartarate Resistant Acid Phosphatase), Monoclonal antibody, Clone: ACP5/1070, Host: Mouse, Species reactivity: Mouse, Rat, Human, Isotype: IgG2b, kappa, Conjugate: CF568, Immunogen: Recombinant full-length human ACP5 protein, Application: IF, Flow cytometry, Size: 500uL

Supplier: NABERTHERM INC.

These Muffle furnaces stand out for their excellent workmanship, advanced and attractive design, and high level of reliability. Heating elements on support tubes radiating freely into the furnace chamber provide particularly short heating times and a maximum temperature of 1400 °C. These models are a good alternative to the familiar L(T) ../11 series when higher application temperatures are needed.

Supplier: Electron Microscopy Sciences

Top of the Line Features a warning system deters accidental contact with hot surface.

Supplier: Leica Microsystems

The Leica MZ10-F stereo microscope is a state-of-the-art instrument for precise microscopic observation. Its advanced optics and ergonomic design make it a smart choice for sorting. With exceptional image quality and versatility, the MZ10-F improves efficiency and accuracy in life sciences research.

Supplier: YMC America,Inc

YMC-Triart C8, 5µm is a novel organic/inorganic hybrid silica particle derivatized with C8 (L7 USP designation).

Supplier: Protexer

The KineticButler Shoe Cover Dispenser is designed for low, moderate, or high volume areas where speed, safety, and compliance are critical. The simple design allows booties to be applied hands-free and enables workers to enter facilities without dropping tools or touching dirty shoes. Dispensers are available in two sizes. The large unit has a handle for safety and stability while applying shoe covers, while the small unit is more easily transported. Both units require no electricity for operation.

Supplier: Prosci

CD300A is a single-pass type I membrane protein that belongs to the CD300 family. CD300A consists of a 163 amino acid (aa) extracellular domain (ECD) with one Ig-like V- type domain, a 21 amino acid transmembrane segment, and a 98 amino acid cytoplasmic domain with tyrosine residues. CD300A is expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. CD300A is an inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation.

Supplier: Epredia

The Epredia™ HM 525 NX series of Cryostats offer exceptional sectioning quality and reliability, an intuitive user interface, and enhanced ergonomics for simple, efficient operation.

Supplier: Biotium

CD74 Monoclonal antibody, Clone: BU45, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF405S, Immunogen: B lymphoblastoid cell line HFB1Unigene 436568, Application: Immunofluorescence, Western, Flow cytometry, Size: 100uL

Supplier: Prosci

The Galectin family of proteins (with specificity for Nacetyllactosamine containing glycoproteins) consists of beta-galactoside binding lectins containing homologous carbohydrate recognition domains (CRDs). At least 14 mammalian galectins family members that share structural similarities in their carbohydrate recognition domains (CRD) have been identified to date. Unlike the selectin family of proteins, the carbohydrate binding specificity of galectins is calcium-independent. A common function of galectins is to cross-link structures containing N-acetyl-lactosamine located at the cell surface and within the extracellular matrix. They also possess hemagglutination activity, which is attributable to their bivalent carbohydrate binding properties. Galectins are active both intracellularly and extracellularly. They have diverse effects on many cellular functions including adhesion, migration, polarity, chemotaxis, proliferation, apoptosis, and differentiation. Galectins may therefore play a key role in many pathological states, including autoimmune diseases, allergic reactions, inflammation, tumor cell metastasis, atherosclerosis, and diabetic complications. The galectins have been classified into the prototype galectins (1, 2, 5, 7, 10, 11, 13, 14), which contain one CRD and exist either as a monomer or a noncovalent homodimer. The chimera galectins (Galectin3) containing one CRD linked to a nonlectin domain, and the tandem repeat Galectins (4, 6, 8, 9, 12) consisting of two CRDs joined by a linker peptide. Galectins lack a classical signal peptide and can be localized to the cytosolic compartments where they have intracellular functions. However, via one or more as yet unidentified nonclassical secretory pathways, galectins can also be secreted to function extracellularly. Individual members of the galectin family have different tissue distribution profiles and exhibit subtle differences in their carbohydrate-binding specificities. Each family member may preferentially bind to a unique subset of cell surface glycoproteins.

Supplier: Janitorial Supplies

Four-stage hospital-type filtration that effectively cleans air in small spaces. The Smart Sensor detects air quality and automatically adjusts the fan speed to keep air purified.

Supplier: WORLD PRECISION INSTRUMENTS LLC

WPI’s improved precision SurgioScope (now with five magnification steps) is a portable high quality surgical
microscope offering outstanding image quality and value. Incorporating an agile extension arm and excellent working distance objectives, the SurgioScope provides convenient movement and maneuverability necessary for accurate positioning. These important features, together with a high quality optical system, provide sharp image contrast and enhanced large field of vision. The SurgioScope comes fully equipped with a foot-controlled motorized focusing system, normally only found in more expensive surgical microscopes.

Supplier: WORLD PRECISION INSTRUMENTS LLC

DAM Series amplifiers are well known as a standard of the industry for extracellular potential amplification. These battery powered bio-amplifiers are designed with a compact chassis profile that enables you locate the unit closer to the preparation and thereby minimize long lead lengths which contribute to noise. Each amplifier is equipped with selectable high and low filters, and a position control to offset galvanic potentials which may develop during recording.

Supplier: Bioss

CLUAP1 (Clusterin associated protein 1) is a 413 amino acid nuclear protein that exists as two alternatively spliced isoforms that interact with Clusterin. CLUAP1 is suggested to play a role in apoptosis and cell proliferation, and is expressed in testis, thrachea and thyroid, with low levels found in adrenal gland and spinal cord. The gene encoding CLUAP1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

Supplier: Biotium

TRAcP (Tartarate Resistant Acid Phosphatase), Monoclonal antibody, Clone: ACP5/1070, Host: Mouse, Species reactivity: Mouse, Rat, Human, Isotype: IgG2b, kappa, Conjugate: CF405S, Immunogen: Recombinant full-length human ACP5 protein, Application: IF, Flow cytometry, Size: 100uL

Supplier: Rockland Immunochemical

Testis-specific protein on Y chromosome (TSPY1) is an ampliconic gene on the Y chromosome that has been associated with gonadoblastoma. Recent experiments have shown that in androgen-dependent testicular germ-cell tumors, TSPY1 can repress the androgen-bound androgen receptor (AR), a member of the nuclear steroid hormone receptor family that acts as a ligand-inducible transcription factor, suggesting that TSPY1 is a repressor of cell proliferation in germ-cell tumors and potentially in normal gonadal cells during early development. Two distinct isoforms of TSPY1, TSPY1L and TSPY1S, are known to exist.

Supplier: Rockland Immunochemical

Testis-specific protein on Y chromosome (TSPY1) is an ampliconic gene on the Y chromosome that has been associated with gonadoblastoma. Recent experiments have shown that in androgen-dependent testicular germ-cell tumors, TSPY1 can repress the androgen-bound androgen receptor (AR), a member of the nuclear steroid hormone receptor family that acts as a ligand-inducible transcription factor, suggesting that TSPY1 is a repressor of cell proliferation in germ-cell tumors and potentially in normal gonadal cells during early development. Two distinct isoforms of TSPY1, TSPY1L and TSPY1S, are known to exist.

Supplier: Rockland Immunochemical

The proline-rich transmembrane protein 2 (PRRT2) contains a proline-rich domain in its N-terminal half and is predominantly expressed in brain and spinal cord in embryonic and postnatal stages. While little is known of the function of this protein, mutations in PRRT2 have been shown to be the causative gene of paroxysmal kinesigenic dyskinesia, which is characterized by recurrent, brief attacks of abnormal involuntary movements induced by sudden voluntary movements. Recent studies have shown that PRRT2 may also be involved in some forms of benign familial infantile epilepsy (BFIE), an autosomal dominant epilepsy syndrome.

Supplier: Promega Corporation

The P450-Glo CYP1A2 Assay and Screening Systems provide a complete set of reagents for performing luminescent cytochrome P450 assays

Supplier: Greiner Bio-One

Designed for use in the examination of coagulation parameters, coagulation tubes contain a buffered tri-sodium citrate solution.

Supplier: Desco

Statshield® Smock Jacket with Knitted Cuffs is a groundable static control garment system.

Supplier: Bioss

The Sarco(endo)plasmic-reticulum (SER) regulatory protein, Phospholamban (PLB), is a small, plasma membrane-associated protein found in the SER of cardiac, smooth and slow-twitch muscle. Believed to assemble into a pentamer, PLB regulates cardiac contractility and Ca2+ affinity for cardiac SER Ca2+ ATPase (SERCA2a). Non-phosphorylated PLB associates with SERCA2a, and inhibits Ca2+ reuptake into the SER. PLB activation occurs when key Serine/Threonine residues in PLB (Ser-10, Ser-16, Thr-17) are phosphorylated by numerous effectors, which include PKC, PKA, PKG, and CaM kinase. Phosphorylation of PLB causes dissociation from SERCA2a and a subsequent increase in the rate of Ca2+ reuptake into the SER, which accelerates ventricular relaxation.

Supplier: Promega Corporation

Recombinant human FLT3 (D835Y) (571-993) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.