57659 Results for: "2-Bromo-5-fluoro-4-nitropyridine+1-oxide"

Supplier: Promega Corporation

These seven reporter vectors contain response elements (ARE, p53 RE, AT6 RE, MRE, HSE, HRE and XRE) that are important in various stress signaling pathways, the firefly luciferase gene and hygromycin resistance for selection in cells.

Supplier: Genetex

FluoroGel is an aqueous-based mounting medium designed for the preservation of fluorescence-stained tissue sections.

Supplier: Saint Gobain Life Sciences

PharMed® BPT is designed to maintain fluid integrity during fluid transport. Transporting biocompatible fluids through a peristaltic pump limits the risk of fluid contact with any portion of the pump itself. PharMed® BPT tubing has been formulated to withstand the rigors of peristaltic pumping action while providing the biocompatible fluid surface required in sensitive applications.

Supplier: Restek

Restek Rt®-Alumina BOND columns are highly selective for C1 to C5 hydrocarbons and separate all saturated and unsaturated hydrocarbon isomers above ambient temperatures.

Supplier: Restek

Restek Rt®-Alumina BOND columns are highly selective for C1 to C5 hydrocarbons and separate all saturated and unsaturated hydrocarbon isomers above ambient temperatures.

Supplier: Promega Corporation

HaloTag Ligand Building Blocks are designed for use with HaloTag fusion proteins and can carry a variety of functionalities, including fluorescent labels, affinity tags and attachments to a solid phase.

Supplier: Invitrogen

Hoechst 33342 fluorescent stain is a high-quality solution of Hoechst dye for fixed- and live-cell fluorescent staining of DNA and nuclei in cellular imaging techniques.

Supplier: Promega Corporation

HaloTag Ligand Building Blocks are designed for use with HaloTag fusion proteins and can carry a variety of functionalities, including fluorescent labels, affinity tags and attachments to a solid phase.

Supplier: MP Biomedicals

Bovine albumin is a single polypeptide chain consisting of approximately 583 to 595 amino acid residues and no carbohydrates. At pH 5-7 it contains 17 intrachain disulfide bridges and 1 sulfhydryl group.

Supplier: MP Biomedicals

Ferritin, Equine is a shell of 24 protein subunits (apoferritin) and a core Fe 3+ ions with a peptide MW of 440 kDa. Review of the ferritin-like superfamily of iron-storage proteins, virtually ubiquitous in life on earth.
A ubiquitous iron storage protein that plays a key role in iron metabolism. It serves as an intracellular iron reserve (particularly in spleen, liver, intestinal mucosa, and bone marrow) and functions in iron detoxification. Studies have shown that ferritin iron incorporation is mediated by a ferroxidase activity associated with ferritin H subunits and a nucleation center associated with ferritin L subunits. Release of iron from ferritin has an essential role in iron-dependent lipid peroxidation and may contribute to free radical-induced cell damage in vivo. Therefore, by binding iron, ferritin may function as an antioxidant.
Store at +4 °C.

Supplier: VWR International

Our VWR® laboratory-grade water purification systems feature an inspiring, application-oriented design. Perform your workflows faster and more reliably, simplifying your daily lab work while ensuring cost-efficient operation over the long term. All instruments offer flexible solutions as they can be adapted to your requirements and integrated into your laboratory environment.

Supplier: Restek

Contains 1 ml each of the followig mixtures, 8270 calibration mix #1, 8270 calibration mix #2, 8270 calibration mix #3, 8270 calibration mix #4, 8270 calibration mix #5 revised and 3-methylcholanthrene standard.

Supplier: BTNX INC.

The Rapid Response™ Fentanyl test strips (Liquid/Powder) detects fentanyl in suspicious substances on surfaces and liquids from suspicious receptables at a cut-off concentration of 200 ng/ml.

Supplier: Thermo Fisher Scientific

Designed to achieve your next breakthrough. Better solutions for optimal cell growth, VIOS CO₂ incubators provide the ideal in-vitro environment.

Supplier: ELGA LabWater

The PURELAB® flex range is designed to deliver accuracy, flexibility and ease-of-use. The award-winning system provides perfect water purity for analytical and life science applications which require RO type III water up to ultrapure type I (18.2 MΩ.cm) water. It allows focus on routine test work without concern about the water quality affecting test results.

Supplier: SLICE, INC.

Spring-loaded automatic blade retraction is just one of the features that makes the Slice® Auto-Retractable Slim Pen Cutter a safer choice. Slice’s proprietary grind—applied to advanced ceramics—creates the only finger-friendly® blade on the market. In addition, our blades never rust and last up to 11 times longer than comparable metal blades. This pen cutter’s durable glass-filled nylon handle has a slim design that’s ideal for working in tight spaces. As with all Slice tools, it can be configured for either right-handed or left-handed use and requires no tools to change the blade.

Supplier: Invitrogen

Thermo Scientific Pierce TCEP-HCl is a potent, versatile, odorless, thiol-free reducing agent with broad application to protein and other research involving reduction of disulfide bonds. The unique compound is easily soluble and very stable in many aqueous solutions. TCEP reduces disulfide bonds as effectively as dithiothreitol (DTT), but unlike DTT and other thiol-containing reducing agents, TCEP does not have to be removed before certain sulfhydryl-reactive crosslinking reactions.

Supplier: LGC Standards

Organic Standard, 4-iso-Octylphenol-ethoxylate (technical)

Supplier: LGC Standards

TRC IGEPAL CA-630

Supplier: TCI America

CAS Number: 1119-34-2
MDL Number: MFCD00064550
Molecular Formula: C6H14N4O2
Molecular Weight: 210.66
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 235
Specific rotation [a]20/D: 23 deg (C=8, HCl(1+1))

Supplier: SLICE, INC.

The Slice® Manual Slim Pen Cutter uses the same finger-friendly® blade as our original pen cutters, offering the same safety benefits. Slice’s proprietary grind—applied to advanced ceramics—creates a unique edge that’s safe to the touch and lasts up to 11 times longer than comparable metal blades. The slim handle style allows maneuverability in tight spaces and features a side slider for easier manipulation with the thumb. As with all Slice tools, it can be used ambidextrously. Made from durable glass-filled nylon, the Manual Slim Pen Cutter offers two different cutting depths to suit a variety of cutting tasks.

Supplier: Thermo Fisher Scientific

Designed to achieve your next breakthrough. Better solutions for optimal cell growth, VIOS CO₂ incubators provide the ideal in-vitro environment.

Supplier: MP Biomedicals

IPTG (isopropyl-β-thiogalactoside) is an analogue of allolactose that binds specifically to the repressor protein of the lac operon and induces expression of β-galactosidase in Escherichia coli.
IPTG is a commonly used reagent in cloning procedures that require induction of b-galactosidase activity and is used in conjunction with X-Gal in blue-white color selection of recombinant bacterial colonies.
The final concentration typically used in indicator plates is 0.2 mM.

Supplier: BTNX INC.

The Rapid Response™ Fentanyl (FYL) forensic test kit is a lateral flow chromatographic immunoassay for the qualitative detection of fentanyl in liquid and powder substances at the cut-off concentration of 200 ng/ml.

Supplier: Biosensis

Black-Gold II is a novel haloaurophosphate complex which localises myelin within the central nervous system. The Black Gold II Ready-to-Dilute (RTD) Staining Kit allows you to localise myelin, both individual fibres and tracts, along with the option of co-localising cell bodies via the Toluidine Blue counter stain. Black Gold II labelled myelinated fibres appear nearly black while the Toluidine Blue O labelled cellular Nissl bodies are blue under bright field illumination.

Supplier: MP Biomedicals

Storage: Store at +4 °C, store under nitrogen
Glutathione is the major low molecular weight thiol compound of the living plant or animal cell. It is a tripeptide with a gamma peptide linkage between the amine group of cysteine (which is attached by normal peptide linkage to a glycine) and the carboxyl group of the glutamate side-chain. It is an antioxidant, preventing damage to important cellular components caused by reactive oxygen species such as free radicals and peroxides. The sulfhydryl (thiol) group (SH) of cysteine serves as a proton donor and is responsible for the biological activity of glutathione.
Glutathione suppresses human immunodeficiency virus expression in chronically infected monocytic cells. It is a useful tripeptide involved in many aspects of metabolism, including transport of g-glutanyl amino acids and reductive cleavage of disulfide bonds.
Endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center. Glutathione also forms disulfide bonds with cysteine residues in proteins. Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.

Supplier: MP Biomedicals

The FastRNA™ Spin Kit isolates both large and small RNA species without the use of phenol or reducing agents.

Supplier: MP Biomedicals

Folic acid, also known as folate, is a B vitamin that can be found in a variety of fruits and vegetables. It can also be chemically synthesized. Folate, a watersoluble vitamin, helps the body form red blood cells and aids in the formation of genetic material within every body cell. This product exhibits metal binding properties. Hematopoietic vitamin present, free or combined with one or more additional molecules of L-(+)-glutamic acid, in liver, kidney, mushrooms, spinach, yeast, green leaves, and grasses.
Folic acid (Vitamin B9 and folate) is essential to numerous bodily functions. The human body needs folate to synthesize DNA, repair DNA, and methylate DNA as well as to act as a cofactor in certain biological reactions. It is especially important in aiding rapid cell division and growth, such as in infancy and pregnancy.
Folic acid (FA) and dihydrofolic acid (FAH2) are substrates of dihydrofolate reductase(s) which reduce them to tetrahydrofolate (THF), which in turn supports ‘one carbon’ transfer. Tetrahydrofolates are required for de novo synthesis of purines, thymidylic acid and various amino acids and for post-translational methylation (epigenetics).
Very slightly soluble in cold water (0.0016 mg/mL at 25 °C), soluble to about 1% in boiling water. Slightly soluble in methanol, appreciably less soluble in ethanol and butanol. Insoluble in acetone, chloroform, ether, benzene. Relatively soluble in acetic acid, phenol, pyridine, solutions of alkali hydroxides and carbonates. Soluble in hot dilute HCl and H2SO4.

Supplier: MP Biomedicals

Protein kinase C inhibitor (IC50 = 50-200 µM depending on assay conditions in MCF-7 cells or IC50 = 100 µM in rat brain). The PKC inhibition is also dependent on the phosopholipid concentration. Also inhibits both calmodulin-dependent and calmodulin-independent Ca2+-, Mg2+-ATPase. Tamoxifen is a selective estrogen response modifier (SERM), anti-angiogenetic factor. It is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells.
Tamoxifen has been used to facilitate the recombination of ect2flox allele in mouse organs. It has also been used to study its effect on lipopolysaccharide (LPS)-induced microglial activation
Tamoxifen is a Protein kinase C inhibitor. It induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.