145279 Results for: "2-Benzyloxy-5-pyrimidineboronic+acid"

Supplier: Promega Corporation

Recombinant full-length human CHK1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. CHK1 was originally identified in fission yeast to play a role in activation of the DNA damage checkpoint in the G2 phase of the cell cycle.

Supplier: Promega Corporation

ACK is a tyrosine kinase that binds CDC42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of CDC42Hs.

Supplier: Bioss

Receptor for GABA. The activity of this receptor is mediated by G-proteins that inhibit adenylyl cyclase activity, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipids hydrolysis. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA-B-R inhibit neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA-B-R decrease neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception.

Supplier: Bioss

In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA ) and metabotropic (GABAB ) receptors as well as a third class of receptors called GABAC. In addition to GABA receptors, several proteins have been identified as regulators of GABA function, including GAD65, GAD67, GABA transporters and GABARAP (GABAA receptor-associated protein). GABARAP associates with GABAA Rg2 to link GABAA receptors to the cytoskeleton. The GABARAP protein sequence is similar to light chain-3 of microtubule-associated proteins (MAPs) suggesting that it may be a type of MAP or a component of a MAP complex.

Supplier: Bioss

In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA ) and metabotropic (GABAB ) receptors as well as a third class of receptors called GABAC. In addition to GABA receptors, several proteins have been identified as regulators of GABA function, including GAD65, GAD67, GABA transporters and GABARAP (GABAA receptor-associated protein). GABARAP associates with GABAA Rg2 to link GABAA receptors to the cytoskeleton. The GABARAP protein sequence is similar to light chain-3 of microtubule-associated proteins (MAPs) suggesting that it may be a type of MAP or a component of a MAP complex.

Supplier: Antibodies.com

Human Cross Linked C-telopeptide of Type II Collagen CTXII ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human Cross Linked C-telopeptide of Type II Collagen CTXII in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Antibodies.com

Rat CaMKII beta ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of rat CaMKII beta in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Antibodies.com

Human Cross Linked C-telopeptide of Type I Collagen/CTXI ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human Cross Linked C-telopeptide of Type I Collagen/CTXI in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Antibodies.com

Rabbit Cross Linked N-telopeptide of Type I Collagen/NTXI ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of rabbit Cross Linked N-telopeptide of Type I Collagen/NTXI in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Antibodies.com

Mouse N-Terminal Propeptide of Collagen alpha-1(I) Chain/PINP ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of mouse N-Terminal Propeptide of Collagen alpha-1(I) Chain/PINP in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Antibodies.com

Rat G-Protein Coupled receptor 30 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of rat G-Protein Coupled receptor 30 in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Antibodies.com

Monkey Cross Linked C-telopeptide of Type I Collagen/CTXI ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of monkey Cross Linked C-telopeptide of Type I Collagen/CTXI in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Antibodies.com

Human N-Terminal Propeptide of Collagen alpha-1(IV) Chain/PIVNP ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human N-Terminal Propeptide of Collagen alpha-1(IV) Chain/PIVNP in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Antibodies.com

Human CaMKII alpha ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human CaMKII alpha in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Novus Biologicals

IL-33, also known as NF-HEV and DVS 27, is a 30 kDa proinflammatory protein that may also regulate gene transcription (1‑3).

Supplier: Novus Biologicals

IL-33, also known as NF-HEV and DVS 27, is a 30 kDa proinflammatory protein that may also regulate gene transcription (1‑3).

Supplier: Antibodies.com

Porcine C-terminal Propeptide of Collagen alpha-1(I) Chain/PICP ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of porcine C-terminal Propeptide of Collagen alpha-1(I) Chain/PICP in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Antibodies.com

Mouse cAMP Protein Kinase Catalytic Subunit alpha ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of mouse cAMP Protein Kinase Catalytic Subunit alpha in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Antibodies.com

Human PGC1 alpha ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human PGC1 alpha in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Antibodies.com

Rabbit Cross Linked C-telopeptide of type I Collagen/CTXI ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of rabbit Cross Linked C-telopeptide of type I Collagen/CTXI in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Antibodies.com

Mouse NF-kB p65 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of mouse NF-kB p65 in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Bioss

The Vang family of proteins are integral membrane proteins that are homologues of the Drosophila tissue polarity gene strabismus. The gene encoding for Van Gogh-like protein 1 (Vangl1), also designated Strabismus 2 (STB2), localizes to human chromosome 1p11-p13.1. Van Gogh-like protein 2 (Vangl2), also designated Strabismus 1 (STB1), localizes to chromosome 1q22-q23. Vangl1 is expressed primarily in testis and ovary, but is also expressed in gastric and pancreatic cancer. Vangl proteins play a key developmental role in establishing planar cell polarity (PCP) and in regulating convergent extension (CE) movements during embryogenesis. Vangl1 and Vangl2 are both downregulated in several cancer cell lines and primary tumors.

Supplier: Bioss

The Vang family of proteins are integral membrane proteins that are homologues of the Drosophila tissue polarity gene strabismus. The gene encoding for Van Gogh-like protein 1 (Vangl1), also designated Strabismus 2 (STB2), localizes to human chromosome 1p11-p13.1. Van Gogh-like protein 2 (Vangl2), also designated Strabismus 1 (STB1), localizes to chromosome 1q22-q23. Vangl1 is expressed primarily in testis and ovary, but is also expressed in gastric and pancreatic cancer. Vangl proteins play a key developmental role in establishing planar cell polarity (PCP) and in regulating convergent extension (CE) movements during embryogenesis. Vangl1 and Vangl2 are both downregulated in several cancer cell lines and primary tumors.

Supplier: WORLD PRECISION INSTRUMENTS LLC

The A385 is an optically isolated current source, which can generate up to 100 mA of unipolar or biphasic constant current pulses or DC. Pulse duration is controlled manually or by an external 5 V command. Output current amplitude is determined by a 3-digit 10-turn potentiometer. Maximum output voltage between the stimulating electrodes is +36 V.

Supplier: Labconco

Specifically designed to rapidly concentrate multiple small heat-sensitive samples using centrifugal force, vacuum, and controlled temperature.

Supplier: MP Biomedicals

Proteinase K is a highly active stable endopeptidase with a broad spectrum of action was isolated by E. Merk's Darmstadt Biochemical Research Department in 1970 from a culture filtrate of the fungus, Tritirachium album Limber. This fungus is able to grow on Keratin (e.g., wool, horn particles) as the sole source of carbon and nitrogen. The isolated protease was, therefore, given the K designation.

Supplier: Bioss

Receptor for GABA. The activity of this receptor is mediated by G-proteins that inhibit adenylyl cyclase activity, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipids hydrolysis. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA-B-R inhibit neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA-B-R decrease neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception.

Supplier: Bioss

Receptor for GABA. The activity of this receptor is mediated by G-proteins that inhibit adenylyl cyclase activity, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipids hydrolysis. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA-B-R inhibit neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA-B-R decrease neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception.

Supplier: Promega Corporation

Recombinant full-length human CAMK2 alpha was expressed by baculovirus in Sf9 cells using an N-terminal GST tag. CAMK2 alpha is a ser/thr protein kinase that is a member of the Ca2+/calmodulin-dependent protein kinase family.

Supplier: Promega Corporation

Recombinant full-length human PKC epsilon was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. PKC epsilon is a member of the protein kinase C (PKC) family of serine- and threonine-specific protein kinases.