31450 Results for: "2,7-Di-tert-butylfluorene"
MEDICA® Water Purification Systems, ELGA LabWater
Supplier: ELGA LabWater
The MEDICA® range are designed to provide water to clinical analyzers specified to Clinical Laboratory Reagent Water (CLRW) standard, ranging from 1.8 to 21 liters/min (depending on unit selected).
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Anti-HSP25 + HSP27 Rabbit Polyclonal Antibody
Supplier: Enzo Life Sciences
Hsp27 is one of the most common members of the highly conserved and ubiquitously expressed family of small heat shock proteins (sHsp), which also includes alphaB-crystallin. It is characterized by a conserved C-terminal alpha-crystallin domain consisting of two anti-parallel beta-sheets that promote oligomer formation required for its primary chaperone function as inhibitor of irreversible protein aggregation. Hsp27 oligomerization is modulated by post-translational phosphorylation of Hsp27 at three serine residues, Ser15, Ser78, and Ser82, by a variety of protein kinases including MAPKAPK-3, PKAc-alpha, p70 S6K, PKD I, and PKC-delta. Hsp27 has been shown to inhibit actin polymerization by binding of unphosphorylated Hsp27 monomers to actin intermediate filaments. Anti-apoptotic functions of Hsp27 have also been identified through interactions with DAXX7, activation of Akt, and inhibition of apoptosome formation. Evidence suggests altered expression of Hsp27 is implicated in the pathogenesis of breast, ovarian, and prostate cancer.
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Protector® Workstations, Labconco®
Supplier: Labconco
Designed for the needs of histologists and pathologists, these workstations rid the lab of dangerous organic solvent fumes, such as formaldehyde and xylene, and restore clean air
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CryoCube® F101h Ultra-Low Temperature Freezer
Supplier: Eppendorf
The CryoCube® F101h ULT freezers offers a personal storage solution in a convenient package. The compact design means the unit will fit below a standard laboratory bench so samples are always securely close-at-hand. F101h has two inner compartments for storing for up to 6 racks/60 boxes giving space for up to 6000 vessels (1.5 ml). These freezers with efficient and reliable 2-stage compressor systems help reduce energy consumption, which helps to lower costs. Energy consumption: (–70/–80 ℃): 4.6/6.3 KWh/day.
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Bench Top Sterilizers, 230 V, Heidolph Tuttnauer
Supplier: Heidolph NA, LLC
Sterilizers provide a fast, safe, dependable, and convenient means of sterilizing wrapped, unwrapped, glass and tools. Not suitable for liquids or media (LabLine is suitable for liquids and media).
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Anti-BIRC8 Rabbit Polyclonal Antibody
Supplier: Rockland Immunochemical
Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family including IAP, XIAP/ILP-1/MIHA, and Livin/KIAP that bind to and inhibits specific proteases. A novel member in the IAP protein family was recently identified and designated ILP-2 for IAP-like protein-2. ILP-2 has high homology to ILP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues. ILP-2, unlike ILP-1, has no inhibitory effect on Fas and TNF induced apoptosis, but potently inhibits apoptosis induced by overexpression of Bax or by coexpression of caspase-9 with Apaf-1. ILP-2 interacts with the processed caspase-9. These results suggest that ILP-2 is a novel IAP family member with restricted specificity for caspase-9.
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Cell Systems Human Adult Dermal Microvascular Endothelial Cells, Primary Cell and Media Company
Supplier: Cell Systems
Our primary human cells offer unmatched consistency and a more biologically relevant tool than other cell types. Our cells are antibody-free and come from a deep inventory to help researchers with reproducibility and improved human insights.
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Cell Systems Human Venous Endothelial Cells (HUVEC), Primary Cell and Media Company
Supplier: Cell Systems
Our primary human cells offer unmatched consistency and a more biologically relevant tool than other cell types. Our cells are antibody-free and come from a deep inventory to help researchers with reproducibility and improved human insights.
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Cell Systems Human Aortic Smooth Muscle Cells, Primary Cell and Media Company
Supplier: Cell Systems
Our primary human cells offer unmatched consistency and a more biologically relevant tool than other cell types. Our cells are antibody-free and come from a deep inventory to help researchers with reproducibility and improved human insights.
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Cell Systems Human Coronary Artery Endothelial Cells, Primary Cell and Media Company
Supplier: Cell Systems
Our primary human cells offer unmatched consistency and a more biologically relevant tool than other cell types. Our cells are antibody-free and come from a deep inventory to help researchers with reproducibility and improved human insights.
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Cell Systems Human Aortic Endothelial Cells, Primary Cell and Media Company
Supplier: Cell Systems
Our primary human cells offer unmatched consistency and a more biologically relevant tool than other cell types. Our cells are antibody-free and come from a deep inventory to help researchers with reproducibility and improved human insights.
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Cell Systems Human Arterial Endothelial Cells, Primary Cell and Media Company
Supplier: Cell Systems
Our primary human cells offer unmatched consistency and a more biologically relevant tool than other cell types. Our cells are antibody-free and come from a deep inventory to help researchers with reproducibility and improved human insights.
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CryoStar™ NX50 Cryostats
Supplier: Epredia
The CryoStar™ NX50 Cryostat extends the benefits of the NX series by offering an innovative new look at cryosectioning. The NX series has been designed completely around the user to deliver optimal sectioning quality, unmatched ergonomics, and safety in an energy efficient package. With the NX series, users can deliver high quality results comfortably, safely, and efficiently.
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Cell Systems Human Synovial Stromal Cells, Primary Cell and Media Company
Supplier: Cell Systems
Our primary human cells offer unmatched consistency and a more biologically relevant tool than other cell types. Our cells are antibody-free and come from a deep inventory to help researchers with reproducibility and improved human insights.
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PURELAB® Chorus 3 Water Purification System, ELGA LabWater
Supplier: ELGA LabWater
When general laboratory grade water (Type III) is all you need, then PURELAB Chorus 3 is the reliable solution with the flexibility to suit your requirements.
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Cell Systems Human Coronary Artery Smooth Muscle Cells, Primary Cell and Media Company
Supplier: Cell Systems
Our primary human cells offer unmatched consistency and a more biologically relevant tool than other cell types. Our cells are antibody-free and come from a deep inventory to help researchers with reproducibility and improved human insights.
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Moxi™ Z Mini Automated Cell Counter
Supplier: Orflo
The Moxi™ Z automated cell counter combines the the “gold-standard” Coulter Principle typically used in high-end instruments with a patented thin-film sensor technology to provide highly accurate and repeatable direct cell/particle size and count over a broad dynamic range (2-34 microns), with single cell resolution
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Anti-CD82 Rabbit Polyclonal Antibody
Supplier: Rockland Immunochemical
KAI1 was initially identified from a T-cell activation study as a four-transmembrane protein that plays an accessory role in T-cell activation, and was later determined to act as a cancer metastasis suppressor gene. This protein is ubiquitously expressed at moderate to high levels in most tissues, but its expression is downregulated during tumor progression. The loss of KAI1 and p53 is associated with poor survival for prostate and other cancer patients. Recently, KAI1 was found to interact with DARC, the Duffy antigen for chemokines using a yeast two hybrid screen. It is thought that tumor cells dislodged from the primary tumor and expressing KAI1 interact with DARC proteins expressed on vascular cells, transmitting a senescent signal to the tumor cells, while tumor cells that have lost KAI1 expression can proliferate and potentially give rise to metastases. At least two isoforms of KAI1 are known to exist.
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XPert™ Filtered Balance Stations, Labconco®
Supplier: Labconco
These stations provide user protection by keeping powders and particulates contained during weighing procedures
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Cell Systems Human Brain Microvascular Endothelial Cells, Primary Cell and Media Company
Supplier: Cell Systems
Our primary human cells offer unmatched consistency and a more biologically relevant tool than other cell types. Our cells are antibody-free and come from a deep inventory to help researchers with reproducibility and improved human insights.
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Anti-EDA2R Rabbit Polyclonal Antibody
Supplier: Rockland Immunochemical
X-linked ectodysplasin-A2 receptor (XEDAR) is a recently isolated member of the tumor necrosis factor receptor family that is highly expressed during embryonic development and binds to ectodysplatin-A2 (EDA-A2). Two predominantly expressed isoforms, XEDAR-s and XEDAR-L, differ by only a 21-amino region at the juxtamembrane region of the cytoplasmic domain. Neither isoform possesses a death domain and both have been shown to act mainly through TRAF3 and TRAF6 to activate the NF-kB and JNK pathways. Cells transfected with XEDAR and treated with EDA-A2 cause the assembly of a secondary complex containing FADD, caspase-8 and caspase-10, leading to the activation caspase-8 and caspase-3, and finally apoptosis. The EDA-A2-induced apoptosis is dependent on caspase-9 activation, as various pharmacological and genetic inhibitors of caspase-8 blocked apoptosis following EDA-A2 treatment.
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Anti-HSP25 + HSP27 Rabbit Polyclonal Antibody
Supplier: Enzo Life Sciences
Hsp27 is one of the most common members of the highly conserved and ubiquitously expressed family of small heat shock proteins (sHsp), which also includes alphaB-crystallin. It is characterized by a conserved C-terminal alpha-crystallin domain consisting of two anti-parallel beta-sheets that promote oligomer formation required for its primary chaperone function as inhibitor of irreversible protein aggregation. Hsp27 oligomerization is modulated by post-translational phosphorylation of Hsp27 at three serine residues, Ser15, Ser78, and Ser82, by a variety of protein kinases including MAPKAPK-3, PKAc-alpha, p70 S6K, PKD I, and PKC-delta. Hsp27 has been shown to inhibit actin polymerization by binding of unphosphorylated Hsp27 monomers to actin intermediate filaments. Anti-apoptotic functions of Hsp27 have also been identified through interactions with DAXX7, activation of Akt, and inhibition of apoptosome formation. Evidence suggests altered expression of Hsp27 is implicated in the pathogenesis of breast, ovarian, and prostate cancer.
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Cell Systems Human Retinal Microvascular Endothelial Cells, Primary Cell and Media Company
Supplier: Cell Systems
Our primary human cells offer unmatched consistency and a more biologically relevant tool than other cell types. Our cells are antibody-free and come from a deep inventory to help researchers with reproducibility and improved human insights.
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Dimethyl sulfoxide for molecular biology
Supplier: MP Biomedicals
Storage: Room Temperature, desiccate, store under nitrogen.
Dimethyl Sulfoxide is a dipola, aprotic solvent. It has been shown to accelerate strand renaturation (1-10% concentration) and is believed to give the nucleic acid thermal stability against depurination.
Dimethyl Sulfoxide is used to enhance dermal absorption of many chemicals, as a solvent for many organic and inorganic compounds including fats, carbohydrates, dyes, resins, and polymers, in antifreeze or hydraulic fluids, as a cryopreservative for cell cultures, oxidation of thiols and disulfides to sulfonic acids, as a PCR cosolvent to help improve yields, especially in long PCR. DMSO is routinely used in polymerase chan reaction (PCR), amplification of cDNA libraries, DNA sequencing, column-loading buffers for poly (A)+ RNA selection, buffers for the transformation of competent E. coli, and transfection protocols.
To prepare sterile solutions use a teflon or nylon membrane to sterile-filter the DMSO - do not use a cellulose acetate membrane.
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Protector® XVS Ventilation Stations, Labconco®
Supplier: Labconco
This ventilated work area is ideal as a weighing station, light-duty fume hood, science classroom workstation, solvent cleaning work bay, or for veterinary pathology and cytology
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XPert™ Filtered Balance Systems, Labconco®
Supplier: Labconco
These portable systems provide user protection by keeping powders and particulates contained during weighing procedures
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Cell Systems Human Brain Pericytes, Primary Cell and Media Company
Supplier: Cell Systems
Our primary human cells offer unmatched consistency and a more biologically relevant tool than other cell types. Our cells are antibody-free and come from a deep inventory to help researchers with reproducibility and improved human insights.
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Anti-MED27 Rabbit Polyclonal Antibody
Supplier: Prosci
he activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. CRSP8 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. CRSP8 is also a component of other multisubunit complexes e.g. thyroid hormone receptor- (TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor- (TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
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Cell Systems Human Retinal Pericyte Cells, Primary Cell and Media Company
Supplier: Cell Systems
Our primary human cells offer unmatched consistency and a more biologically relevant tool than other cell types. Our cells are antibody-free and come from a deep inventory to help researchers with reproducibility and improved human insights.