25957 Results for: "2,5-Dichloro-4-pyridineboronic acid"

Supplier: Invitrogen

The Thermo Scientific Pierce Magnetic RNA-Protein Pull-Down Kit provides researchers with a streamlined, robust method to enrich protein-RNA interactions using end-labeled RNA as the bait.

Supplier: Globe Scientific

Globe Glass™ volumetric flasks are calibrated to meet ASTM tolerance specifications for precise measurement in solution preparation and dilution. A diamond etched graduation line indicates the calibrated capacity of each measuring flask. Wide mouth options are available for easier filling and mixing. Globe Glass™ volumetric flasks are offered in sizes ranging from 1 to 2000 ml, and with Class A or Class B calibration tolerances. Class A volumetric flasks include a batch calibration certificate.

Supplier: Genetex

Tau proteins are microtubule-associated proteins that are abundant in neurons in the central nervous system and are less common elsewhere. They were discovered in 1975 in Marc Kirschner's laboratory at Princeton University. Tau proteins interact with tubulin to stabilize microtubules and promote tubulin assembly into microtubules. Tau has two ways of controlling microtubule stability: isoforms and phosphorylation. Six tau isoforms exist in brain tissue, and they are distinguished by their number of binding domains. Three isoforms have three binding domains and the other three have four binding domains. The binding domains are located in the carboxy-terminus of the protein and are positively-charged (allowing it to bind to the negatively-charged microtubule). The isoforms with four binding domains are better at stabilizing microtubules than those with three binding domains. The isoforms are a result of alternative splicing in exons 2,3, and 10 of the tau gene. Phosphorylation of tau is regulated by a host of kinases. For example, PKN, a serine/threonine kinase. When PKN is activated, it phosphorylates tau, resulting in disruption of microtubule organization. Hyperphosphorylation of the tau protein (tau inclusions), however, can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease and other tauopathies. Tau protein is a highly soluble microtubule-associated protein (MAP). In humans, these proteins are mostly found in neurons compared to non-neuronal cells. One of tau's main functions is to modulate the stability of axonal microtubules. Tau is not present in dendrites and is active primarily in the distal portions of axons where it provides microtubule stabilization but also flexibility as needed. This contrasts with STOP proteins in the proximal portions of axons which essentially lock down the microtubules and MAP2 that stabilizes microtubules in dendrites. The tau gene locates on chromosome 17q21, containing 16 exons. The major tau protein in the human brain is encoded by 11 exons. Exon 2, 3 and 10 are alternative spliced, allowing six combinations (2-3-10-; 2+3-10-; 2+3+10-; 2-3-10+; 2+3-10+; 2+3+10+). Thus, in the human brain, the tau proteins constitute a family of six isoforms with the range from 352-441 amino acids. They differ in either no, one or two inserts of 29 amino acids at the N-terminal part (exon 2 and 3), and three or four repeat-regions at the C-terminal part exon 10 missing. So, the longest isoform in the CNS has four repeats (R1, R2, R3 and R4) and two inserts (441 amino acids total), while the shortest isoform has three repeats (R1, R3 and R4) and no insert (352 amino acids total). All of the six tau isoforms are present in an often hyperphosphorylated state in paired helical filaments from Alzheimer's Disease brain. In other neurodegenerative diseases, the deposition of aggregates enriched in certain tau isoforms has been reported. When misfolded this otherwise very soluble protein can form extremely insoluble aggregates that contribute to a number of neurodegenerative diseases.

Supplier: Proteintech

The THOC5 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human THOC5. This antibody recognizes human,mouse,rat antigen. The THOC5 antibody has been validated for the following applications: ELISA, IHC, WB, IF, IP analysis.

Supplier: Brady Worldwide

Indoor/outdoor safety signs from Brady® are available in a variety of materials, allowing users to choose the material and size that best fits any application.

Supplier: Globe Scientific

Produced from a custom grade low-density polyethylene (LDPE), these unbreakable one-piece pipettes are used to draw and dispense liquids in controlled, reproducible drop sizes.

Supplier: TCI America

CAS Number: 16423-68-0
MDL Number: MFCD00144257
Molecular Formula: C20H8I4O5
Molecular Weight: 879.86
Purity/Analysis Method: >95.0% (E)
Form: Crystal
Color: Yellow Red
Lambda max.: 526 nm (0.02mol/L AcONH4 sol.)

Supplier: CLOUD-CLONE CORP MS

This assay has high sensitivity and excellent specificity for detecting Human PLA2R1 (Phospholipase A2 Receptor 1). The assay range is from 0.156 to 10 ng/ml (Sandwich kit) with a sensitivity of 0.062 ng/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.

Supplier: ANTIBODIES.COM LLC

Human IGFBP3 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human IGFBP3 in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: ANTIBODIES.COM LLC

Human FABP4 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human FABP4 in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Genetex

Tau proteins are microtubule-associated proteins that are abundant in neurons in the central nervous system and are less common elsewhere. They were discovered in 1975 in Marc Kirschner's laboratory at Princeton University. Tau proteins interact with tubulin to stabilize microtubules and promote tubulin assembly into microtubules. Tau has two ways of controlling microtubule stability: isoforms and phosphorylation. Six tau isoforms exist in brain tissue, and they are distinguished by their number of binding domains. Three isoforms have three binding domains and the other three have four binding domains. The binding domains are located in the carboxy-terminus of the protein and are positively-charged (allowing it to bind to the negatively-charged microtubule). The isoforms with four binding domains are better at stabilizing microtubules than those with three binding domains. The isoforms are a result of alternative splicing in exons 2,3, and 10 of the tau gene. Phosphorylation of tau is regulated by a host of kinases. For example, PKN, a serine/threonine kinase. When PKN is activated, it phosphorylates tau, resulting in disruption of microtubule organization. Hyperphosphorylation of the tau protein (tau inclusions), however, can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease and other tauopathies. Tau protein is a highly soluble microtubule-associated protein (MAP). In humans, these proteins are mostly found in neurons compared to non-neuronal cells. One of tau's main functions is to modulate the stability of axonal microtubules. Tau is not present in dendrites and is active primarily in the distal portions of axons where it provides microtubule stabilization but also flexibility as needed. This contrasts with STOP proteins in the proximal portions of axons which essentially lock down the microtubules and MAP2 that stabilizes microtubules in dendrites. The tau gene locates on chromosome 17q21, containing 16 exons. The major tau protein in the human brain is encoded by 11 exons. Exon 2, 3 and 10 are alternative spliced, allowing six combinations (2-3-10-; 2+3-10-; 2+3+10-; 2-3-10+; 2+3-10+; 2+3+10+). Thus, in the human brain, the tau proteins constitute a family of six isoforms with the range from 352-441 amino acids. They differ in either no, one or two inserts of 29 amino acids at the N-terminal part (exon 2 and 3), and three or four repeat-regions at the C-terminal part exon 10 missing. So, the longest isoform in the CNS has four repeats (R1, R2, R3 and R4) and two inserts (441 amino acids total), while the shortest isoform has three repeats (R1, R3 and R4) and no insert (352 amino acids total). All of the six tau isoforms are present in an often hyperphosphorylated state in paired helical filaments from Alzheimer's Disease brain. In other neurodegenerative diseases, the deposition of aggregates enriched in certain tau isoforms has been reported. When misfolded this otherwise very soluble protein can form extremely insoluble aggregates that contribute to a number of neurodegenerative diseases.

Supplier: Brady Worldwide

Indoor/outdoor safety signs from Brady® are available in a variety of materials, allowing users to choose the material and size that best fits any application.

Supplier: Novus Biologicals

The Apolipoprotein A-I / ApoA1 Antibody (1E12) [Biotin] from Novus Biologicals is a mouse monoclonal antibody to Apolipoprotein A-I / ApoA1. This antibody reacts with human. The Apolipoprotein A-I / ApoA1 Antibody (1E12) [Biotin] has been validated for the following applications: Western Blot, ELISA.

Supplier: Proteintech

The ARNTL antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ARNTL. This antibody recognizes human,mouse,rat antigen. The ARNTL antibody has been validated for the following applications: ELISA, IP, WB analysis.

Supplier: Brady Worldwide

Indoor/outdoor safety signs from Brady® are available in a variety of materials, allowing users to choose the material and size that best fits any application.

Supplier: TCI America

CAS Number: 501-53-1
MDL Number: MFCD00000640
Molecular Formula: C8H7ClO2
Molecular Weight: 170.59
Purity/Analysis Method: >96.0% (T)
Form: Clear Liquid
Boiling point (°C): 103
Melting point (°C): 0
Flash Point (°C): 80
Specific Gravity (20/20): 1.21
Storage Temperature: 0-10°C

Supplier: MilliporeSigma

The HisTag® Antibody HRP Conjugate kit contains a horseradish peroxidase-conjugated HisTag® Monoclonal Antibody that is useful as a single detection reagent, thus eliminating cross-reactivity associated with secondary antibody reagents

Supplier: TCI America

CAS Number: 383-62-0
MDL Number: MFCD00013662
Molecular Formula: C4H5ClF2O2
Molecular Weight: 158.53
Purity/Analysis Method: >97.0% (GC)
Form: Clear Liquid
Boiling point (°C): 96
Flash Point (°C): 20
Specific Gravity (20/20): 1.27

Supplier: TCI America

CAS Number: 40615-39-2
MDL Number: MFCD00010113
Molecular Formula: C31H32N2O7
Molecular Weight: 544.60
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 151
Specific rotation [a]20/D: 7 deg (C=1, MeOH)
Storage Temperature: 0-10°C

Supplier: TCI America

(stabilized with MEHQ)
CAS Number: 2867-47-2
MDL Number: MFCD00008589
Molecular Formula: C8H15NO2
Molecular Weight: 157.21
Purity/Analysis Method: >98.5% (GC)
Form: Clear Liquid
Boiling point (°C): 70
Melting point (°C): -30
Flash Point (°C): 57
Specific Gravity (20/20): 0.93

Supplier: Brady Worldwide

Indoor/outdoor safety signs from Brady® are available in a variety of materials, allowing users to choose the material and size that best fits any application.

Supplier: Brady Worldwide

Indoor/outdoor safety signs from Brady® are available in a variety of materials, allowing users to choose the material and size that best fits any application.

Supplier: Novus Biologicals

The ASAH1 Antibody (2C9) from Novus Biologicals is a mouse monoclonal antibody to ASAH1. This antibody reacts with human. The ASAH1 Antibody (2C9) has been validated for the following applications: Western Blot, ELISA, Immunohistochemistry-Paraffin.

Supplier: Brady Worldwide

Indoor/outdoor safety signs from Brady® are available in a variety of materials, allowing users to choose the material and size that best fits any application.

Supplier: Brady Worldwide

Indoor/outdoor safety signs from Brady® are available in a variety of materials, allowing users to choose the material and size that best fits any application.

Supplier: TCI America

CAS Number: 4083-64-1
MDL Number: MFCD00002030
Molecular Formula: C8H7NO3S
Molecular Weight: 197.21
Purity/Analysis Method: >95.0% (T)
Form: Clear Liquid
Color: Colorless
Boiling point (°C): 130
Melting point (°C): -2
Flash Point (°C): 145
Specific Gravity (20/20): 1.30

Supplier: Proteintech

The HLA-DPB1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HLA-DPB1. This antibody recognizes human antigen. The HLA-DPB1 antibody has been validated for the following applications: ELISA, IHC analysis.

Supplier: Prosci

CTSA encodes a glycoprotein which associates with lysosomal enzymes beta-galactosidase and neuraminidase to form a complex of high molecular weight multimers. The formation of this complex provides a protective role for stability and activity. Deficiencies in this gene are linked to multiple forms of galactosialidosis.

Supplier: Lifeline Cell Technology

VascuLife® EnGS-Mv is optimized for the culture of human microvascular endothelial cells, and supports the rapid proliferation of these cells in a 5% serum environment.

Supplier: TCI America

CAS Number: 372-31-6
MDL Number: MFCD00000424
Molecular Formula: C6H7F3O3
Molecular Weight: 184.11
Purity/Analysis Method: >98.0% (GC)
Form: Clear Liquid
Color: Colorless
Boiling point (°C): 132
Flash Point (°C): 39
Specific Gravity (20/20): 1.25