24154 Results for: "14-Heptacosanone"

Supplier: Prosci

TNFRSF14 Antibody: Tumor necrosis factor receptor (TNFR) superfamily members are defined by cysteine-rich domains in their extracellular regions that bind TNF-related ligands that share a common structural homology in their extracellular domain. TNFRSF14 was initially identified as the Herpesvirus entry mediator and upon binding to the herpes simplex virus (HSV) envelope glycoprotein D or either of its natural ligands LIGHT and lymphotoxin alpha (LT), activates the transcription factors NF-kappa B and AP-1. Activation of this signal transduction pathway in T cells stimulates T cell proliferation and cytokine production, leading to inflammation and enhanced CTL-mediated tumor immunity, suggesting that these proteins may be useful as potential targets for controlling cellular immune responses.

Supplier: Prosci

C-Type Lectin Domain Family 10 Member A (CLEC10A) is a type II transmembrane C-type lectin that is expressed on immature myleloid dendritic cells and alternatively activated (tolerogenic) macrophages. CLEC10A/MGL binds and internalizes molecules with terminal nonsialylated GalNAc carbohydrates such as the Tn carcinoma antigen. CLEC10A/MGL also binds the GP envelope glycoprotein on Marburg and Ebola viruses and enhances viral entry and infectivity. It constitute a unique class of C-type lectins because of their specificity for galactose and its structural homologues. CLEC10A is thought to participate in the recognition of molecules from both altered self and pathogens due to its monosaccharide specificity for Gal and N-acetylgalactosamine (GalNAc). Human and rat carry a single gene for CLEC10A/MGL, while mouse has two closely related MGL1 and MGL2 genes.

Supplier: Biosensis

P75NTR Monoclonal antibody, Clone: MC192, Host: mouse, Reactivity: rat, Isotype: IgG1, Conjugate: ATTO 488, Immunogen:N-octyl glucoside solubilized proteins from isolated PC12 cell plasma membranes, Synonyms: NGF r

Supplier: Freudenberg Medical

HelixMark® peristaltic pump platinum-cured silicone tubing is designed and manufactured for use with peristaltic pumps and other applications with higher effective forces. Peristaltic pump tubing undergoes a Special Stabilization Process (SSP), providing the additional benefits of superior strength, performance, and longer life. Tubing offers proven long wear and volumetric consistency over 8-,12- and 24-hour process runs.

Supplier: Bioss

The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein shares a similar domain structure with CARD11 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. Two alternatively spliced variants of this gene encoding distinct isoforms have been reported.

Supplier: MP Biomedicals

Hemin is an iron-containing porphyrin.It is a Protoporphyrin IX containing a ferric iron ion (Heme B) with a chloride ligand.

Supplier: Prosci

TNFRSF14 Antibody: Tumor necrosis factor receptor (TNFR) superfamily members are defined by cysteine-rich domains in their extracellular regions that bind TNF-related ligands that share a common structural homology in their extracellular domain. TNFRSF14 was initially identified as the Herpesvirus entry mediator and upon binding to the herpes simplex virus (HSV) envelope glycoprotein D or either of its natural ligands LIGHT and lymphotoxin alpha (LT), activates the transcription factors NF-kappa B and AP-1. Activation of this signal transduction pathway in T cells stimulates T cell proliferation and cytokine production, leading to inflammation and enhanced CTL-mediated tumor immunity, suggesting that these proteins may be useful as potential targets for controlling cellular immune responses.

Supplier: SW Safety Solutions

Engineered for life science environments, these durable gloves provide protection from chemicals without sacrificing the grip or dexterity needed to handle fine work details with full confidence.

Supplier: Vileda Professional - FHP

SpillEx Pads are the ideal solution for spill pickup or equipment leaking, makes free from the risk of cross contamination.

Supplier: AVIDITY SCIENCE

Two-In-One system provides DI water to a storage tank and ultrapure water through dispensing gun.

Supplier: AVIDITY SCIENCE

Puro™ III T and Geno™ II T are small in size; big on benefits. Providing RO or DI lab water to startup facilities.

Supplier: Sartorius

These Cubis® II premium high capacity laboratory balances are ideal for high-performance portfolio of both labs weighing hardware and software.

Supplier: Mettler Toledo

The XPR26PC allows fast and highly accurate pipette verifications according to ISO8655 for volumes between 1 and 100 µl. Supported by status light, level control, and internal calibration, producing reliable results every time.

Supplier: Rockland Immunochemical

YPEL4 (yippee-like 4) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL4 is ubiquitously expressed in adult tissues and has been shown to associate with the major vault protein (MVP). It has been suggested that MVP can inhibit YPEL4's ability to activate Elk-1 in the MAPK signaling pathway.

Supplier: Promega Corporation

Recombinant full-length human PDK1 was expressed by baculovirus in Sf9 insect cells using an N-terminal His tag. PDK1 (3-phosphoinositide-dependent protein kinase) is activated by the presence of PtdIns(3,4,5)P3 or PtdIns(3,4)P2.

Supplier: Prosci

NIK Antibody: Nuclear factor kappa B (NF-kappa B) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappa B mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNF alpha , LPS and mitogens. A serine/threonine protein kinase which mediates NF-kappa B activation by IL-1, TNF alpha and CD95 was identified recently and designated NIK (for NF-kappa B inducing kinase). NIK is an activator of I kappa B kinase alpha and beta (IKK alpha and IKK beta ). Therefore, NIK is a key molecule in the NF-kappa B signaling pathway leading to the induction of a variety of gene expression in response to proinflammatory cytokines and bacteria products.

Supplier: Prosci

NIK Antibody: Nuclear factor kappa B (NF-kappa B) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappa B mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFalpha , LPS and mitogens. A serine/threonine protein kinase which mediates NF-kappa B activation by IL-1, TNFalpha and CD95 was identified recently and designated NIK (for NF-kappa B inducing kinase). NIK is an activator of Ikappa B kinase alpha and beta (IKKalpha and IKKbeta ;). Therefore, NIK is a key molecule in the NF-kappa B signaling pathway leading to the induction of a variety of gene expression in response to proinflammatory cytokines and bacteria products.

Supplier: Bioss

The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein shares a similar domain structure with CARD11 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. Two alternatively spliced variants of this gene encoding distinct isoforms have been reported.

Supplier: VWR International

Digital orbital shakers are designed for a wide range of applications including solubility studies, extraction procedures, and cell cultures that require accurate and reproducible results.

Supplier: Promega Corporation

Recombinant full-length human CDK9 and CyclinK proteins were co-expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. CDK9/CyclinK is a member of the cyclin-dependent protein kinase (CDK) family.

Supplier: Prosci

TNFRSF14 Antibody: Tumor necrosis factor receptor (TNFR) superfamily members are defined by cysteine-rich domains in their extracellular regions that bind TNF-related ligands that share a common structural homology in their extracellular domain. TNFRSF14 was initially identified as the Herpesvirus entry mediator and upon binding to the herpes simplex virus (HSV) envelope glycoprotein D or either of its natural ligands LIGHT and lymphotoxin alpha (LT), activates the transcription factors NF-kappa B and AP-1. Activation of this signal transduction pathway in T cells stimulates T cell proliferation and cytokine production, leading to inflammation and enhanced CTL-mediated tumor immunity, suggesting that these proteins may be useful as potential targets for controlling cellular immune responses.

Supplier: Rockland Immunochemical

IFITM1 (Interferon inducible transmembrane protein 1) is a member of the IFN-inducible transmembrane protein family. It is an essential mediator of interferon-gamma-induced antiproliferation and plays a role in the control of cell growth. IFITM1 is upregulated in several tumor types and may be useful as a tumor biomarker. Both mouse IFITM1 and IFITM3 are expressed on the cell surfaces of primordial germ cells in a developmentally-regulated manner. IFITM1 activity is required for primordial germ cell transit, and IFITM1 acts as a repulsive molecule by repelling non-IFITM1-expressing primordial germ cells from the mesoderm into the endoderm.

Supplier: Upchurch Scientific

Upchurch Scientific® PEEK™ (polyetheretherketone) polymer tubing is biocompatible, chemically inert to most solvents, and can be used to replace stainless steel tubing in most liquid analytical systems.

Supplier: Prosci

Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. SLC25A14 has an N-terminal hydrophobic domain that is not present in other UCPs.

Supplier: YSI

YSI's EcoSense® product line of compact, handheld instruments includes the pH100A pH meter. For simple, one handed operation for pH readings or mV values and temperature the pH100A is a logical choice. Designed specifically for spot sampling applications, the pH100A meter will fill the need for simple, one-handed operation instrumentation.

Supplier: Cytiva

Sera-Mag Oligo(dT)-Coated Magnetic Particles enable convenient mRNA isolation and extraction. Sera-Mag Oligo(dT) Magnetic Particles bind target mRNA through pairing of the polyadenylated RNA tail found on the 3’ end of mRNA to the covalently bound oligo(dT) groups on the surface of the particles. This binding is easily accomplished using standard hybridisation conditions. Versatile and efficient methods for mRNA purification are critical, given that eukaryotic mRNA makes up only 1 to 3% of total cellular RNA. Sera-Mag Oligo(dT) Magnetic Particles remove 90% or more of mRNA from total RNA with just one extraction.

Supplier: MP Biomedicals

Storage: Store at room temperature (15-30 °C)
L-Tyrosine is one of the three aromatic amino acids, and is formed from the hydroxylation of phenylalanine.
L-Tyrosine is used in cell culture media and is a component of MEM amino acids solution. L-Tyrosine has been used in a cell culture study of the amino acid transport system b0,+ in epithelial cells isolated from chicken jejunum.

Supplier: Eagle Biosciences

Swine IFN Gamma EIA detect Swine Interferon Gamma concentrations in cell culture, serum, and plasma.

Supplier: Hamilton

The Hamilton PRP™-C18 HPLC column is designed to provide high-efficiency, reversed-phase separations over an extended column life in nearly any mobile phase or pH.

Supplier: Rockland Immunochemical

Tumor necrosis factor receptor (TNFR) superfamily members are defined by cysteine-rich domains in their extracellular regions that bind TNF-related ligands that share a common structural homology in their extracellular domain. TNFRSF14 was initially identified as the Herpesvirus entry mediator and upon binding to the herpes simplex virus (HSV) envelope glycoprotein D or either of its natural ligands LIGHT and lymphotoxin alpha (LT), activates the transcription factors NF-kB and AP-1. Activation of this signal transduction pathway in T cells stimulates T cell proliferation and cytokine production, leading to inflammation and enhanced CTL-mediated tumor immunity, suggesting that these proteins may be useful as potential targets for controlling cellular immune responses.