69502 Results for: "1-tert-Butyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine"

Supplier: Cytiva

Superdex prep grade is a preparative gel filtration medium with a composite matrix of dextran and agarose

Supplier: Allegro

Cooling products are designed to protect and provide comfort to workers who must function in environments with excessive heat.

Supplier: Rockland Immunochemical

KLRA2 (also known as Ly49B) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA2 is thought to be an inhibitory receptor and associates with the protein tyrosine phosphatases SHP1, SHP2, and SHIP in transfected cells. This antibody is predicted to not cross-react with other LY49 receptors.

Supplier: G-Biosciences

G-Biosciences' HOOK™ Cell Surface Protein Isolation kit uses our HOOK™ biotin labeling and purification technology in conjunction with our Mammalian Cell PE LB™ lysis buffer to conveniently label cell surface proteins and isolate them for further analysis, including Western blotting

Supplier: Advanced Biomatrix

Advanced BioMatrix products are recognized for purity, functionality, quality, and lot-to-lot consistency, allowing for reproducibility in research.

Supplier: VWR International

Look for the V at the neck.™ Economical, disposable tools for transferring, collecting, and handling chemical and biological materials.

Supplier: Advanced Biomatrix

Advanced BioMatrix products are recognized for purity, functionality, quality, and lot-to-lot consistency, allowing for reproducibility in research.

Supplier: Prosci

ABP1 is a membrane glycoprotein that is expressed in many epithelium-rich and/or hematopoietic tissues and oxidatively deaminates putrescine and histamine. The protein may play a role in controlling the level of histamine and/or putrescine in these tissues. It also binds to and is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels.This gene encodes a membrane glycoprotein that is expressed in many epithelium-rich and/or hematopoietic tissues and oxidatively deaminates putrescine and histamine. The protein may play a role in controlling the level of histamine and/or putrescine in these tissues. It also binds to and is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels.

Supplier: Prosci

NKG2D Ligand 2 (N2DL2) is a member of a family of cell-surface proteins. N2DL2 function as ligands for human cytomegalovirus glycoprotein UL16. N2DL2 is anchored to the membrane via a GPI-linkage. N2DL2 is bind to human NKG2D, an activating receptor expressed on NK cells, NKT cells, T cells. Engagement of NKG2D results in the activation of cytolytic activity and cytokine production by these effects cells. The ULBPs are expressed on some tumor cells and have been implicated in tumor surveillance.

Supplier: Eppendorf

Eppendorf ep Dualfilter T.I.P.S.® SealMax® Racks provide advanced self-sealing pipette tips in 'PCR clean and Sterile' grade, featuring unique two-phase filters for unparalleled protection against contamination in sensitive lab applications.

Supplier: Cytiva

Whatman chromatography papers are widely used across the world, reflecting their purity, high quality and consistency. They are made from specially selected cotton cellulose and rigorously quality controlled to ensure uniformity within the grade.

Supplier: Invitrogen

This luminol-based enhanced chemiluminescence (ECL) horseradish peroxidase (HRP) substrate for Western blotting provides very stable light output especially for documentation with CCD camera imagers with sensitivity in the mid-femto range.

Supplier: DRG International

An enzyme immunoassay for the quantitative determination of Intact-PTH (Parathyroid Hormone) in serum.

Supplier: Antyila Scientific

Reduce maintenance time with self-diagnostic function.

Supplier: Rockland Immunochemical

Anaplastic thyroid cancer is one of the most lethal forms of cancer, but the precise carcinogenic mechanism has not been identified. TMEM184C, also known as TMEM34, was identified in a cDNA microarray analysis as being down-regulated in anaplastic thyroid cancers compared to normal thyroid tissues. TMEM184C protein expression was also lower in cell lines derived from these types of cancers compared to that of normal thyroid tissues or cell lines based on other types of thyroid cancers. Furthermore, transfection of TMEM34 into KTA2 cells led to the inhibition of cell growth, suggesting that TMEM184C might act as a tumor suppressor in anaplastic thyroid cancers.

Supplier: Rockland Immunochemical

The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT5 localizes to mitochondria, deacetylates carbamoyl phosphate synthetase 1, and is involved in the regulation of the urea cycle.

Supplier: Rockland Immunochemical

The THAP domain-contining protein 11 (THAP11), also known as Ronin, is an essential factor involved in embryonic stem (ES) cell pluripotency and cell growth (1). THAP 11 contains a THAP domain, a conserved DNA-binding domain common to many proteins associated with chromatin modification and gene expression silencing, and has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases (2). THAP11 can also negatively regulate CD44 v6 expression through its interaction with the poly(rC) binding protein PCBP1 (3).

Supplier: Rockland Immunochemical

The calcium channel protein CACNA1H is a T-type member of the alpha-1 subunit family that is part of the voltage-dependent calcium channel complex which mediates the influx of calcium ions into the cell upon membrane polarization (1,2). CACNA1H is a subunit of Cav3.2 T-type calcium channel that is involved in neurological disorders such as epilepsy and pain (2,3). CACNA1H associates with the caveolin protein Cav-3 and it is thought that Cav-3 regulates the Protein Kinase A (PKA) modulation of CACNA1H-containing Cav3.2 T-type calcium channels (4).

Supplier: Rockland Immunochemical

LSD1 (lysine specific demethylase 1) is a component of the histone demethylase complex that uses FAD as a prosthetic goup. LSD1 may have a dual effect on gene transcription. As it demethylates the mono- and dimethylated ‘Lys-4’ of histone H3, which are associated with transcriptional activation, LSD1 can act as a repressor of gene expression. However, LSD1 is also capable of demethylating ‘Lys-9’ of histone H3, a specific tag for epigenetic transcriptional repression, thereby leading to activation of androgen receptor target genes. LSD1 therefore is ideal for research in different processes such as Stem and Cancer Cell Biology, Embryonic Development, Epigenetics and Cell Differentiation and Proliferation.

Supplier: Ansell Healthcare

High-performance Endurosaf™ aprons feature a strong and durable 8-9 millimeter die-cut Enduro 2000™ polyurethane material that rivals traditional materials such as neoprene, nitrile, vinyl and other films.

Supplier: NANOENTEK USA INC.

ADAM™ CellT is an automated cell counter that complies with the 21 CFR Part 11 which is a regulation on electronic records and signatures for use in cGMP facilities. Data cannot be modified by any user. Every action of users is recorded in an audit trail which includes the date, time, and specific details of the action.

Supplier: Elma

The dependable, state-of-the-art 37 kHz Elmasonic E Plus series includes 9 tank sizes with simple, user-friendly operation. Samples are rapidly mixed, dispersed, dissolved, or homogenized in Dynamic mode, while Eco mode offers quiet gentle cleaning at reduced power.

Supplier: Rockland Immunochemical

The NIPSNAP proteins comprise a family of evolutionarily well-conserved proteins with strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. NIPSNAP2, a novel gene encoding a protein with tyrosine phosphorylation sites and a transmembrane domain, is co-amplified with EGFR in approximately 40% of glioblastomas, the most common and malignant form of central nervous system tumors. It is widely expressed and most abundant in heart and skeletal muscle. NIPSNAP proteins have been suggested to be important in vesicular transport. NIPSNAP2 antibody is predicted to not cross-react with any other members of the NIPSNAP protein family.

Supplier: Contec

Low Endotoxin Irradiated Alcohol contains 70% by volume USP grade isopropanol (IPA), and 30% water for injection (WFI). The alcohol blend is 0.2 micron filtered, filled, and bagged in an Grade C or ISO Class 7 cleanroom. The alcohol blend is certified to have an endotoxin level <0.25 EU/ml, making it suitable for product contact surfaces. The bottles are provided with the triggers installed and gamma irradiated at no less than 25 kGy. Each lot is sterility tested and certified.

Supplier: Ansell Healthcare

High-performance Endurosaf™ aprons feature a strong and durable 8-9 millimeter die-cut Enduro 2000™ polyurethane material that rivals traditional materials such as neoprene, nitrile, vinyl and other films.

Supplier: Antibodies.com

Human IL37 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human IL37 in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Antibodies.com

Human EZH2 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human EZH2 in serum, plasma, tissue homogenates, and other biological fluids.

Supplier: Tosoh Bioscience

These silica- and polymer-based columns are ideal for reversed-phase applications such as pharmaceutical drugs, forensic compounds, derivatised amino acids, carbohydrates, steroids, lipids and fatty acids. Depending on their molecular weight, peptides may be analysed with the 80 to 140 Å silica-based columns, while proteins require a larger pore size column (200 to 300 Å).

Supplier: Enzo Life Sciences

Cyto-ID® Green long-term cell tracer kit is suitable for a variety of applications including long term cell viability, cytotoxicity, cell adhesion, cell migration and cell-cell fusion studies.

Supplier: Enzo Life Sciences

Cyto-ID® Red long-term cell tracer kit is suitable for a variety of applications including long term cell viability, cytotoxicity, cell adhesion, cell migration and cell-cell fusion studies.