103467 results for "1-Hydroxy-3-methyl-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one&amp"

The Therapak® range of insulated shippers features five popular cooler sizes that are inventoried at two locations in the United States in order to provide a maximum three day ground or truck shipment turnaround to any point in the Continental U.S. The two facility approach offers freight economies to Eastern, Central, and Western region shipping points. Warehouses are located in Buford, Georgia and Claremont, California.

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FreeZone® Triad® Benchtop Freeze Dryers, Labconco®

Supplier: Labconco

FreeZone® Triad® Benchtop Freeze Dryers are designed for multiple types of lyophilization: flask, bulk and stoppering vials. With the ability to freeze dry samples in so many different forms, the Triad’s versatility and compact design make it perfect for busy labs. Now with Lyo-Works™ OS the Triad is smarter than ever, making freeze drying even challenging samples easy.

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Celestron StarSense Explorer DX 130AZ

Supplier: Celestron International

StarSense Explorer is ideal for beginners thanks to the app’s user-friendly interface and detailed tutorials.

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Human Proinsulin C-peptide (55-89)

Supplier: Anaspec

Proinsulin C-peptide is the sequence of C peptide as it exists within proinsulin, the precursor to insulin which consists of insulin A chain, insulin B chain and C peptide (connecting peptide). In proinsulin, C peptide provides a means to ensure correct folding and assembly of the A and B chains. It is eventually cleaved away by proteases PC2, PC1/3 and CPE, at the flanking Arg-Arg and Lys-Arg basic residues (Arg-Arg-C peptide-Lys-Arg). Although C peptide is not present in mature insulin, it is stored in secretory granules, and eventually released into the bloodstream together with insulin in nearly equimolar amounts. Whereas insulin is metabolized quickly from circulation, C-peptide exhibits a slow turnover rate (>30 minutes). The measurement of the C-peptide is an important test for the β-cell function. In the red blood cells of type 2 diabetic patients, Na+,K+, ATPase activity is strongly related to blood C-peptide levels. C-peptide signal transduction in human renal tubular cells involves the activation of phospholipase C and PKC-δ and PKC-varepsilon, as well as RhoA, followed by phosphorylation of ERK1/2 and JNK and a parallel activation of Akt. C-peptide shows specific binding to a G-protein-coupled membrane binding site, resulting in Ca2+ influx, activation of mitogen-activated protein kinase signalling pathways and stimulation of Na+, K+ ATPase and endothelial nitric oxide synthase.
Sequence: RREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKR
MW: 3617 Da
% Peak area by HPLC: 95
Storage condition: -20° C

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pNL2.3[secNluc/Hygro] Vector, 20 µg, Promega

Supplier: Promega Corporation

The pNL1.3[secNluc], pNL3.3[secNluc/minP], pNL2.3[secNluc/Hygro] and pNL1.3.CMV[secNluc/CMV] Vectors offer a secreted small luciferase reporter in various promoter-driven or promoterless configurations for expression in mammalian cells.

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pGL4.32[luc2P/NF-kappa-B-RE/Hygro] Vector, 20 µg, Promega

Supplier: Promega Corporation

pGL4.44[luc2P/AP1 RE/Hygro], pGL4.49[luc2P/TCF-LEF RE/Hygro], pGL4.29[luc2P/CRE/Hygro], pGL4.30[luc2P/NFAT-RE/Hygro], pGL4.32[luc2P/NF-κB-RE/Hygro], pGL4.33[luc2P/SRE/Hygro] and pGL4.34[luc2P/SRF-RE/Hygro] Vectors can explore various signaling pathways.

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Anti-INCENP Rabbit Polyclonal Antibody

Supplier: Genetex

Chromosomal passenger proteins are members of a group of proteins that move from centromeres to the spindle midzone during mitosis. INCENP (Inner Centromere Protein) is a chromosomal passenger protein with an essential role in mitosis and meiosis. It is a complex highly basic multidomain protein that is dynamically translocated from metaphase chromosomes to the spindle midzone during or just prior to anaphase. Some INCENP transfers to the equatorial cortex before formation of the cleavage furrow. Ultimately, it is discarded in the midbody at the completion of cytokinesis. INCENP, in complex with the passenger proteins aurora B kinase and survivin, acts at multiple points during mitosis. Studies in knockout mice established INCENP as essential for mouse development and viability. Loss of INCENP results in chromosome segregation defects and failures in cytokinesis. Targeting of survivin to its centromeric and central spindle locations during mitosis is dependent on INCENP. Direct binding of INCENP to beta tubulin has been demonstrated. Interactions of INCENP with heterochromatin protein HP1Hsa alpha and histone H2A.Z were also reported. INCENP levels are increased in several human cancer lines.