271 Results for: "1-(Methylamino)acetone hydrochloride"

CAS: 506-59-2; EC No: 208-046-5; MDL No: MFCD00012477; RTECS: IQ0220000 Crystalline; Linear Formula: (CH3)2NH·HCl; Molecular Formula: C2H7N·HCl; MW: 81.54 Melting Point: 170-173° Hygroscopic

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alpha1-Adrenergic receptor (alpha-AR) antagonist. Prototypical calcium channel protein inhibitor that blocks the L-type Ca2+ channels in smooth and cardiac muscle cells. Vasodilator known to reduce the renal clearance of digoxin and used to control hypertension, angina, cardiac arrhythmia and vascular headaches. Apoptosis inducer in primary and metastatic colon adenocarcinoma human cell lines in vitro. Inhibitor of drug efflux pump proteins such as Mdr (P-glycoprotein) which are often over-expressed in certain tumor cell lines. Substrate of CYP3A4 and CYP2C6. Used in fluorescent cell sorting for DNA content, as it blocks efflux of a variety of DNA-binding fluorophores such as Hoechst 33342. Anti-diabetic in animal models by limiting TXNIP expression.

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Verapamil Hydrochloride

Supplier: Adipogen

Verapamil hydrochloride is an alpha-adrenergic receptor (alpha-AR) antagonist and calcium channel protein inhibitor that blocks the L-type Ca2+ channels in smooth and cardiac muscle cells. Verapamil is an antiarrhythmic agent and vasodilator known to reduce the renal clearance of digoxin and induce apoptosis in primary and metastatic colon adenocarcinoma human cell lines in vitro. It has been observed that verapamil can induce currents by itself, presumably by acting on the potassium and chloride leakage. Verapamil has also been used as an inhibitor of drug efflux pump proteins such as Mdr (P-glycoprotein). Verapamil is a substrate of CYP3A4 and CYP2C6. It is also used in fluorescent cell sorting for DNA content, as it blocks efflux of a variety of DNA-binding fluorophores such as Hoechst 33342. Recent research has shown verapamil to be an effective treatment for diabetes in animal models. Verapamil helps treat diabetes by limiting TXNIP expression.

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Triethanolamine hydrochloride ≥99%, Powder

Supplier: MP Biomedicals

Triethanolamine is a zwitterionic buffer.

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1,1-Dimethylbiguanide hydrochloride 98%, white crystalline powder

Supplier: MP Biomedicals

1,1-Dimethylbiguanide hydrochloride is suitable biguanide agent used in a study to investigate its role in enhancing the secretions of plasma active glucagon-like peptide-1 (GLP-1) levels.

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Pyridoxine hydrochloride ≥98%, white powder

Supplier: MP Biomedicals

Pyridoxine Hydrochloride is one of the vitamins of the B6 complex; present in many foodstuffs (yeast, liver and cereals).

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Smoothened agonist dihydrochloride hydrate ≥98% (by HPLC), water soluble

Supplier: Adipogen

Cell permeable Sonic hedgehog (Shh) agonist. Cell permeable smoothened (Smo) agonist. Induces Sonic hedgehog (Shh) pathway activation and counteracts cyclopamine inhibition of Smo. Acts as an activator of Smo at low concentrations and as an inhibitor of Smo at very high concentrations. Potent activator of VEGF expression in vitro.

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(S,E)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(2,3-dimethylguanidino)pentanoic acid

Supplier: Bachem Americas

Sequence: Fmoc-Arg(Me)₂-OH (symmetrical)

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Chlortetracycline hydrochloride, 900 u/mg, yellow powder

Supplier: MP Biomedicals

Chlortetracycline hydrochloride has antimicrobial action similar to tetracycline hydrochloride, but it is somewhat less active against many Gram-negative organisms. It was first isolated from the culture of Streptomyces aureofacien.

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Bupivacaine hydrochloride

Supplier: MP Biomedicals

Bupivacaine is a sodium channel blocker, local anesthetic. It binds to the intracellular portion of sodium channels and blocks sodium influx into nerve cells, which prevents depolarization. Since pain transmitting nerve fibres tend to be thinner and either unmyelinated or lightly myelinated, the agent can diffuse more readily into them than into thicker and more heavily myelinated nerve fibres like touch, proprioception, etc. (Myelin is non-polar / lipophilic). It should be noted, however, that bupivacaine also blocks specific potassium channels, an effect contributing to resting membrane potential depolarization.

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2,3,5-Triphenyltetrazolium chloride (TTC) ≥99%

Supplier: Adipogen

Triphenyl tetrazolium chloride, TTC, or simply tetrazolium chloride is a redox indicator commonly used in biochemical experiments especially to indicate cellular respiration.

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Triethanolamine (trolamine) ≥97%, liquid

Supplier: MP Biomedicals

Protein purification reagent Triethanolamine acts as an organic additive in the grinding of cement clinker and as a complexing agent for aluminum ions in aqueous solutions.
It is used as an emulsifier and a surfactant. It finds application in common products like dishwashing liquids, general cleaners, hand cleaners, shaving cream, metalworking fluids, liquid laundry detergents, paints and printing inks. It is used for the neutralization of fatty acids and adjusting buffer pH as well as utilized to dissolve oils. It acts as an effective complexing agent in electroless plating. Further, it is used in hair care products like hair dyes and wave sets.

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2,3,5-Triphenyltetrazolium chloride (TTC), white powder

Supplier: MP Biomedicals

2,3,5-Triphenyltetrazolium Chloride is a redox indicator. In the TTC assay (also known as TTC test or tetrazolium test), TTC is used to differentiate between metabolically active and inactive tissues. The white compound is enzymatically reduced to red TPF (1,3,5-triphenylformazan) in living tissues due to the activity of various dehydrogenases (enzymes important in oxidation of organic compounds and thus cellular metabolism), while it remains as white TTC in areas of necrosis since these enzymes have been either denatured or degraded.
2,3,5-Triphenyltetrazolium Chloride is commonly used in biochemical experiments especially to indicate cellular respiration. TTC has been employed in autopsy pathology to assist identification of post-mortem myocardial infarctions. Healthy viable heart muscle will stain deep red from the cardiac lactate dehydrogenase; while areas of potential infarctions will be more pale. Useful indicator for reducing substances