18187 Results for: "1-(3,6-Dibromo-2-fluorophenyl)-2-fluoroethanone"

Supplier: Prosci

Podoplanin is a type-1 transmembrane protein that belongs to Podoplanin family. PDPN expressed in various specialized cell types throughout the body. It highly expressed in placenta, lung, skeletal muscle and brain, weakly expressed in brain, kidney and liver. In placenta, PDPN expressed on the apical plasma membrane of endothelium, in lung, expressed in alveolar epithelium. PDPN physiological function is related to its mucin-type character. PDPN may be involved in cell migration and/or actin cytoskeleton organization. When expressed in keratinocytes, induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protrusions, and major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion. It requires for normal lung cell proliferation and alveolus formation at birth and Induces platelet aggregation. Nevertheless, it doesn’t have any effect on amino acid transport and the aquaporin-type water channels.

Supplier: VWR International

Digital orbital shakers are designed for a wide range of applications such as solubility studies, extraction procedures, and cell cultures that require accurate and reproducible results.

Supplier: National Public Seating

NPS wood frame science table is an asset to any lab or classroom. The 24×72" phenolic top can withstand various chemicals. Rubber footing and adjustable glides protect floors and allow for accurate leveling. Book compartments are an added feature for storage.

Supplier: Bioss

Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.Involvement in disease:Defects in SHOC2 are the cause of Noonan syndrome-like with loose anagen hair (NSLAH) . NSLAH children display macrocephaly, high forehead, hypertelorism, palpebral ptosis, low-set and posteriorly rotated ears, short and webbed neck and pectus anomalies. Affected subjects also have easily pluckable, sparse, thin and slow-growing hair.

Supplier: NEWPATH LEARNING LLC

Improve student test scores and involve parents in the process. Fun, exciting, interactive, and inclusive, these sets of content-based games help students master curriculum outlined in the current NSES Standards for grades 1-8. Written by teachers using research-based principles, each game has been tested and proven effective in classrooms like yours. Each Class Pack set of games provides comprehensive coverage of topics required for science testing at that grade level. Engage students in learning with over 750 review cards, each set focused on a specific topic, and an additional 12 double-sided game boards for study and review.

Supplier: Binder

The KBF-S ECO climatic chambers are very energy-efficient thanks to thermoelectric cooling technology with heat dissipation. The thermoelectric cooling technology means the KBF-S ECO series is also very quiet during operation.

Supplier: BTNX INC.

The Rapid Response™ Xylazine Test Strip (Liquid / Powder) detects the presence xylazine in liquid or powder samples at a cut-off concentration of 1000 ng/mL or higher.

Supplier: Rockland Immunochemical

Siglecs are vertebrate cell-surface lectins that recognize sialylated glycans and are involved in many physiological processes, such as glycoprotein turnover, cellular trafficking, and pathogen recognition. Most Siglecs are expressed on cells of the immune system. SIGLEC15 is a type-I transmembrane protein consisting of two immunoglobulin (Ig)-like domains, a transmembrane domain containing a lysine residue, and a short cytoplasmic tail. SIGLEC15 can interact with the activating adaptor molecules DAP12/10. Its activating signaling potential and unique preference for glycan recognition implies that SIGLEC15 may be involved in the immune surveillance of tumors and probably plays a conserved, regulatory role in the immune system of vertebrates.

Supplier: VWR International

Optimize projects with the Mega Star 1.6 general purpose centrifuge series. These versatile compact benchtop centrifuges provide maximum sample security and reproducibility in an intuitive, easy to use platform. Choose between a ventilated or refrigerated compact benchtop 1.6 L model, sold as an individual centrifuge or a package, to enhance productivity.

Supplier: Rockland Immunochemical

The Rhomboid family of proteins is made up of several widely conserved polytopic membrane serine proteases that play roles in growth and development. RHBDD1 is highly expressed in the testis and is involved in the cleavage of BIK, a proapoptotic member of the Bcl-2 family. Overexpression or suppression by RNAi of RHBDD1 in 293 cells will reduce or enhance BIK-mediated apoptosis, respectively, demonstrating that RHBDD1 modulates BIK-mediated apoptotic activity. In GC-1 cells, a spermatogonia cell line that can differentiate into spermatids within the seminiferous tubules, suppression of RHBDD1 expression by RNAi caused the cells to lose the ability to survive and differentiate in mouse seminiferous tubules, suggesting that RHBDD1 may be associated with mammalian spermatogenesis.

Supplier: Gold Standard Diagnostics

The AIX1000™ is the first FDA cleared, fully automated system for nontreponemal RPR syphilis testing

Supplier: Eppendorf

The Eppendorf CryoCube F740hi ULT freezer with the VisioNize touch-enabled screen allows for temperature monitoring and data export for documentation, controlled access to samples for greater security, and remote monitoring capabilities. Traditionally foamed polyurethane insulation enforced by vacuum insulation panels in freezer body and door ('i' versions) provides efficient insulation protection.

Supplier: Bioss

Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators.

Supplier: BLICKMAN INDUSTRIES

Freestanding cabinets are constructed with quality 304 stainless steel, #4 polish and have a seamless welded face preventing dirt collection while providing long lasting durability through unparalleled strength and corrosion resistance.

Supplier: Eppendorf

The Eppendorf CryoCube F740 series was developed to protect your samples and minimize running costs. The integration of the PhysioCare Concept® means that the CryoCube F740 is easier and more comfortable to use, supports an ergonomic workspace, and enables an optimal workflow in the laboratory. Traditionally foamed polyurethane insulation enforced by vacuum insulation panels in freezer body provides efficient insulation protection.

Supplier: BTNX INC.

The Rapid Response™ Nitazene Test Strip (liquid/powder) detects the presence nitazene in liquid or powder samples at a cut-off concentration of 2000 ng/ml or higher.

Supplier: Prosci

Members of the F-box protein family, such as FBXO36, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.Members of the F-box protein family, such as FBXO36, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).

Supplier: Labconco

Logic Class II, Type A2 Biosafety Cabinets (BSCs) offer comprehensive personnel, product and environmental protection from hazardous particulates, including risk group agents requiring BSL 1 to 4 containment. These cabinets are ideal for applications involving biological hazards, genetic material, antineoplastic drugs and other hazardous airborne particulates. All models ensure the highest standard of safety and performance.

Supplier: Cayman Chemical Company

A sensitive detection method for measuring both the free acid and ethyl amide forms of 17-phenyl trinor PGF_2α.

Supplier: Labconco

These stations provide user protection by keeping powders and particulates contained during weighing procedures

Supplier: Labconco

Logic Cart fits under any telescoping base stand. Features three small and one large compartments, one drawer, front panel cut out for dispensing wipers or gloves, and HDPE worksurface. W×D×H: 635×483×686 mm (25×19×27").

Supplier: New Pig

Provide a no-slip path in hazardous walking areas with this super-safe, adhesive-backed absorbent runner — its hi-viz yellow safety edges can't be missed.

Supplier: New Pig

Hassling with rubber-backed floor mats or rental mats? Make the switch to the mat that sticks — our super-safe, adhesive-backed commercial absorbent runner. Perfect for grocery and retail environments. 

Supplier: Antyila Scientific

Advanced split beam optics ensure excellent accuracy and reproducibility.

Supplier: BTNX INC.

The Rapid Response™ Xylazine Test Strip Kit (Liquid / Powder) detects the presence xylazine in liquid or powder samples at a cut-off concentration of 1000 ng/mL or higher.

Supplier: MP Biomedicals

2,2-Azino-bis-(3-ethyl-benzthiazoline-6-sulfonic acid) (ABTS) has been used as a chromogenic substrate for horseradish peroxidase (HRP), both in general activity assays and in ELISA applications. Activity of HRP using ABTS appears about four-fold higher than using pyrogallol. It is mainly used as a substrate in sensitive peroxidase assays.
2,2′-Azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) is a peroxidase substrate suitable for use in ELISA procedures. This substrate produces a soluble end product that is green in color and can be read spectrophotometrically at 405 nm. The reaction may be stopped with 1% sodium dodecyl sulfate (SDS). Recommended for ELISA (microwell) procedures, not recommended for membrane applications.

Supplier: Germaine Laboratories

COVID-19/Flu A and B Ag combo rapid test cassette (swab) is a lateral flow immunochromatographic assay intended for the qualitative detection and differentiation of influenza A and influenza B nucleoprotein antigens, and SARS-CoV-2 nucleocapsid antigen.

Supplier: Germaine Laboratories

COVID-19/Flu A and B antigen combo rapid test cassette (Swab) is CLIA waived under FDA EUA, and provides faster diagnosis for improved patient care and cost-effectiveness. Results are available in 15 minutes.

Supplier: Labconco

Self-contained ductless enclosures allow safe handling of organic, formaldehyde, acid gas, sulfur compounds, or ammonia chemical fumes and vapors.

Supplier: Lauda-Brinkmann

Clear-view circulators with an insulating glass window and compact housing are suitable for direct observation of samples and viscosity measurements