58694 Results for: "(4R,5S)-2-(6-Benzhydrylpyridin-2-yl)-4,5-diphenyl-4,5-dihydrooxazole"

Supplier: Cayman Chemical Company

A cell-based assay for studying modulators of cellular glucose uptake.

Supplier: LGC Standards

TRC Vitamin B12

Supplier: Invitrogen

The Pierce™ Magnetic ChIP Kit provides a convenient method for efficient isolation of chromatin-bound DNA by immunoprecipitation for subsequent quantitation by PCR.

Supplier: Promega Corporation

The Wizard SV 96 Genomic DNA Purification System provides a high-throughput, membrane-based technique for preparation of genomic DNA from cultured cells and tissue, including mouse tails.

Supplier: LGC Standards

Organic Standard, Cyanocobalamin (Vitamin B12)

Supplier: LGC Standards

Organic Standard, Medroxyprogesterone-17-acetate

Supplier: Analytik Jena US

The blackPREP Rodent Tail DNA Kit has been specially optimized for isolating DNA from pieces of mouse and rat tails, guaranteeing extremely high yields in a very short period of time (typically 3 hours or less).

Supplier: LGC Standards

Organic Standard, Medroxyprogesterone-17-acetate 100 µg/mL in Acetonitrile

Supplier: Spectrum Chemicals

Aspartame, Powder, FCC is a well known sugar substitute and artificial sweetener that is widely used in food and drinks. It much sweeter than sucrose and leaves a longer lasting taste. Spectrum Chemical offers over 300 Food Grade (FCC) chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.

Supplier: Genetex

Chromatin, the physiological packaging structure of histone proteins and DNA, is considered a key element in regulating gene expression. Several complexes involved in transcriptional regulation function by either modifying histones or altering chromatin structure. Postranslational modifications of histones, such as acetylation, phosphorylation and methylation, contribute to the regulation of transcription. The ATP-dependent chromatin-remodeling complexes alter chromatin structure by using the energy of ATP hydrolysis to locally disrupt the association of histones with DNA, displacing the nucleosomes from promoter and enhancer regions, and therefore allowing transcription initiation. Chromatin remodeling complexes have been purified from a variety of organisms, and most cell types contain more than one type of complex. These complexes contain structurally related catalytic subunits, but differ in the way in which they manipulate chromatin. Three families of complexes have been described the SWI/SNF family, ISWI family, and Mi-2 family. The SWI/SNF family of ATP-dependent remodeling complexes was identified in yeast, drosophila, and human. It causes nucleosomes to change structure and/or position in order to allow transcriptional activators to gain access to their target sites. The SWI/SNF complex was originally identified in yeast as a 2 MDa complex, later shown to be highly conserved in all eukaryotes. Components of the hSWI/SNF complexes have been implicated in a range of cellular events including gene activation, regulation of cell growth, and development. The human homologue of yeast SNF5, SMARCB1, was identified in a two-hybrid screening performed to identify binding targets of the integrase of HIV, and the gene called INI1. Many studies have indicated that yeast SNF and its human counterparts are able to interact with sequence-specific transcription factors, which may recruit the complex to specific genes. For example, it has been shown that SMARCB1 interacts with the protooncogene c-Myc and the SWI complex is necessary for c-Myc mediated transactivation. Mutations in SNF5 and Brg1, both SWI components, suggest a connection of the complex with cancer. In fact, SMARCB1 displays properties of a tumor-suppressor gene, as sporadic rhabdoid tumors show biallelic loss-of-function mutations, and germline mutations confer and autosomal-dominant syndrome that predisposes patients to a variety of rhabdoid cancers.

Supplier: Anaspec Inc

This is a salt form of Aβ(1-42) known to form aggregates within a few days in water or recommended solvents. The salt form has been found to form fibrils, exerts cytotoxicity in neuronal models and so, used in studies that evaluate activity of agents that reverse amyloid-induced cytotoxicity.

Supplier: LGC Standards

TRC Acid Red 114 (Technical Grade)

Supplier: New England Biolabs (NEB)

Quickly and easily purify up to 100 µg of high quality total RNA from multiple sample types – all with one kit.

Supplier: LGC Standards

Organic Standard, Iron Pigment Yellow