58694 Results for: "(4R,5S)-2-(6-Benzhydrylpyridin-2-yl)-4,5-diphenyl-4,5-dihydrooxazole"

Supplier: INTACT GENOMICS, INC MS

Intact Genomics chemically competent Agrobacterium combo pack is perfect for scientists who require multiple Agrobacterium competent cell strains for their research. The chemically competent Agrobacterium combo pack contains three 50 µl aliquots of GV3101, AGL1, EHA105 and LBA4404 along with pCambia and our proprietary Agro Recovery Media.

Supplier: LGC Standards

Organic Standard, Betamethasone Acetate

Supplier: LGC Standards

TRC (±)-Warfarin Sodium

Supplier: ALADDIN SCIENTIFIC

Store under desiccating conditions. The product can be stored for up to 12 months.

Supplier: LGC Standards

rac-MDA (rac-3,4-Methylenedioxyamphetamine) 1.0 mg/ml in Methanol, LoGiCal, LGC Standards

Supplier: Eppendorf

Eppendorf epT.I.P.S.® 384 Reloads provide high-precision micropipette tips in 'Eppendorf Quality' and 'PCR clean' grades, tailored for 384-well plate applications, ensuring accuracy, reduced waste, and compatibility in high-throughput labs. The epT.I.P.S.® 384 pipette tips build a system together with the Research® plus and Xplorer® plus 16- and 24-channel pipettes, as well as 20 and 100 µl Move It® adjustable tip spacing pipettes for the utmost safety and reliability.

Supplier: Genetex

Lamins are type V intermediate filament proteins and are grouped into constitutively expressed B-type lamins and developmentally regulated A-type lamins. Lamin-binding proteins in the nuclear lamina and the nuclear interior include several protein families and/or types of proteins in higher eukaryotes such as the inner nuclear membrane proteins, lamin B receptor, emerin, and MANI, three isoforms of lamina-associated polypeptide 1 (LAP1), and several isoforms of LAP2. Up to six LAP 2 isoforms derive from a single gene by alternative splicing in mammals and various isoforms have been described in Xenopus. The best characterized LAP2 isoforms are the inner nuclear membrane protein LAP2 beta and the nucleoplasmic protein LAP2 alpha, which are identical in their N-terminal 187-amino acid constant region but differ in their C termini. While LAP2 beta binds to B-type lamins at the nuclear periphery and was suggested to regulate nuclear lamina growth , LAP2 alpha specifically interacts with A-type lamins within the nuclear interior as part of a detergent/salt-resistant nucleoskeletal structure.

Supplier: Rockland Immunochemical

The tumor necrosis factor (TNF) and TNF receptor (TNFR) gene superfamilies regulate numerous biological functions including cell proliferation, differentiation, and survival through regulating the activation of the transcription factor NF-kB and various mitogen-activated protein kinases. Nerve growth factor receptor (NGFR) was one of the earliest characterized members of this family. Also known as the low-affinity receptor p75NTR, this receptor is involved in several diverse functions such as apoptosis, neurite outgrowth during development, and myelination. Its ligands include NGF, brain-derived neurotrophic factor (BDNF), NT3, and NT4. NGFR can also associate with other NGF receptors such as Trk through the cytosolic and transmembrane domains and thus can function as a co-receptor that refines Trk affinity and specificity for neurotrophins. Finally, upon binding of various neurotrophins, NGFR associates with tumor necrosis factor receptor-6 (TRAF6), suggesting that it can potentially function as a signal transducer for NGF signals through NGFR.

Supplier: LGC Standards

Organic Standard, Tartrazine

Supplier: Rockland Immunochemical

Human Interleukin-13 AccuSignal ELISA Kit

Supplier: Electron Microscopy Sciences

The remarkably clear, non-distorted 3D image resolved by the GL Series optics is a result of advanced technologies in optical design. The GL Series Greenough design produces lifelike images in a large field of view and presents upright or erect images with astounding depth perception.

Supplier: Prosci

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA-Receptor (GABAA-R) subtype. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse. The GABAA-R is a multimeric subunit complex. To date six alphas, four betas and four gammas, plus alternative splicing variants of some of these subunits, have been identified. Injection in oocytes or mammalian cell lines of cRNA coding for alpha and beta subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a gamma subunit is required for benzodiazepine modulation. The various effects of the benzodiazepines in brain may also be mediated via different alpha subunits of the receptor. Lastly, phosphorylation of beta subunits of the receptor has been shown to modulate GABAA-R function.

Supplier: LGC Standards

Organic Standard, Limonene 1000 µg/mL in Isopropanol

Supplier: LGC Standards

Organic Standard, Sulfisomidine 100 µg/mL in Acetonitrile

Supplier: LGC Standards

Organic Standard, (16alpha)-21-Chloro-17-[(2-furanylcarbonyl)oxy]-16-methyl-pregna-1,4-diene-3,11,20-trione Mometasone

Supplier: LGC Standards

Organic Standard, Montelukast Sulfoxide (Mixture of Diastereomers)

Supplier: BeanTown Chemical

CAS: 63675-74-1; EC No: 264-408-2; MDL No: MFCD02083138 Solid; Molecular Formula: C16H14O2S; MW: 270.35 Melting Point: 191-197°

Supplier: LGC Standards

Trifluoperazine Hydrochloride 1.0 mg/ml in Methanol (as free base), LoGiCal, LGC Standards

Supplier: Bioss

CCDC19 is a 466 amino acid protein encoded by a gene mapping to human chromosome 1. Chromosome 1 is the largest human chromosome, spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1 and, considering the great number of genes, there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes Lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinson’s, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Supplier: Bioss

Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, encoded by this gene, which is a member of the phosphorylase b kinase regulatory subunit family. The gamma subunit also includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9B, also known as phosphorylase kinase deficiency of liver and muscle. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. Two pseudogenes have been found on chromosomes 14 and 20, respectively.[provided by RefSeq, Feb 2010].

Supplier: LGC Standards

TRC Desipramine Hydrochloride

Supplier: LGC Standards

Organic Standard, Basic Orange 2

Supplier: LGC Standards

TRC Sulfamethazine

Supplier: LGC Standards

TRC Megestrol Acetate

Supplier: LGC Standards

Organic Standard, Ciprofloxacin 100 µg/mL in Methanol

Supplier: MP Biomedicals

Storage: Room Temperature, desiccate, store under nitrogen.
Dimethyl Sulfoxide is a dipola, aprotic solvent. It has been shown to accelerate strand renaturation (1-10% concentration) and is believed to give the nucleic acid thermal stability against depurination.
Dimethyl Sulfoxide is used to enhance dermal absorption of many chemicals, as a solvent for many organic and inorganic compounds including fats, carbohydrates, dyes, resins, and polymers, in antifreeze or hydraulic fluids, as a cryopreservative for cell cultures, oxidation of thiols and disulfides to sulfonic acids, as a PCR cosolvent to help improve yields, especially in long PCR. DMSO is routinely used in polymerase chan reaction (PCR), amplification of cDNA libraries, DNA sequencing, column-loading buffers for poly (A)+ RNA selection, buffers for the transformation of competent E. coli, and transfection protocols.
To prepare sterile solutions use a teflon or nylon membrane to sterile-filter the DMSO - do not use a cellulose acetate membrane.

Supplier: Bioss

Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, encoded by this gene, which is a member of the phosphorylase b kinase regulatory subunit family. The gamma subunit also includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9B, also known as phosphorylase kinase deficiency of liver and muscle. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. Two pseudogenes have been found on chromosomes 14 and 20, respectively.[provided by RefSeq, Feb 2010].

Supplier: LGC Standards

Organic Standard, Geranyl acetate 100 µg/mL in Acetonitrile

Supplier: TCI America

CAS Number: 52431-78-4
MDL Number: MFCD00132898
Molecular Formula: C7H6N4OS
Molecular Weight: 194.21
Purity/Analysis Method: >90.0% (T)
Form: Crystal
Melting point (°C): 162

Supplier: Leica Microsystems

The Leica DM750 microscope is an advanced educational tool, with a wireless camera, Koehler illumination, and high-quality optics for clear observations. Enhance classroom experience with advanced imaging and comprehensive exploration.