PARK7
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Product Details & Documents
PARK7(DJ-1) control protein-HIS Epitope
- Control Protein
- PCA Assays
- ImmunoBlot
PARK7 or parkinson protein 7 belongs to the peptidase C56 family of proteins which acts as a positive regulator of androgen receptor-dependent transcription. PARK7 also functions as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. PARK7 mutations that impair transcriptional co-activator function can render dopaminergic neurons vulnerable to apoptosis and may contribute to the pathogenesis of Parkinson disease (1). PARK7 is an atypical peroxiredoxin-like peroxidase that scavenges hydrogen peroxide through oxidation of cys106 (2). PARK7 Protein is ideal for investigators involved in Signaling Proteins, Cell Stress & Chaperone Proteins, Apoptosis/Autophagy, Cancer, Cell Cycle, and Neurobiology research.
PARK7 Protein is stored in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol. PARK7 Protein is suitable for use in Western Blot. Expect a band approximately ~22kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.
Specifications
Specifications
- Size:20 µg
- Cat. No.:75930-732
- Shipping Temperature:Dry Ice
- Protein Synonyms:PARK7|DJ-1
- Protein/Peptide Name:PARK7
Specifications
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