Mouse IgG - Passive Blockers
About this item
A passive blocking reagent designed to reduce assay interference from human anti-mouse antibodies (HAMA) in immunoassays using mouse antibodies.
- Reduces false positives and false negatives caused by human anti-mouse antibody (HAMA) interference
- Improves assay reproducibility, particularly in complex or mixed-species formats
- Compatible with ELISA, CLIA, and lateral flow assays, including Mab/Pab systems
Passive blocking reagents function by preventing interfering antibodies from binding to capture or detection antibodies through competitive binding. Mouse IgG can be used in sandwich or competitive ELISAs and lateral flow assays that employ mouse antibodies, where human anti-mouse antibodies (HAMA) in patient samples may otherwise bind non-specifically and interfere with assay signals.
Animal IgG blockers such as mouse IgG are species-specific and typically require addition at excess concentrations to effectively neutralize interference. In assays involving multiple antibody hosts, more than one passive blocker may be required depending on the species of both capture and detection antibodies, and overall effectiveness depends on the affinity of the interfering antibodies present in the sample.
Meridian's animal IgG reagents are produced with an emphasis on lot-to-lot consistency, scalability, and traceability, making them suitable for both research use and diagnostic assay development. Multiple species options are available to allow assay designers to match the blocker to their specific antibody system and improve assay performance and reproducibility.
Concentration: 9 to 13 mg/ml
Purification method: Protein A Chromatography. Product is 0.2 µm filtered
Storage buffer: 10 mM Sodium Phosphate, 150 mM Sodium Chloride, pH 7.0 to 7.4
Storage temperature: −30 to −10 °C
Form: Purified, liquid
Delivery information: Ship on dry ice. Store at −30 to −10 °C.Partial thawing during shipment will not affect product performance. Slight precipitation may occur on storage which can be removed by centrifugation and/or filtration and should not affect performance.
Caution: Centrifuge before opening to ensure complete recovery of vial contents.
4 Options Available Below
- Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
- Return Policy
Product Details & Documents
A passive blocking reagent designed to reduce assay interference from human anti-mouse antibodies (HAMA) in immunoassays using mouse antibodies.
- Reduces false positives and false negatives caused by human anti-mouse antibody (HAMA) interference
- Improves assay reproducibility, particularly in complex or mixed-species formats
- Compatible with ELISA, CLIA, and lateral flow assays, including Mab/Pab systems
Passive blocking reagents function by preventing interfering antibodies from binding to capture or detection antibodies through competitive binding. Mouse IgG can be used in sandwich or competitive ELISAs and lateral flow assays that employ mouse antibodies, where human anti-mouse antibodies (HAMA) in patient samples may otherwise bind non-specifically and interfere with assay signals.
Animal IgG blockers such as mouse IgG are species-specific and typically require addition at excess concentrations to effectively neutralize interference. In assays involving multiple antibody hosts, more than one passive blocker may be required depending on the species of both capture and detection antibodies, and overall effectiveness depends on the affinity of the interfering antibodies present in the sample.
Meridian's animal IgG reagents are produced with an emphasis on lot-to-lot consistency, scalability, and traceability, making them suitable for both research use and diagnostic assay development. Multiple species options are available to allow assay designers to match the blocker to their specific antibody system and improve assay performance and reproducibility.
Concentration: 9 to 13 mg/ml
Purification method: Protein A Chromatography. Product is 0.2 µm filtered
Storage buffer: 10 mM Sodium Phosphate, 150 mM Sodium Chloride, pH 7.0 to 7.4
Storage temperature: −30 to −10 °C
Form: Purified, liquid
Delivery information: Ship on dry ice. Store at −30 to −10 °C.Partial thawing during shipment will not affect product performance. Slight precipitation may occur on storage which can be removed by centrifugation and/or filtration and should not affect performance.
Caution: Centrifuge before opening to ensure complete recovery of vial contents.
Product Family Options
Product Information
- DetailsAvailabilityPrice
- Supplier Number: A66186M-0.02Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:New ProductNew Product
- Supplier Number: A66186M-1Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:New ProductNew Product
- Supplier Number: A66186M-NA-0.02Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:New ProductNew Product
- Supplier Number: A66186M-NA-1Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:New ProductNew Product
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