The PA 800S Plus system enables a wide range of analyses for characterization of monoclonal antibodies and other proteins and peptides, as well as nucleic acids, proteins and viruses used in vaccines and cell and gene therapy. Confidently safeguard the success of your biologics pipeline from discovery through QC with robust, sensitive, quantitative analyses. Ideal for global, multi-user and multi-instrument environments, you can easily transfer methods using automated, kit-based assays and lot-controlled SCIEX Pre-Built EZ-cartridges.

• High resolution separation module with temperature controlled sample storage
• High-sensitivity PDA detection

The PA 800 S Plus pharmaceutical analysis system supports the following validated applications. Required* detector configurations are noted below in certain application descriptions.

Monoclonal antibody applications:
Purity/heterogeneity with gold standard CE-SDS in minutes
Charge heterogeneity with fast and simple CZE or hi-res cIEF* (UV)

Peptides and proteins beyond mAbs:
ADCs
Fusion proteins
Hormones

Cell and gene therapy applications:
Virus particle quantitation
Viral capsid protein purity* (LIF)
Viral vector impurity analysis (empty/full)* (UV)
Transgene integrity analysis* (LIF)
Nucleic acid and plasmid purity analysis* (LIF)