Human, Mouse, Rat Recombinant GDF-11 (from E. coli)
New Product
Growth differentiation factor 11 (GDF-11), also known as bone morphogenetic protein 11 (BMP-11), is a regulator of cell growth and differentiation during muscular and neural development. GDF-11 binds the transforming growth factor-beta receptors ALK4, ALK5, and ALK7 to activate SMAD signaling. In adults, exogenous GDF-11 promotes cardiomyocyte regeneration to reverse age-related cardiac hypertrophy.
- High quality
- Low endotoxin
- Affordable
: For research use only.
- Conjugation:Unconjugated
- Protein Function:Cytokine
- Protein/Peptide Type:Recombinant
- Source:E. coli
- Species:HumanMouseRat
- Storage Conditions:At or below –20 °C
- Endotoxin Content:Endotoxin LAL (EU/µg) ≤0.1
- Biological Activity:Bioactivity assay: Alkaline phosphatase activity in ATDC5 cells; ED50 ≤100 ng/ml; Bioactivity ≥1.0×10⁴ units/mg
- Gene ID:O95390/Q9Z1W4/Q9Z217
- Reconstitution Instructions:Sterile 10 mM HCl at 0.1 mg/ml
- Endotoxin-free:N
- Carrier-Free:Y
- Protease-free:N
- Animal-Free:Y
- Protein Synonyms:BMP-11
- Protein/Peptide Name:GDF-11
- Purity:≥95%
- Molecular Weight:12.5/24.9 kDa
- Sequence:NLGLDCDEHS SESRCCRYPL TVDFEAFGWD WIIAPKRYKA NYCSGQCEYM FMQKYPHTHL VQQANPRGSA GPCCTPTKMS PINMLYFNDK QQIIYGKIPG MVVDRCGCS
- Endotoxin Level:Low
- Formulation:0.1% trifluoroacetic acid (TFA)
- Nuclease-free:N
- Grade:RUO
- Shipping Temperature:RT
- Tested Applications:Bioassay