Human Recombinant GDF-15 (from E. coli)
About this item
Growth differentiation factor 15 (GDF-15) is a member of the transforming growth factor beta (TGF-β) family and is made by the placenta and cardiovascular tissues. GDF-15 regulates inflammatory and apoptotic pathways during cellular stress and injury.
- High quality
- Low endotoxin
- Affordable
GDF-15 is emerging as a biomarker of early heart disease, such that increased levels of circulating GDF-15 are associated with an increased risk of developing heart failure.
Caution: For research use only.
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- Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
- Return Policy
Product Details & Documents
Growth differentiation factor 15 (GDF-15) is a member of the transforming growth factor beta (TGF-β) family and is made by the placenta and cardiovascular tissues. GDF-15 regulates inflammatory and apoptotic pathways during cellular stress and injury.
- High quality
- Low endotoxin
- Affordable
GDF-15 is emerging as a biomarker of early heart disease, such that increased levels of circulating GDF-15 are associated with an increased risk of developing heart failure.
Caution: For research use only.
Documents
VWR Cytokine and Growth Factors.pdf
Product Literature
Specifications for Product Family
Specifications
Specifications
- Catalog No:
- 77750-690
- 77750-692
- 77750-694
- 77750-696
- 77750-698
- Protein/Peptide Name:
- GDF-15
- GDF-15
- GDF-15
- GDF-15
- GDF-15
- Protein Synonyms:
- MIC-1|Placental TGF-β|Prostate differentiation factor
- MIC-1|Placental TGF-β|Prostate differentiation factor
- MIC-1|Placental TGF-β|Prostate differentiation factor
- MIC-1|Placental TGF-β|Prostate differentiation factor
- MIC-1|Placental TGF-β|Prostate differentiation factor
- Protein/Peptide Type:
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Protein Function:
- Cytokine
- Cytokine
- Cytokine
- Cytokine
- Cytokine
- Species:
- Human
- Human
- Human
- Human
- Human
- Source:
- E. coli
- E. coli
- E. coli
- E. coli
- E. coli
- Conjugation:
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Gene ID:
- Q99988
- Q99988
- Q99988
- Q99988
- Q99988
- Sequence:
- MARNGDHCPL GPGRCCRLHT VRASLEDLGW ADWVLSPREV QVTMCIGACP SQFRAANMHA QIKTSLHRLK PDTVPAPCCV PASYNPMVLIQKTDTGVSLQ TYDDLLAKDC HCI
- MARNGDHCPL GPGRCCRLHT VRASLEDLGW ADWVLSPREV QVTMCIGACP SQFRAANMHA QIKTSLHRLK PDTVPAPCCV PASYNPMVLIQKTDTGVSLQ TYDDLLAKDC HCI
- MARNGDHCPL GPGRCCRLHT VRASLEDLGW ADWVLSPREV QVTMCIGACP SQFRAANMHA QIKTSLHRLK PDTVPAPCCV PASYNPMVLIQKTDTGVSLQ TYDDLLAKDC HCI
- MARNGDHCPL GPGRCCRLHT VRASLEDLGW ADWVLSPREV QVTMCIGACP SQFRAANMHA QIKTSLHRLK PDTVPAPCCV PASYNPMVLIQKTDTGVSLQ TYDDLLAKDC HCI
- MARNGDHCPL GPGRCCRLHT VRASLEDLGW ADWVLSPREV QVTMCIGACP SQFRAANMHA QIKTSLHRLK PDTVPAPCCV PASYNPMVLIQKTDTGVSLQ TYDDLLAKDC HCI
- Protease-free:
- N
- N
- N
- N
- N
- Animal-Free:
- N
- N
- N
- N
- N
- Nuclease-free:
- N
- N
- N
- N
- N
- Carrier-Free:
- Y
- Y
- Y
- Y
- Y
- Endotoxin-free:
- N
- N
- N
- N
- N
- Endotoxin Level:
- Low
- Low
- Low
- Low
- Low
- Endotoxin Content:
- Endotoxin LAL (EU/µg) ≤0.1
- Endotoxin LAL (EU/µg) ≤0.1
- Endotoxin LAL (EU/µg) ≤0.1
- Endotoxin LAL (EU/µg) ≤0.1
- Endotoxin LAL (EU/µg) ≤0.1
- Biological Activity:
- Bioactivity: No biological activity data is available at this time
- Bioactivity: No biological activity data is available at this time
- Bioactivity: No biological activity data is available at this time
- Bioactivity: No biological activity data is available at this time
- Bioactivity assay: NR6R-3T3 cell proliferation; ED50 ≤20 ng/ml; Bioactivity ≥5.0×10⁴ units/mg
- Purity:
- ≥95%
- ≥95%
- ≥95%
- ≥95%
- ≥95%
- Grade:
- RUO
- RUO
- RUO
- RUO
- RUO
- Formulation:
- 0.1% Trifluoroacetic Acid (TFA)
- 0.1% Trifluoroacetic Acid (TFA)
- 0.1% Trifluoroacetic Acid (TFA)
- 0.1% Trifluoroacetic Acid (TFA)
- 0.1% Trifluoroacetic Acid (TFA)
- Molecular Weight:
- 12.4/24.8 kDa
- 12.4/24.8 kDa
- 12.4/24.8 kDa
- 12.4/24.8 kDa
- 12.4/24.8 kDa
- Reconstitution Instructions:
- Sterile water at 0.1 mg/ml
- Sterile water at 0.1 mg/ml
- Sterile water at 0.1 mg/ml
- Sterile water at 0.1 mg/ml
- Sterile water at 0.1 mg/ml
- Storage Conditions:
- –20 °C
- –20 °C
- –20 °C
- –20 °C
- –20 °C
- Shipping Temperature:
- RT
- RT
- RT
- RT
- RT
- Tested Applications:
- Bioassay
Specifications
Product Family Options
Product Information
- Pack typeSizeAvailabilityPrice
- Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:
More
Specifications
Cat. No.77750-690Protein/Peptide NameGDF-15Protein SynonymsMIC-1|Placental TGF-β|Prostate differentiation factorProtein/Peptide TypeRecombinantProtein FunctionCytokineSpeciesHumanSourceE. coliConjugationUnconjugatedGene IDQ99988SequenceMARNGDHCPL GPGRCCRLHT VRASLEDLGW ADWVLSPREV QVTMCIGACP SQFRAANMHA QIKTSLHRLK PDTVPAPCCV PASYNPMVLIQKTDTGVSLQ TYDDLLAKDC HCIProtease-freeNAnimal-FreeNNuclease-freeNCarrier-FreeYEndotoxin-freeNEndotoxin LevelLowEndotoxin ContentEndotoxin LAL (EU/µg) ≤0.1Biological ActivityBioactivity: No biological activity data is available at this timePurity≥95%GradeRUOFormulation0.1% Trifluoroacetic Acid (TFA)Molecular Weight12.4/24.8 kDaReconstitution InstructionsSterile water at 0.1 mg/mlStorage Conditions–20 °CShipping TemperatureRTTested Applications - Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:
More
Specifications
Cat. No.77750-692Protein/Peptide NameGDF-15Protein SynonymsMIC-1|Placental TGF-β|Prostate differentiation factorProtein/Peptide TypeRecombinantProtein FunctionCytokineSpeciesHumanSourceE. coliConjugationUnconjugatedGene IDQ99988SequenceMARNGDHCPL GPGRCCRLHT VRASLEDLGW ADWVLSPREV QVTMCIGACP SQFRAANMHA QIKTSLHRLK PDTVPAPCCV PASYNPMVLIQKTDTGVSLQ TYDDLLAKDC HCIProtease-freeNAnimal-FreeNNuclease-freeNCarrier-FreeYEndotoxin-freeNEndotoxin LevelLowEndotoxin ContentEndotoxin LAL (EU/µg) ≤0.1Biological ActivityBioactivity: No biological activity data is available at this timePurity≥95%GradeRUOFormulation0.1% Trifluoroacetic Acid (TFA)Molecular Weight12.4/24.8 kDaReconstitution InstructionsSterile water at 0.1 mg/mlStorage Conditions–20 °CShipping TemperatureRTTested Applications - Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:
More
Specifications
Cat. No.77750-694Protein/Peptide NameGDF-15Protein SynonymsMIC-1|Placental TGF-β|Prostate differentiation factorProtein/Peptide TypeRecombinantProtein FunctionCytokineSpeciesHumanSourceE. coliConjugationUnconjugatedGene IDQ99988SequenceMARNGDHCPL GPGRCCRLHT VRASLEDLGW ADWVLSPREV QVTMCIGACP SQFRAANMHA QIKTSLHRLK PDTVPAPCCV PASYNPMVLIQKTDTGVSLQ TYDDLLAKDC HCIProtease-freeNAnimal-FreeNNuclease-freeNCarrier-FreeYEndotoxin-freeNEndotoxin LevelLowEndotoxin ContentEndotoxin LAL (EU/µg) ≤0.1Biological ActivityBioactivity: No biological activity data is available at this timePurity≥95%GradeRUOFormulation0.1% Trifluoroacetic Acid (TFA)Molecular Weight12.4/24.8 kDaReconstitution InstructionsSterile water at 0.1 mg/mlStorage Conditions–20 °CShipping TemperatureRTTested Applications - Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:
More
Specifications
Cat. No.77750-696Protein/Peptide NameGDF-15Protein SynonymsMIC-1|Placental TGF-β|Prostate differentiation factorProtein/Peptide TypeRecombinantProtein FunctionCytokineSpeciesHumanSourceE. coliConjugationUnconjugatedGene IDQ99988SequenceMARNGDHCPL GPGRCCRLHT VRASLEDLGW ADWVLSPREV QVTMCIGACP SQFRAANMHA QIKTSLHRLK PDTVPAPCCV PASYNPMVLIQKTDTGVSLQ TYDDLLAKDC HCIProtease-freeNAnimal-FreeNNuclease-freeNCarrier-FreeYEndotoxin-freeNEndotoxin LevelLowEndotoxin ContentEndotoxin LAL (EU/µg) ≤0.1Biological ActivityBioactivity: No biological activity data is available at this timePurity≥95%GradeRUOFormulation0.1% Trifluoroacetic Acid (TFA)Molecular Weight12.4/24.8 kDaReconstitution InstructionsSterile water at 0.1 mg/mlStorage Conditions–20 °CShipping TemperatureRTTested Applications - Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:
More
Specifications
Cat. No.77750-698Protein/Peptide NameGDF-15Protein SynonymsMIC-1|Placental TGF-β|Prostate differentiation factorProtein/Peptide TypeRecombinantProtein FunctionCytokineSpeciesHumanSourceE. coliConjugationUnconjugatedGene IDQ99988SequenceMARNGDHCPL GPGRCCRLHT VRASLEDLGW ADWVLSPREV QVTMCIGACP SQFRAANMHA QIKTSLHRLK PDTVPAPCCV PASYNPMVLIQKTDTGVSLQ TYDDLLAKDC HCIProtease-freeNAnimal-FreeNNuclease-freeNCarrier-FreeYEndotoxin-freeNEndotoxin LevelLowEndotoxin ContentEndotoxin LAL (EU/µg) ≤0.1Biological ActivityBioactivity assay: NR6R-3T3 cell proliferation; ED50 ≤20 ng/ml; Bioactivity ≥5.0×10⁴ units/mgPurity≥95%GradeRUOFormulation0.1% Trifluoroacetic Acid (TFA)Molecular Weight12.4/24.8 kDaReconstitution InstructionsSterile water at 0.1 mg/mlStorage Conditions–20 °CShipping TemperatureRTTested ApplicationsBioassay
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