Eg5 Inhibitor VII

New Product

Eg5 Inhibitor VII

New Product

About this item

Eg5 Inhibitor VII is a cell-permeable quinolinone compound that acts as a very potent and selective Eg5/KSP inhibitor by antagonizing ATP binding via an allosteric site. Eg5 Inhibitor VII effectively induces monopolar spindles in ovarian adenocarcinoma SKOV3 cells, and inhibits the proliferation of colorectal carcinoma HCT116 cells. Eg5 Inhibitor VII is not competitive with respect to microtubule and exhibits minimal activity against a panel of 7 other mitotic kinesins.application：Eg5 Inhibitor VII is a very potent and selective Eg5/KSP inhibitor.

Density: 1.28 g/cm³ Boiling Point: 429.46 °C(1013 hPa) Melting Point: 172.13 °C

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Specifications

CAS No.:
912953-25-4
Storage Conditions:
Refrigerator
Protein Synonyms:
KSP Inhibitor VII| 6-(4-Trifluoromethyl)phenyl)-3,4-dihydro-2(1H)-quinolinone, GSK-1|6-(4-(trifluoromethyl)phenyl)-3,4-dihydroquinolin-2(1H)-one
Protein/Peptide Name:
Eg5 Inhibitor VII
Purity:
≥98%
Molecular Weight:
291.3 g/mol
Molecular Formula:
C₁₆H₁₂F₃NO