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- Antibody Type:Primary
- Antigen Name:5'-deoxyribose-5-phosphate lyase Ku70
- Antigen Symbol:Ku70
- Clonality:Monoclonal
- Clone:162
- Conjugation:Unconjugated
- Flow Cytometry:Yes
- Host:Mouse
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- ImmunoPrecipitation:Yes
- Isotype:IgG2a
- Reactivity:Human
- Size:500 µL
- Environmentally Preferable:
- Antigen Synonyms:CTC box binding factor 75 kDa subunit|DNA repair protein XRCC6|lupus Ku autoantigen protein p70|thyroid|Ku autoantigen|70 kDa subunit of Ku antigen|Ku autoantigen p70 subunit|70 kDa subunit|ATP-dependent DNA helicase II|5'-dRP lyase Ku70|5'-deoxyribose-5-phosphate lyase Ku70|CTC box-binding factor 75 kDa subunit|70kDa,X-ray repair cross-complementing protein 6|ATP-dependent DNA helicase 2 subunit 1|thyroid autoantigen 70kD (Ku antigen)|ATP-dependent DNA helicase II 70 kDa subunit
- Storage Buffer:10mM PBS, pH7.4, 0.2%BSA, 0.09% sodium azide
- Storage Temperature:+4°C
- Immunogen:Human B cell nuclei from plasmacytoid 2p68 cells.
- Tested Applications:Fluorescence-Activated Cell Sorting
- Purification:N/A
- Cat. No.:89351-872
- Supplier no.:GTX23108
The Ku autoantigen is a heterodimer of 70 kDa (p70) and ~80 kDa (p80) proteins. The p70 / p80 dimer is important for function of a 460 kDa DNA-dependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
Type: Primary
Antigen: Ku70
Clonality: Monoclonal
Clone: 162
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2a
Reactivity: Human