Specifications
- Antibody Type:Primary
- Antigen Name:Baculoviral Iap Repeat Containing 3
- Antigen Symbol:CIAP2
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Western Blot:Yes
- Size:50 μg
- Gene ID:330
- Antigen Synonyms:MIHC|MALT2|HAIP1|API2|AIP1|RNF49|CIAP2|HIAP1|c-IAP2
- Storage Buffer:PBS with 1 mg/ml BSA, 1.5 mM sodium azide and 50% glycerol
- Storage Temperature:Keep as concentrated solution. Store at 4 °C short term. For extended storage aliquot and store at –20 °C or below. Avoid freeze-thaw cycles.
- Concentration:0.2 mg/ml
- Immunogen:Available on request.
- Tested Applications:WB
- Purification:Immunogen affinity purified
- Cat. No.:89361-276
- Supplier no.:GTX22540
Specifications
About this item
Apoptosis can be inhibited by a group of proteins called inhibitors of apoptosis (IAPs). These proteins contain a BIR (baculovirus IAP repeat) domain near the amino-terminus. The BIR domain can bind some caspases. Many members of the IAP family of proteins block proteolytic activation of caspase-3 and ~7. For example, XIAP, cIAP 1 and cIAP 2 appear to block cytochrome c-induced activation of caspase-9, thereby preventing initiation of the caspase cascade. Since cIAP 1 and cIAP 2 were first identified as components in the cytosolic death domain-induced complex associated with the TNF family of receptors, they may inhibit apoptosis by additional mechanisms.
WB: Use at a concentration of 1 - 3 ?g/ml. In Western blot, this antibody detects a band of approximately 68 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: CIAP2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: