- Antibody Type:Primary
- Antigen Name:Neuregulin 1
- Antigen Symbol:NRG1
- Clonality:Monoclonal
- Clone:7D5
- Conjugation:Unconjugated
- Host:Mouse
- ImmunoChemistry:Yes
- ImmunoPrecipitation:Yes
- Isotype:IgG2a
- Reactivity:Mouse
- Western Blot:Yes
- Size:500 μl
- Gene ID:112400
- Antigen Synonyms:sensory and motor neuron derived factor|pro-NRG1|HRG1|alpha (45kD|membrane-bound isoform|NDF|glial growth factor|SMDF|MSTP131|ARIA|NRG1-IT2|pro-neuregulin-1|HRG|ERBB2 p185-activator)|GGF2|MST131|GGF|heregulin|neu differentiation factor|HRGA|HGL
- Storage Buffer:Phosphate-buffered saline, pH 7.2, containing 0.05% sodium azide
- Storage Temperature:Store at 4-8 °C.
- Immunogen:Recombinant extracellular domain of rat NDF protein.
- Tested Applications:IHC-P, IHC-Fr, IP, WB
- Purification:IgG fraction
- Cat. No.:89351-786
- Supplier no.:GTX22369
Heregulin binds to e-erbB-3 and c-erbB-4 receptors on mammary and neuronal cells with low and high affinities, respectively. HRG/NDF exists in several isoforms, which are classified in two groups, a and b, that differ in their EGF-like domain and in receptor binding affinity.
IHC: This antibody may be diluted to a titer of 1:50-1:100 in an ABC method. We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions and antibody dilutions should be determined by the user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining.
Type: Primary
Antigen: NRG1
Clonality: Monoclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2a
Reactivity: Mouse