- Antibody Type:Primary
- Antigen Name:8-Oxoguanine glycosylase
- Antigen Symbol:OGG1
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human
- Western Blot:Yes
- Size:100 μl
- Gene ID:4968
- Antigen Synonyms:OGH1|HMMH|MUTM|HOGG1|CGL-2|CCP-X|CTLA1|CTSGL2|CSP-C
- Storage Buffer:PBS with 0.05% sodium azide
- Storage Temperature:Keep as concentrated solution, aliquot and store at 4°C. Do not freeze.
- Concentration:1 mg/ml
- Immunogen:Synthetic peptide: CTVYRGDKSQASRPT conjugated to KLH, corresponding to amino acids 65-79 of Human Ogg 1.
- Tested Applications:IHC-P, IHC-Fr, WB
- Purification:Immunogen affinity purified
- Cat. No.:89351-518
- Supplier no.:GTX20204
This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. The N-terminus of this gene contains a mitochondrial targetting signal, essential for mitochondrial localization.
WB: Use at a dilution of 1/500-1000.ICC/IF: Use at a dilution of 1/100-200.IHC-P: Use at a dilution of 1/100.IHC-Fr: Use at a dilution of 1/25-100. IP: Use at a dilution of 1/10-500.Predicted molecular weight: 39 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: OGG1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human