G-Biosciences' Immobilized Pepstatin is for the purification of cathepsins, pepsin, bacterial aspartic proteases, HIV proteases and other molecules that bind pepstatin.

Pepstatin is isovaleryl-Val-Val-AHMHA-Ala-AHMHA, where AHMHA= (3S, 4S)-4-amino-3-hydroxy-6-methyl-heptanoic acid and is a potent inhibitor of various aspartic proteases, including cathepsin D, renin, pepsin, bacterial aspartic proteases and HIV proteases.

G-Biosciences' Immobilized Pepstatin resin consists of 6% beaded agarose that is covalently coupled to pepstatin through a diaminodipropylamine spacer arm and has a binding capacity of 1 to 2 mg pepsin per millimeter of settled resin.