Non-ionic detergents have a hydrophilic head group that is uncharged and are preferred for their ability to break lipid-lipid and lipid-protein interactions.
The non-ionic deteregents are supplied as a general Research Grade, Proteomic Grade (PG) Solutions and 2D-Detergents™. The Proteomic Grade (PG) Solutions have ultra low aldehyde (<100 μM) and peroxide (<50 μM) concentrations to reduce the effects of peroxidase and carbonyl compounds that negatively interact with membrane proteins. The 2D-Detergents™ have low conductivity (<10 μS) and ultra low aldehyde (<100 μM) and peroxide (<50 μM) concentrations.
G-Biosciences Non-Ionic Detergent Solutions include: Triton® X-100, Triton® X-114, Brij® 35, Brij® 58, Tween® 20, Tween® 80, Nonidet® P-40 Substitute, Octyl ß Glucoside, MEGA 8, MEGA 9, MEGA 10, BigCHAP, and Deoxy Big CHAP.
They have limited ability to break protein-protein interactions and are often referred to as non-denaturing detergents and are used to isolate biologically active membrane proteins.
To order chemicals, medical devices, or other restricted products please provide ID that includes your business name & shipping address via email [email protected] or fax 484.881.5997 referencing your VWR account number. Acceptable forms of ID are:
- • State issued document with your organization's Federal Tax ID Number
- • State issued document with your organization's Resale Tax ID Number
- • City or County issued Business License
- • State Department of Health Services License
- • Any other ID issued by the State that includes the business name & address
* ATTN: California Customers may require additional documentation as part of the CA Health & Safety Code. Products that fall under this regulation will be placed on a mandatory 21-day hold after documentation is received. Avantor will not lift restrictions for residential shipping addresses.