Human Recombinant FLT-3 (CTGrade GMP) (from E. coli)
Supplier: FUJIFILM IRVINE SCIENTIFIC, INC
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About this item
IL-6 is an important pro-inflammatory and anti-inflammatory cytokine expressed by T cells, macrophages, and muscle cells. Signals through a receptor complex containing two receptors, IL-6Rα and gp130. Plays an important function in promoting fever and can serve to stimulate an immune response to trauma.
- High quality
- Low endotoxin
- Lot-to-lot consistency
- Animal free
- Manufactured following GMP guidelines
IL-6 is often used for growth of hybridoma cell lines. The biological activity of CTGrade GMP interleukins and growth factors is standardized, where applicable, to WHO International standards, providing cell and gene therapy developers consistent, lot-to-lot biological activity and performance.
Host cell protein: ≤30 ng/ml
Host cell DNA: ≤0.01 ng/ml
Sterility testing: No growth
Mycoplasma: Negative
Caution: For research use or further manufacturing only.
Specifications
- Conjugation:Unconjugated
- Protein Function:Cytokine
- Protein/Peptide Type:Recombinant
- Source:E. coli
- Species:Human
- Storage Conditions:At or below −20 °C
- Endotoxin Content:Endotoxin LAL (EU/µg) ≤0.05
- Biological Activity:Bioactivity assay: Proliferation of OCI-Aml5. ED50 ≤5 ng/ml. bioactivity ≥1.6×10³ IU/µg
- Gene ID:P49771
- Reconstitution Instructions:Sterile water at 0.1 - 0.5 mg/ml
- Endotoxin-free:N
- Carrier-Free:Y
- Protease-free:N
- Animal-Free:Y
- Protein Synonyms:Flt3L|Fms-related tyrosine kinase 3 ligand
- Protein/Peptide Name:CTGrade GMP FLT-3 Ligand
- Purity:≥97%
- Molecular Weight:17.7 kDa
- Sequence:MTQDCSFQHS PISSDFAVKI RELSDYLLQD YPVTVASNLQ DEELCGGLWR LVLAQRWMER LKTVAGSKMQ GLLERVNTEI HFVTKCAFQP PPSCLRFVQT NISRLLQETS EQLVALKPWI TRQNFSRCLE LQCQPDSSTL PPPWSPRPLE ATAPT
- Endotoxin Level:Low
- Formulation:10 mM sodium phosphate, 50 mM sodium chloride, pH 8.0
- Nuclease-free:N
- Grade:GMP
- Shipping Temperature:Ambient
- Tested Applications:Bioassay