Human/Mouse Recombinant/M NT-3 (from E. coli)
Supplier: FUJIFILM IRVINE SCIENTIFIC, INC
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About this item
Neurotrophin-3 (NT-3) is an important member of the nerve growth factor (NGF) family of proteins. NT-3 promotes the growth, survival, and differentiation of neurons and synapses in the peripheral and central nervous systems. The receptor tyrosine kinase TrkC exclusively binds in high-affinity to NT-3. NT-3 also signals through the receptor tyrosine kinase TrkB, and through the low affinity nerve growth factor receptor (LNGFR).
- High quality
- Low endotoxin
- Affordable
Caution: For research use only.
Specifications
- Conjugation:Unconjugated
- Protein Function:Cytokine
- Protein/Peptide Type:Recombinant
- Source:E. coli
- Species:HumanMouse
- Storage Conditions:At or below −20 °C
- Endotoxin Content:Endotoxin LAL (EU/µg) ≤0.1
- Biological Activity:Bioactivity assay: Proliferation of a neuroblastoma cell line stably expressing TrkB (BR6). ED50 ≤20 ng/ml. bioactivity ≥5.0×10⁴ units/mg
- Gene ID:P20783/P20181
- Reconstitution Instructions:Sterile water at 0.1 mg/ml
- Endotoxin-free:N
- Carrier-Free:Y
- Protease-free:N
- Animal-Free:N
- Protein Synonyms:nerve growth factor 2 (NGF-2)|HGNF|neurotrophic factor|NT3|Neurotrophin 3
- Accession No.:P20783/P20181
- Protein/Peptide Name:NT-3
- Purity:≥95%
- Molecular Weight:13.8/27.5 kDa
- Sequence:MYAEHKSHRG EYSVCDSESL WVTDKSSAID IRGHQVTVLG EIKTGNSPVK QYFYETRCKE ARPVKNGCRG IDDKHWNSQC KTSQTYVRAL TSENNKLVGW RWIRIDTSCV CALSRKIGRT
- Endotoxin Level:Low
- Formulation:0.1% Trifluoroacetic Acid (TFA)
- Nuclease-free:N
- Grade:RUO
- Shipping Temperature:RT
- Tested Applications:Bioassay