Horse Recombinant PDGF-BB (from E. coli)
Supplier: FUJIFILM IRVINE SCIENTIFIC, INC
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About this item
Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-α, TGF-β, and EGF signaling.PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells. PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues. PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-α and PDGFR-β.
- High quality
- Low endotoxin
- Affordable
Caution: For research use only.
Specifications
- Conjugation:Unconjugated
- Protein Function:Cytokine
- Protein/Peptide Type:Recombinant
- Source:E. coli
- Species:Horse
- Storage Conditions:–20 °C
- Endotoxin Content:Endotoxin LAL (EU/µg) ≤0.1
- Biological Activity:Bioactivity Assay: NR6R 3T3 proliferation, ED₅₀ ≤30 ng/ml, Bioactivity ≥3.3×10⁴ units/mg
- Gene ID:XP_005606703
- Amino Acid Number:110/220
- Reconstitution Instructions:Sterile water at 0.1 mg/ml
- Endotoxin-free:N
- Carrier-Free:Y
- Protease-free:N
- Animal-Free:N
- Protein Synonyms:ODGF|GDGF
- Protein/Peptide Name:PDGF-BB
- Purity:≥95%
- Molecular Weight:24.8 kDa
- Sequence:MSLGSLAVAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRHVQ CRPTQVQLRP VQVRKIEIVR KKPTFKKATV TLEDHLACKC ETVGAARPVT
- Endotoxin Level:Low
- Formulation:10 mM Sodium phosphate, pH 7.5
- Nuclease-free:N
- Grade:RUO
- Shipping Temperature:RT
- Tested Applications:Bioassay