Sephadex G-10 is a well established gel filtration medium for desalting and buffer exchange of peptides and small biomolecules >700 molecular weight.

• Quickly desalts, removes contaminants and transfers to a new buffer in a single step
• Suitable for buffer exchange and cleanup of biological samples, for example peptides, small proteins, and oligosaccharides larger than 700 molecular weight
• Efficient removal of contaminants such as salts, dyes, and radioactive labels
• Lowest exclusion limit (700 molecular weight) in the Sephadex G-range

Sephadex is a gel filtration medium prepared by crosslinking dextran with epichlorohydrin. Different types of Sephadex differ in their degree of cross-linking and hence in their degree of swelling and their molecular fractionation range. Sephadex G-10 is one of six different G-types ranging from G-10 for small molecules to G-100 for very large biomolecules.