This assay has high sensitivity and excellent specificity for detecting Rat Ab1 to 42 (Amyloid Beta Peptide 1 to 42). The assay range is from 3.70 to 300 pg/ml (Competitive kit) with a sensitivity of 1.61 pg/ml. There is no detectable cross to reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.

• High sensitivity and specificity
• Perfect reproducibility and consistency across batches
• Quality control with three-level inspections
• Wide range of targets/species available
• Intra-Assay: CV <10%, Inter-Assay: CV <12%

One of the hallmarks of Alzheimer's disease is the self-aggregation of the amyloid β peptide (Aβ) in extracellular amyloid fibrils. Aβ is a peptide composed of 40 to 42 (43) amino acids, and is said to be cleaved out of the precursor protein APP by the action of β- or γ-secretase.In addition, the presence of numerous variant A β molecules has been demonstrated in the culture fluid of mouse neuroblastoma cells transfected with cDNA coding human amyloid precursor protein (APP). Among the different forms of Aβ, the 42-residue fragment (Aβ1-42) readily self-associates and forms nucleation centers from where fibrils can quickly grow. The strong tendency of Aβ1-42 to aggregate is one of the reasons for the scarcity of data on its fibril formation process. Aβ1-40 is the most common form secreted from cultured cells and found in cerebro-spinal fluid (CSF). Aβ1-42 is the major component of senile plaques and considered as the most crucial factor in AD pathogenesis.