This assay has high sensitivity and excellent specificity for detecting Pig IGFBP7 (Insulin Like Growth Factor Binding Protein 7). The assay range is from 0.312 to 20 ng/ml (Sandwich kit) with a sensitivity of 0.135 ng/ml. There is no detectable cross to reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.

• High sensitivity and specificity
• Perfect reproducibility and consistency across batches
• Quality control with three-level inspections
• Wide range of targets/species available
• Intra-Assay: CV <10%, Inter-Assay: CV <12%

By Northern blot analysis, Oh et al. (1996) found that mac25, or IGFBP7, wajs expressed as a 1.1-kb transcript in a broad spectrum of normal tissues. These authors reported that the predicted 277-amino acid protein contains a 26-amino acid signal sequence and the IGFBP motif (GCGCCXXC) at the N terminus. The IGFBP motif is located in a region containing a cluster of 12 conserved cysteines, of which 11 are found in IGFBP7. The amino acid sequences of IGFBP7 and IGFBPs share 20 to 25% identity. Oh et al. (1996) found that recombinant IGFBP7 specifically bound IGFs, although with relatively low affinity. Kim et al. (1997) proposed that IGFBP7, CTGF, NOV, and IGFBP10  constitute a subfamily of low-affinity IGFBPs.