Specifications
- Assay duration:Multiple steps
- Assay Type (ELISA with LOV):Sandwich
- Conjugate ELISA:Biotin
- Format:Pre-coated
- Host:Rabbit
- Primary antibody reactivity:Mouse
- Target protein:MRC1
- Size:1 Kit
- Sample Type:Serum, plasma, tissue homogenates, cell lysates and other biological fluids
- Cross Reactivity:No significant cross-reactivity or interference between Mannose Receptor C Type 1 (MRC1) and analogues was observed
- Detection Method:Colorimetric
- Time to Results:3 h
- Shelf Life:12 Months
- Detection Range:15.6 - 1000 pg/ml
- Storage Temperature:4 °C for one month (frequent use), −20 °C for one year
- Sample Volume:100 µl
- Sensitivity:6.1 pg/ml
- Regulatory Status:RUO
- Cat. No.:MSPP-SEB542MU
- No. of tests:96 wells
Specifications
About this item
This assay has high sensitivity and excellent specificity for detecting Mouse MRC1 (Mannose Receptor C Type 1). The assay range is from 15.6 to 1000 pg/ml (Sandwich kit) with a sensitivity of 6.1 pg/ml. There is no detectable cross to reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.
- High sensitivity and specificity
- Perfect reproducibility and consistency across batches
- Quality control with three-level inspections
- Wide range of targets/species available
- Intra-Assay: CV <10%, Inter-Assay: CV <12%
The mannose receptor found on macrophages and on endothelial cells of the liver is the only known example of a C-type lectin that contains multiple C-type CRDs. One function of the receptor is to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi, so that they can be neutralized by phagocytic engulfment.,Kim et al. characterized the gene for the human macrophage mannose receptor (MRC1) by isolation of clones covering the entire coding region. MRC1 was demonstrated to be divided into 30 exons. The first 3 exons encode the signal sequence, the NH2-terminal cysteine-rich domain, and the fibronectin type II repeat, while the final exon encodes the transmembrane anchor and the cytoplasmic tail.