This assay has high sensitivity and excellent specificity for detecting Human FGL1 (Fibrinogen Like Protein 1). The assay range is from 12.5 to 800 ng/ml (Sandwich kit) with a sensitivity of 4.4 ng/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.

• High sensitivity and specificity
• Perfect reproducibility and consistency across batches
• Quality control with three-level inspections
• Wide range of targets/species available
• Intra-assay: CV<10%; Inter-assay: CV<12%

Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. The deduced 312 amino acid FGL1 protein possesses a hydrophobic leader peptide. FGL1 shares significant sequence homology with FGB and FGG and with other fibrinogen-related proteins. The FGL1 sequence includes 4 cysteine residues that are widely conserved in all fibrinogens and fibrinogen-related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas.