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Specifications
- Assay duration:Multiple steps
- Assay Type (ELISA with LOV):Competitive
- Conjugate ELISA:Biotin
- Format:Pre-coated
- Host:Rabbit
- Primary antibody reactivity:Multiple
- Target protein:PAF
- Size:1 kit
- Sample Type:Serum, plasma and other biological fluids
- Cross Reactivity:No significant cross-reactivity or interference between Platelet Activating Factor (PAF) and analogues was observed
- Detection Method:Colorimetric
- Time to Results:2 h
- Shelf Life:12 Months
- Detection Range:37.0 - 3000 pg/ml
- Storage Temperature:4 °C for one month (frequent use), −20 °C for one year
- Sample Volume:50 µl
- Sensitivity:13.3 pg/ml
- Regulatory Status:RUO
- Cat. No.:MSPP-CEA526GE
- No. of tests:96 wells
Specifications
About this item
This assay has high sensitivity and excellent specificity for detecting General species PAF (Platelet Activating Factor). The assay range is from 37.0 to 3000 pg/ml (Competitive kit) with a sensitivity of 13.3 pg/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.
- High sensitivity and specificity
- Perfect reproducibility and consistency across batches
- Quality control with three-level inspections
- Wide range of targets/species available
- Intra-assay: CV<10%; Inter-assay: CV<12%
Platelet-activating factor is a potent phospholipid activator and mediator of many leukocyte functions, including platelet aggregation, inflammation, and anaphylaxis.It is produced in response to specific stimuli by a variety of cell types, including neutrophils, basophils, platelets, and endothelial cells.Several molecular species of platelet-activating factor have been identified which vary in the length of the O-alkyl side chain.It is an important mediator of bronchoconstriction.It causes platelets to aggregate and blood vessels to dilate. Thus it is important to the process of hemostasis. At a concentration of 10^-12 M, PAF causes life threatening inflammation of the airways to induce asthma like symptoms.Toxins such as fragments of destroyed bacteria induce the synthesis of PAF, which causes a drop in blood pressure and reduced volume of blood pumped by the heart, which leads to shock and maybe death.