Specifications
- Pack type:Vial
- Conjugation:Unconjugated
- Protein Function:Immune Checkpoint Proteins
- Source:E. coli
- Species:Human
- Size:50 µg
- Tag sequence:MGHHHHHHSGSEF
- Storage Conditions:−20 °C
- Endotoxin Content:<1.0 EU per 1 µg (determined by the LAL method)
- Gene ID:2621
- Reconstitution Instructions:Reconstitute in 10 mM PBS (pH 7.4) to a concentration of 0.1 - 1.0 mg/ml. Do not vortex.
- Endotoxin-free:N
- Carrier-Free:Y
- Protease-free:N
- Animal-Free:Y
- Protein Synonyms:Growth Arrest Specific Protein 6
- UniProtKB:Q14393
- Protein/Peptide Name:GAS6 active (prokaryotic)
- Purity:90 - 100%
- Molecular Weight:24 kDa
- Sequence:Leu136~Phe311
- Endotoxin Level:Low
- Concentration:0.2 mg/ml
- Formulation:Lyophilized from PBS, pH 7.4, containing 0.01% SKL, 5% Trehalose
- Nuclease-free:N
- Shipping Temperature:4 °C
- Tested Applications:Cell culture, Activity Assays.
- Cat. No.:MSPP-APA204HU1
Specifications
About this item
This is a GAS6 active protein (prokaryotic), Human is sequencing from Leu136~Phe311 with 90 to 100% purity. Lyophilized from PBS, pH 7.4, containing 0.01% SKL, 5% Trehalose with 0.2 mg/ml.
- High quality, purity, reproducibility and effectiveness
- Offers customized buffers and tag options
- 100% quality and service satisfaction guarantee
Growth arrest-specific 6 is similar to the Protein S with the same domain organization and 43% amino acid identity. GAS6 is a gamma-carboxyglutamic acid (Gla) domain-containing protein thought to be involved in the stimulation of cell proliferation. The gene is expressed as an abundant 2.6-kb mRNA in starved cells but decreases significantly upon stimulation of cells with serum or fibroblast growth factor. A human homolog was isolated from HeLa cells and was predicted to encode a 678-amino acid protein with 81% identity to the mouse protein and 44% identity to human protein S, a vitamin K-dependent negative coregulator in the blood coagulation pathway. Regions of greatest similarity between Gas6 and protein S occur in a gamma carboxylated glutamic acid-rich domain and in 4 EGF-like domains.