Specifications

Antibody Type:
Primary
Antigen Name:
Relaxin/Insulin Like Family Peptide Receptor 1
Antigen Symbol:
RXFP1
Clonality:
Polyclonal
Conjugation:
Unconjugated
Host:
Rabbit
ImmunoChemistry:
Yes
ImmunoPrecipitation:
Yes
Isotype:
IgG
Reactivity:
Human,
Mouse
Western Blot:
Yes
Size:
200 µl
Cross Adsorption:
No
Form:
Liquid
Gene ID:
59350
Antigen Synonyms:
RXFP1|Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 7|LGR7.1|LGR7|Relaxin family peptide receptor 1|RXFPR1|LGR7.2|Relaxin receptor 1|LGR7.10
Amino Acid Number:
260 - 409
UniProtKB:
Q9HBX9
Storage Buffer:
PBS, pH 7.4, containing 0.02% NaN₃, 50% glycerol
Molecular Weight:
17 kDa
Storage Temperature:
Store at 2...8 °C for frequent use, −20 °C for 24 months. Avoid repeated freeze-thaw cycles.
Concentration:
0.5 mg/ml (for reference only)
Shipping Temperature:
Shipped on blue ice at 4 °C
Immunogen:
Recombinant RXFP1(Pro260~Met409)
Purification:
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Cat. No.:
MSPP-PAB456HU1
Packaging:
Vial

Specifications

About this item

Polyclonal antibody to Relaxin/Insulin Like Family Peptide Receptor 1 (RXFP1), derived from recombinant RXFP1(Pro260~Met409), is reactive with Human/Mouse.

High specificity, affinity and purity
Extensive validation and batch-to-batch consistency
Diverse range of conjugated and custom options
Comprehensive validation data and documentation
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The deduced 757- and 723-amino acid LGR7 proteins are 33% identical to snail Lgr. They contain a low density lipoprotein receptor cysteine-rich motif, 10 LRRs, and 5 N-glycosylation sites in the N terminus, the 7-transmembrane region, and a unique C-terminal tail with a phosphorylation site. Northern blot analysis revealed expression of a 5.5-kb transcript in all rat tissues tested except spleen, and smaller transcripts were found in oviduct, uterus, colon, and brain. Expression of the long and short variants of LGR7 with mutations in transmembrane domain 6 (asp637 to tyr and asp603 to tyr, respectively), but not of wildtype LGR7, resulted in increased basal production of cAMP, as seen in similar experiments with the luteinizing hormone receptor (LHCGR) and the TSH receptor but not the FSH receptor.

Caution: For research use only. Not for use in clinical diagnostic procedures. Please proper stored each component based on the instruction.

Type: Primary
Antigen: RXFP1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse