- Antibody Type:Primary
- Antigen Name:Tyrosine Hydroxylase
- Antigen Symbol:TH
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoPrecipitation:Yes
- Isotype:IgG
- Reactivity:Mouse
- Western Blot:Yes
- Size:200 µl
- Cross Adsorption:No
- Form:Liquid
- Gene ID:21823
- Antigen Synonyms:DYT5b|TYH|Dystonia 14|Tyrosine 3-Monooxygenase
- Amino Acid Number:34 - 301
- UniProtKB:P24529
- Storage Buffer:0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol
- Molecular Weight:37 kDa
- Storage Temperature:Store at 2...8 °C for frequent use, −20 °C for 24 months. Avoid repeated freeze-thaw cycles.
- Concentration:0.38 mg/ml (for reference only)
- Shipping Temperature:Shipped on blue ice at 4 °C
- Immunogen:Recombinant TH(Phe34~Leu301)
- Purification:Antigen-specific affinity chromatography followed by Protein A affinity chromatography
- Cat. No.:MSPP-PAB438MU1
- Packaging:Vial
Polyclonal antibody to Tyrosine Hydroxylase (TH), derived from recombinant TH(Phe34~Leu301), is reactive with Mouse.
- High specificity, affinity and purity
- Extensive validation and batch-to-batch consistency
- Diverse range of conjugated and custom options
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Tyrosine hydroxylase or tyrosine 3-monooxygenase is the enzyme responsible for catalyzing the conversion of the amino acid L-tyrosine to dihydroxyphenylalanine (DOPA). DOPA is a precursor for dopamine which in turn is a precursor for norepinephrine (noradrenaline) and epinephrine (adrenaline). In humans, tyrosine hydroxylase is encoded by the TH gene. The enzyme, an oxygenase, is found in the cytosol of all cells containing catecholamines. This initial reaction is the rate limiting step in the production of catecholamines. The enzyme is highly specific, not accepting indole derivatives - which is unusual as many other enzymes involved in the production of catecholamines do.
Type: Primary
Antigen: TH
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Mouse