Specifications
- Antibody Type:Primary
- Antigen Name:Nuclear Mitotic Apparatus Protein 1
- Antigen Symbol:NUMA1
- Clonality:Monoclonal
- Clone:D9
- Conjugation:Unconjugated
- Host:Mouse
- ImmunoChemistry:Yes
- ImmunoPrecipitation:Yes
- Isotype:IgG1 kappa
- Reactivity:Pig,Human
- Western Blot:Yes
- Size:200 µl
- Cross Adsorption:No
- Form:Liquid
- Gene ID:4926
- Antigen Synonyms:SP-H antigen|Nuclear matrix protein-22|NUMA|NMP22
- Amino Acid Number:1700 - 2115
- UniProtKB:Q14980
- Storage Buffer:0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol
- Molecular Weight:50/56 kDa
- Storage Temperature:Store at 2...8 °C for frequent use, −20 °C for 24 months. Avoid repeated freeze-thaw cycles.
- Concentration:1 mg/ml (for reference only)
- Shipping Temperature:Shipped on blue ice at 4 °C
- Immunogen:Recombinant NUMA1(Phe1700~His2115)
- Purification:Protein A + Protein G affinity chromatography
- Cat. No.:MSPP-MAC332HU2
- Packaging:Vial
Specifications
About this item
Monoclonal antibody to Nuclear Mitotic Apparatus Protein 1 (NUMA1), derived from recombinant NUMA1(Phe1700~His2115), is reactive with Human/Pig.
- High specificity, affinity and purity
- Extensive validation and batch-to-batch consistency
- Diverse range of conjugated and custom options
- Comprehensive validation data and documentation
- All in stock and fast global delivery
- 100% Quality and service satisfaction guarantee!
The NUMA protein was one of the first to be described as a cell cycle-related protein based on a distinct immunofluorescent staining pattern: in interphase, NUMA is present throughout the nucleus, and in mitosis, it localizes to the spindle apparatus (Lydersen and Pettijohn, 1980). Some patients with autoimmune disease have antibodies directed against the NUMA protein. The full-length NUMA cDNA (Compton et al. 1992, Yang et al. 1992) predicts a protein with a calculated molecular mass of about 237 kDa, containing 2 globular domains separated by a coiled-coil domain of 1485 amino acids. Wong et al. (2006) stated that the coiled-coil region of NUMA can form parallel coiled-coil dimers. By fluorescence in situ hybridization, Sparks et al. (1993) demonstrated that the NUMA1 gene is present in single copy and located on chromosome 11q13.
Type: Primary
Antigen: NUMA1
Clonality: Monoclonal
Clone: D9
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1 Kappa
Reactivity: Human, Pig