Specifications

Antibody Type:
Primary
Antigen Name:
Breast Cancer Susceptibility Protein 2
Antigen Symbol:
BRCA2
Clonality:
Polyclonal
Conjugation:
Unconjugated
Host:
Rabbit
ImmunoChemistry:
Yes
ImmunoPrecipitation:
Yes
Isotype:
IgG
Reactivity:
Mouse
Western Blot:
Yes
Size:
200 µl
Cross Adsorption:
No
Form:
Liquid
Gene ID:
12190
Antigen Synonyms:
FAD|FANCD|BRCA2|FANCD1|FACD|Breast Cancer 2,Early Onset|FAD1|Breast Cancer Type 2 Susceptibility Protein|Fanconi anemia group D1 protein|BRCC2
Amino Acid Number:
2990 - 3232
UniProtKB:
P97929
Storage Buffer:
PBS, pH 7.4, containing 0.02% NaN₃, 50% glycerol
Molecular Weight:
30 kDa
Storage Temperature:
Store at 2...8 °C for frequent use,−20 °C for 24 months. Avoid repeated freeze-thaw cycles.
Concentration:
1 mg/ml (for reference only)
Shipping Temperature:
Shipped on blue ice at 4 °C
Immunogen:
recombinant BRCA2 (Glu2990~Ala3232)
Purification:
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Cat. No.:
MSPP-PAB364MU1
Packaging:
Vial

Specifications

About this item

Polyclonal Antibody to Breast Cancer Susceptibility Protein 2 (BRCA2), derived from recombinant BRCA2 (Glu2990~Ala3232), is reactive with Mouse.

High specificity, affinity and purity
Extensive validation and batch-to-batch consistency
Diverse range of conjugated and custom options
Comprehensive validation data and documentation
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BRCA2 is a protein belongs to the tumor suppressor gene family and the protein encoded by this gene is involved in the repair of chromosomal damage with an important role in the error-free repair of DNA double strand breaks. The BRCA2 gene is located on the long (q) arm of chromosome 13 at position 12.3 (13q12.3), from base pair 31, 787, 616 to base pair 31, 871, 804. The BRCA2 protein binds to and regulates the protein produced by the RAD51 gene to fix breaks in DNA. These breaks can be caused by natural and medical radiation or other environmental exposures, but also occur when chromosomes exchange genetic material during a special type of cell division that creates sperm and eggs (meiosis).

Caution: For research use only. Not for use in clinical diagnostic procedures. Please proper stored each component based on the instruction.

Type: Primary
Antigen: BRCA2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Mouse