Specifications
- Antibody Type:Primary
- Antigen Name:N-Terminal Pro-Brain Natriuretic Peptide
- Antigen Symbol:NT-ProBNP
- Clonality:Monoclonal
- Clone:F8
- Conjugation:Unconjugated
- Host:Mouse
- ImmunoChemistry:Yes
- ImmunoPrecipitation:Yes
- Isotype:IgG2a kappa
- Reactivity:Pig,Human
- Western Blot:Yes
- Size:200 µl
- Cross Adsorption:No
- Form:Liquid
- Gene ID:4879
- Antigen Synonyms:NT-Pro-BNP|N-BNP
- Amino Acid Number:27 - 102
- UniProtKB:P16860
- Storage Buffer:PBS, pH 7.4, containing 0.02% NaN₃, 50% glycerol
- Molecular Weight:12 kDa
- Storage Temperature:Store at 2...8 °C for frequent use,−20 °C for 24 months. Avoid repeated freeze-thaw cycles.
- Concentration:1 mg/ml (for reference only)
- Shipping Temperature:Shipped on blue ice at 4 °C
- Immunogen:recombinant NT-ProBNP (His27~Arg102)
- Purification:Protein A + Protein G affinity chromatography
- Cat. No.:MSPP-MA485HU21
- Packaging:Vial
Specifications
About this item
Monoclonal Antibody to N-Terminal Pro-Brain Natriuretic Peptide (NT-ProBNP), derived from recombinant NT-ProBNP (His27~Arg102), is reactive with Human/Pig.
- High specificity, affinity and purity
- Extensive validation and batch-to-batch consistency
- Diverse range of conjugated and custom options
- Comprehensive validation data and documentation
- All in stock and fast global delivery
- 100% Quality and service satisfaction guarantee
Brain-type Natriuretic Peptide (BNP) is a nonglycosylated peptide that is produced predominantly by ventricular myocytes and belongs to the natriuretic peptide family. Plasma NT-proBNP is a marker for congestive heart failure, while mature BNP (aa 103 to 134) promotes vasodilation and fluid and sodium excretion. BNP is co-secreted along with a 76 amino acid N-terminal fragment (NT-proBNP) which is biologically inactive. BNP binds to and activates the atrial natriuretic factor receptors NPRA, and to a lesser extent NPRB, in a fashion similar to atrial natriuretic peptide (ANP) but with 10-fold lower affinity. The biological half-life of BNP, however, is twice as long as that of ANP, and that of NT-proBNP is even longer, making these peptides better targets than ANP for diagnostic blood testing.
Type: Primary
Antigen: NT-ProBNP
Clonality: Monoclonal
Clone: F8
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2a Kappa
Reactivity: Human, Pig