Specifications
- Antibody Type:Primary
- Antigen Name:Transient Receptor Potential Cation Channel Subfamily V, Member 1
- Antigen Symbol:TRPV1
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western Blot:Yes
- Size:200 µl
- Cross Adsorption:No
- Form:Liquid
- Gene ID:7442
- Antigen Synonyms:Vanilloid Receptor Subtype 1|VR1|Vanilloid receptor 1|OTRPC1|Osm-9-like TRP channel 1|Capsaicin receptor
- Amino Acid Number:1 - 153
- UniProtKB:Q8NER1
- Storage Buffer:PBS, pH 7.4, containing 0.02% NaN₃, 50% glycerol
- Molecular Weight:24 kDa
- Storage Temperature:Store at 2...8 °C for frequent use,−20 °C for 24 months. Avoid repeated freeze-thaw cycles.
- Concentration:0.67 mg/ml (for reference only)
- Shipping Temperature:Shipped on blue ice at 4 °C
- Immunogen:recombinant TRPV1 (Met1~Glu153)
- Purification:Antigen-specific affinity chromatography followed by Protein A affinity chromatography
- Cat. No.:MSPP-PAF839HU1
- Packaging:Vial
Specifications
About this item
Polyclonal Antibody to Transient Receptor Potential Cation Channel Subfamily V, Member 1 (TRPV1), derived from recombinant TRPV1 (Met1~Glu153), is reactive with Human/Mouse/Rat.
- High specificity, affinity and purity
- Extensive validation and batch-to-batch consistency
- Diverse range of conjugated and custom options
- Comprehensive validation data and documentation
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TRPV1 is a nonselective cation channel that may be activated by a wide variety of exogenous and endogenous physical and chemical stimuli. The best-known activators of TRPV1 are heat greater than 43 °C and capsaicin, the pungent compound in hot chili peppers. The activation of TRPV1 leads to painful, burning sensation. Its endogenous activators include: low pH, the endocannabinoid anandamide, N-arachidonoyl-dopamine. TRPV1 receptors are found mainly in the nociceptive neurons of the peripheral nervous system, but they have also been described in many other tissues, including the central nervous system. TRPV1 is involved in the transmission and modulation of pain, as well as the integration of diverse painful stimuli.
Type: Primary
Antigen: TRPV1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat