Specifications

Antibody Type:
Primary
Antigen Name:
Natural Cytotoxicity Triggering Receptor 1
Antigen Symbol:
NCR1
Clonality:
Polyclonal
Conjugation:
Unconjugated
Host:
Rabbit
ImmunoChemistry:
Yes
ImmunoPrecipitation:
Yes
Isotype:
IgG
Reactivity:
Rat,
Mouse
Western Blot:
Yes
Size:
200 µl
Cross Adsorption:
No
Form:
Liquid
Gene ID:
17086
Antigen Synonyms:
CD335|NCR1|NK cell-activating receptor|Lymphocyte antigen 94 homolog|Natural killer cell p46-related protein|LY94|NK-P46|NKP46
Amino Acid Number:
17 - 211
UniProtKB:
Q8C567
Storage Buffer:
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol
Molecular Weight:
26 kDa
Storage Temperature:
Store at 2...8 °C for frequent use,−20 °C for 24 months. Avoid repeated freeze-thaw cycles.
Concentration:
0.5 mg/ml (for reference only)
Shipping Temperature:
Shipped on blue ice at 4 °C
Immunogen:
recombinant NCR1 (Gln17~Thr211)
Purification:
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Cat. No.:
MSPP-PAB80MU01
Packaging:
Vial

Specifications

About this item

Polyclonal Antibody to Natural Cytotoxicity Triggering Receptor 1 (NCR1), derived from recombinant NCR1 (Gln17~Thr211), is reactive with Mouse/Rat.

High specificity, affinity and purity
Extensive validation and batch-to-batch consistency
Diverse range of conjugated and custom options
Comprehensive validation data and documentation
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Natural cytotoxicity triggering receptor 1 is a protein encoded by the NCR1 gene. By screening a human NK cell cDNA library, Pessino et al., (1998) cloned the cDNA for NKp46, or LY94, an Ig superfamily member that may cooperate with other activating receptors. The LY94 cDNA encodes a 304-amino acid type I transmembrane protein. The extracellular region is preceded by a 21-residue signal peptide with 2 cysteine-bridged C2-type Ig-like domains. A stem connects the extracellular domain to the apparently short transmembrane domain of 19 amino acids, which includes an arginine. The intracellular region contains 30 amino acids and is rich in basic residues, but does not contain any immunoreceptor tyrosine-based activating motifs (ITAM).

Caution: For research use only. Not for use in clinical diagnostic procedures. Please proper stored each component based on the instruction.

Type: Primary
Antigen: NCR1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Mouse, Rat