Specifications
- Antibody Type:Primary
- Antigen Name:Kidney Injury Molecule 1
- Antigen Symbol:Kim1
- Clonality:Polyclonal
- Conjugation:FITC (Fluorescein Isothiocyanate)
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Mouse
- Western Blot:Yes
- Size:200 µl
- Cross Adsorption:No
- Form:Liquid
- Gene ID:171283
- Antigen Synonyms:TIM1|HAVCR|T-cell immunoglobulin mucin receptor 1|HAVCR1|Hepatitis A Virus Cellular Receptor 1|TIMD1|T Cell Immunoglobulin And Mucin Domain-Containing Protein 1
- Amino Acid Number:22 - 237
- UniProtKB:Q5QNS5
- Storage Buffer:PBS, pH 7.4, containing 0.02% NaN₃, 50% glycerol
- Molecular Weight:32 kDa
- Storage Temperature:Store at 2...8 °C for frequent use,−20 °C for 24 months. Avoid repeated freeze-thaw cycles.
- Concentration:0.5 mg/ml (for reference only)
- Shipping Temperature:Shipped on blue ice at 4 °C
- Immunogen:recombinant Kim1 (Tyr22~Gly237)
- Purification:Antigen-specific affinity chromatography followed by Protein A affinity chromatography
- Cat. No.:MSPP-LA785MU81
- Packaging:Vial
Specifications
About this item
FITC-Linked Polyclonal Antibody to Kidney Injury Molecule 1 (Kim1), derived from recombinant Kim1 (Tyr22~Gly237), is reactive with Mouse.
- High specificity, affinity and purity
- Extensive validation and batch-to-batch consistency
- Diverse range of conjugated and custom options
- Comprehensive validation data and documentation
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kidney injury molecule-1 (KIM-1) is a type 1 transmembrane protein that is not detectable in normal kidney tissue but is expressed at high levels in rodent kidneys with dedifferentiated proximal tubule epithelial cells after ischemic or toxic injury. Sequence analysis predicted that the 359-amino acid type I HAVCR1 glycoprotein, which is 79% identical to the monkey protein, contains a signal sequence; a 109-amino acid cys-rich N-terminal region with only 1 conserved N-glycosylation site; a 163-amino acid TSP-rich region with 3 N-glycosylation sites, 2 of which are conserved; and a 48-amino acid intracellular domain, 12 residues shorter than that of the monkey protein. Northern blot analysis revealed ubiquitous expression of a 4.4-kb HAVCR1 transcript, with highest levels in kidney and testis.
Type: Primary
Antigen: Kim1
Clonality: Polyclonal
Clone:
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Mouse