Anti-SIGLEC10 Mouse Monoclonal Antibody [clone: C5]

MSPP-MD921HU21

: CLOUD-CLONE CORP MS

Anti-SIGLEC10 Mouse Monoclonal Antibody [clone: C5]

MSPP-MD921HU21

: CLOUD-CLONE CORP MS

: MAD921HU21

Antibody Type:
Primary
Antigen Name:
Sialic Acid Binding Ig Like Lectin 10
Antigen Symbol:
SIGLEC10
Clonality:
Monoclonal
Clone:
C5
Conjugation:
Unconjugated
Host:
Mouse
ImmunoChemistry:
Yes
Isotype:
IgG1 kappa
Reactivity:
Human
Western Blot:
Yes
Size:
200 µl
Cross Adsorption:
No
Form:
Liquid
Gene ID:
89790
Antigen Synonyms:
Siglec-Like Gene 2|PRO940|SLG2|Sialic Acid Binding Ig-Like Lectin 10 Ig-Like Lectin 7
Amino Acid Number:
571 - 697
UniProtKB:
Q96LC7
Storage Buffer:
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol
Molecular Weight:
17 kDa
Storage Temperature:
Store at 2...8 °C for frequent use, −20 °C for 24 months. Avoid repeated freeze-thaw cycles.
Concentration:
1 mg/ml (for reference only)
Shipping Temperature:
Shipped on blue ice at 4 °C
Immunogen:
Recombinant SIGLEC10 (Met571~Gln697)
Purification:
Protein A + Protein G affinity chromatography
Cat. No.:
MSPP-MD921HU21
Packaging:
Vial

Monoclonal Antibody to Sialic Acid Binding Ig Like Lectin 10 (SIGLEC10), derived from recombinant SIGLEC10 (Met571~Gln697), is reactive with Human.

High specificity, affinity, and purity
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By searching an EST database for sequences resembling CD33 (SIGLEC3) and screening a spleen cDNA library, Munday et al. (2001) isolated a cDNA encoding SIGLEC10. Sequence analysis predicted that the 697-amino acid SIGLEC10 protein contains a signal peptide, an N-terminal V-set Ig-like domain and 4 C2-set Ig-like domains, 5 potential N-linked glycosylation sites, a transmembrane region, and a 126-residue cytoplasmic tail with 3 putative ITIMs. Northern blot analysis detected a major 3.0-kb SIGLEC10 transcript, with highest levels in spleen, lymph node, blood leukocytes, and appendix. Little or no expression was observed in pancreas, thyroid, and testis. Flow cytometric analysis demonstrated eosinophil-specific expression of SIGLEC10, but at a lower level than that of SIGLEC8.

: For research use only. Not for use in clinical diagnostic procedures. Please proper stored each component based on the instruction.

Type: Primary
Antigen: SIGLEC10
Clonality: Monoclonal
Clone: C5
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human