Specifications
- Antibody Type:Primary
- Antigen Name:Lymphocyte Activation Gene 3
- Antigen Symbol:LAG3
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoPrecipitation:Yes
- Isotype:IgG
- Reactivity:Mouse
- Western Blot:Yes
- Size:200 µl
- Cross Adsorption:No
- Form:Liquid
- Gene ID:16768
- Antigen Synonyms:CD223|Protein FDC
- Amino Acid Number:274 - 504
- UniProtKB:Q61790
- Storage Buffer:0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol
- Molecular Weight:28 kDa
- Storage Temperature:Store at 2...8 °C for frequent use, −20 °C for 24 months. Avoid repeated freeze-thaw cycles.
- Concentration:1 mg/ml (for reference only)
- Shipping Temperature:Shipped on blue ice at 4 °C
- Immunogen:Recombinant LAG3 (Leu274~Gln504)
- Purification:Antigen-specific affinity chromatography followed by Protein A affinity chromatography
- Cat. No.:MSPP-PAB663MU1
- Packaging:Vial
Specifications
About this item
Polyclonal Antibody to Lymphocyte Activation Gene 3 (LAG3), derived from recombinant LAG3 (Leu274~Gln504), is reactive with Mouse.
- High specificity, affinity, and purity
- Extensive validation and batch-to-batch consistency
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Lymphocyte-activation protein 3 belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4.Triebel et al. (1990) identified a novel human gene of the Ig superfamily, which they designated LAG3. Expression of this gene was undetectable in resting peripheral blood lymphocytes, whereas it was found in activated T and NK cells. The corresponding cDNA encodes a 498-amino acid membrane protein with 4 extracellular Ig-like domains. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. The 2 genes are probably derived from a common evolutionary ancestor.
Type: Primary
Antigen: LAG3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Mouse