Specifications
- Antibody Type:Primary
- Antigen Name:Sodium Hydrogen Exchange Regulatory Cofactor 2
- Antigen Symbol:SLC9A3R2
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoPrecipitation:Yes
- Isotype:IgG
- Reactivity:Pig,Human
- Western Blot:Yes
- Size:200 µl
- Cross Adsorption:No
- Form:Liquid
- Gene ID:9351
- Antigen Synonyms:TKA1|OCTS2|NHERF2|Tyrosine Kinase Activator Protein 1|SIP1|E3KARP|Solute Carrier Family 9 Member 3 Regulator 2|SRY-interacting protein 1
- Amino Acid Number:56 - 337
- UniProtKB:Q15599
- Storage Buffer:PBS, pH 7.4, containing 0.02% NaN₃, 50% glycerol
- Molecular Weight:44 kDa
- Storage Temperature:Store at 2...8 °C for frequent use, −20 °C for 24 months. Avoid repeated freeze-thaw cycles.
- Concentration:0.5 mg/ml (for reference only)
- Shipping Temperature:Shipped on blue ice at 4 °C
- Immunogen:Recombinant SLC9A3R2 (Leu56~Phe337)
- Purification:Antigen-specific affinity chromatography followed by Protein A affinity chromatography
- Cat. No.:MSPP-PAB976HU1
- Packaging:Vial
Specifications
About this item
Polyclonal Antibody to Sodium Hydrogen Exchange Regulatory Cofactor 2 (SLC9A3R2), derived from recombinant SLC9A3R2 (Leu56~Phe337), is reactive with Human/Pig.
- High specificity, affinity, and purity
- Extensive validation and batch-to-batch consistency
- Diverse range of conjugated and custom options
- Comprehensive validation data and documentation
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Tyrosine kinase activator protein 1 is a human scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. It is necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May also act as scaffold protein in the nucleus. This regulatory protein (factor) interacts with a sodium/hydrogen exchanger NHE3 (SLC9A3) in the brush border membrane of the proximal tubule, small intestine, and colon that plays a major role in transepithelial sodium absorption. SLC9A3R2, as well as SLC9A3R1 and protein kinase A phosphorylation, may play a role in NHE3 regulation.
Type: Primary
Antigen: SLC9A3R2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human;Pig