Specifications

Antibody Type:
Primary
Antigen Name:
Interferon Alpha/Beta Receptor 2
Antigen Symbol:
IFNa/bR2
Clonality:
Polyclonal
Conjugation:
Unconjugated
Host:
Rabbit
ImmunoChemistry:
Yes
ImmunoFluorescence:
Yes
Isotype:
IgG
Reactivity:
Pig,
Human,
Rat,
Mouse
Western Blot:
Yes
Size:
200 µl
Cross Adsorption:
No
Form:
Liquid
Gene ID:
3455
Antigen Synonyms:
IFNARB|Type I interferon receptor 2|IFN-R|IFN-alpha-REC|IFNABR|IFNAR2|Interferon(Alpha,Beta And Omega)Receptor Beta Chain|Interferon alpha binding protein
Amino Acid Number:
27 - 243
UniProtKB:
P48551
Storage Buffer:
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol
Molecular Weight:
29 kDa
Storage Temperature:
Store at 2...8 °C for frequent use, –20 ℃ for 24 months. Avoid repeated freeze-thaw cycles.
Concentration:
0.5 mg/ml (for reference only)
Shipping Temperature:
Shipped on blue ice at 4 °C.
Immunogen:
Recombinant IFNa/bR2 (Ile27~Lys243)
Purification:
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Cat. No.:
MSPP-PAE171HU1
Packaging:
Vial

Specifications

About this item

Polyclonal Antibody to Interferon Alpha/Beta Receptor 2 (IFNa/bR2), derived from recombinant IFNa/bR2 (Ile27~Lys243), is reactive with Human/Mouse/Rat/Pig.

High specificity, affinity, and purity
Extensive validation and batch-to-batch consistency
Diverse range of conjugated and custom options
Comprehensive validation data and documentation
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IFNAR2 was identified by several groups, including Novick et al. (1994), Lutfalla et al. (1995), and Domanski et al. (1995). Lutfalla et al. (1995) reported the structure of the IFNAR2 gene and showed that it is located at chromosome 21q22.1 in a cluster with the class II cytokine receptor genes CRFB4 (IL10RB), IFNAR1, and AF1. They found evidence for alternative splicing of the IFNAR2 gene and showed that one of the transcripts, ifnar2-2, could functionally complement the IFN-alpha/beta receptor-defective mutant U5A cell line. Raz et al. (1995) independently reported using human-hamster somatic cell hybrids to map IFNAR2 to 21q22.1. There was no significant difference in RNA expression of the F8 and S8 IFNAR2 variants, but FACS analysis demonstrated higher cell surface expression of the F8 variant.

Caution: For research use only. Not for use in clinical diagnostic procedures. Please properly store each component based on the instruction.

Type: Primary
Antigen: IFNa/bR2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat, Pig